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Osteogenesis Imperfecta: Disease Bioinformatics

Research of Osteogenesis Imperfecta has been linked to Fracture, Osteoporosis, Bone Diseases, Osteogenesis Imperfecta Type I, Congenital Abnormality. The study of Osteogenesis Imperfecta has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Osteogenesis Imperfecta include Dentinogenesis, Secretion, Pathogenesis, Bone Resorption, Ossification. These pathways complement our catalog of research reagents for the study of Osteogenesis Imperfecta including antibodies and ELISA kits against COL1A2, COL1A1, DMD, BEST1, LEPRE1.

Osteogenesis Imperfecta Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Osteogenesis Imperfecta below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1031 products for the study of Osteogenesis Imperfecta that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-92790
Western Blot: COL1A2 Antibody [NBP2-92790] - Analysis of extracts of various cell lines, using COL1A2 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.Immunohistochemistry-Paraffin: COL1A2 Antibody [NBP2-92790] - Paraffin-embedded rat brain using COL1A2.

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, ICC/IF, IHC

NB600-408
Immunohistochemistry-Paraffin: Collagen I Antibody [NB600-408] - Rat colon tissue stained with Collagen I antibody (red) and Hoechst (blue). IHC-P image submitted by a verified customer review.Immunocytochemistry/Immunofluorescence: Collagen I Antibody [NB600-408] - Myofibroblast differentiation requires CD271/NGF activation. Representative alphaSMA (red) and COLLAGEN 1 (red) immunostaining with DAPI (blue) in non-treated (control), TGFbeta-treated cells with or without gamma-secretase inhibitor. Scale bars: 50 um Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-019-09992-3) licensed under a CC-BY licence.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, FLISA

     14 Reviews

186 Publications
NBP1-89953
Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining in human skeletal muscle and tonsil tissues. Corresponding DMD RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

3 Publications
NB300-164
Dual RNAscope ISH-IHC: Bestrophin 1 Antibody (E6-6) [NB300-164] - Formalin-fixed paraffin-embedded tissue sections of human duodenum were probed for Bestrophin 1 mRNA (ACD RNAScope Probe, catalog # 433181; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse anti-human  (Novus Biologicals catalog # NB300-164) at 0.3ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue).  IHC signal is confined to cytoplasm.Immunohistochemistry-Paraffin: Bestrophin 1 Antibody (E6-6) [NB300-164] - Bestrophin 1 was detected in immersion fixed paraffin sections of human small intestine using t Mouse Anti-Human Bestrophin 1 Monoclonal Antibody (Catalog # NB300-164) at 5 ug/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cell surface and extracellular.

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, ICC/IF, IHC

     1 Review

40 Publications
H00064175-M01
Western Blot: LEPRE1 Antibody (3C7) [H00064175-M01] - LEPRE1 monoclonal antibody (M01), clone 3C7 Analysis of LEPRE1 expression in HeLa.Immunocytochemistry/Immunofluorescence: LEPRE1 Antibody (3C7) [H00064175-M01] - Analysis of monoclonal antibody to LEPRE1 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

5 Publications
H00010491-M01
Western Blot: CRTAP Antibody (4D9) [H00010491-M01] - CRTAP monoclonal antibody (M01), clone 4D9 Analysis of CRTAP expression in HeLa.Immunohistochemistry-Paraffin: CRTAP Antibody (4D9) [H00010491-M01] - Analysis of monoclonal antibody to CRTAP on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

3 Publications
NB120-14817

Mouse Monoclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

     1 Review

6 Publications
MAB1419
Saos‑2 human osteosarcoma cell line was stained with Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=Human osteoblasts were stained with Mouse Anti-Human/Rat Osteocalcin Monoclonal Antibody (Catalog # MAB1419, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=

Mouse Monoclonal
Species Human, Rat
Applications IHC, CyTOF-ready, ICC

     2 Reviews

23 Publications
NBP2-60629
ELISA: Human PTH ELISA Kit (Colorimetric) [NBP2-60629]


Species Human

1 Publication
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP2-56244
Western Blot: Musculin Antibody [NBP2-56244] - Western blot analysis in human cell line RT-4.Immunocytochemistry/Immunofluorescence: Musculin Antibody [NBP2-56244] - Staining of human cell line SK-MEL-30 shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP2-49242
Western Blot: FKBP10 Antibody [NBP2-49242] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251 MGImmunohistochemistry-Paraffin: FKBP10 Antibody [NBP2-49242] - Staining of human placenta shows moderate to strong cytoplasmic positivity in fibroblasts.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-85358
Immunohistochemistry-Paraffin: Cyclophilin B Antibody [NBP1-85358] - Staining in human thyroid gland and skeletal muscle tissues using anti-PPIB antibody. Corresponding PPIB RNA-seq data are presented for the same tissues.Western Blot: Cyclophilin B Antibody [NBP1-85358] - Analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     1 Review

2 Publications
NBP1-97491
Western Blot: Hsp47 Antibody (M16.10A1) [NBP1-97491] - analysis of Hsp47 in NIH/3T3 cell lysate (20ug/lane) using anti-Hsp47 antibody. 5x10^4 NIH/3T3 cells were seeded in 6-well plate and transfected with 50nM of HSP47 siRNA the following day. Total protein was harvested 72h after transfection. Image from verified customer review.Immunocytochemistry/Immunofluorescence: Hsp47 Antibody (M16.10A1) [NBP1-97491] - WNT and BMP signaling pathways play crucial roles in regeneration. a-d Real-time PCR for WNT and BMP signals, including Wnt7b Dual immunostaining for K15 and phospho-Smad1/5 (pSmad1/5) revealed the nuclear staining of pSmad1/5 in hair stem cells at day 7 when skin was stretched (arrow). Scale bar?=?50?um. h, i Immunostaining and confocal microscope. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41467-019-09402-8) licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     2 Reviews

12 Publications
AF1177
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, human liver tissue, and human breast tissue. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Human/Mouse Serpin F1/PEDF Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1177) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Western  blot shows lysates of P19 mouse embryonal carcinoma cell line. PVDF membrane  was probed with 2 µg/mL of Goat Anti-Human/Mouse Serpin F1/PEDF  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1177) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, IHC

8 Publications

Related PTMs

Osteogenesis Imperfecta has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Osteogenesis Imperfecta is also known as osteogenesis imperfecta, brittle bone disease, osteopsathyrosis, osteogenesis imperfecta, recessive perinatal lethal, ekman-lobstein disease, lobstein's syndrome, lobstein's disease, vrolik's disease.