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Nicotine Dependence: Disease Bioinformatics

Research of Nicotine Dependence has been linked to Tobacco Use Disorder, Depressive Disorder, Substance-related Disorders, Substance Withdrawal Syndrome, Mental Disorders. The study of Nicotine Dependence has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Nicotine Dependence include Response To Nicotine, Sensitization, Cognition, Pathogenesis, Translation. These pathways complement our catalog of research reagents for the study of Nicotine Dependence including antibodies and ELISA kits against CHRNA4, NICOTINIC ACETYLCHOLINE RECEPTOR, CHRNA5, CYP2A6, NDP.

Nicotine Dependence Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nicotine Dependence below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1003 products for the study of Nicotine Dependence that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-61674
Western Blot: Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (7B4H1) [NBP2-61674] - Analysis using CHRNA4 mAb against HEK293 (1) and CHRNA4 (AA: 29-242)-hIgGFc transfected HEK293 (2) cell lysate.Flow Cytometry: Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (7B4H1) [NBP2-61674] - Analysis using CHRNA4 mouse mAb against SH-SY5Y (1) cell lysate.

Mouse Monoclonal
Species Human
Applications WB, ELISA

NBP2-61677
Western Blot: Nicotinic Acetylcholine R alpha 5/CHRNA5 Antibody (2D2D10) [NBP2-61677] - Analysis using CHRNA5 mAb against HEK293 (1) and CHRNA5 (AA: 23-254)-hIgGFc transfected HEK293 (2) cell lysate.Flow Cytometry: Nicotinic Acetylcholine R alpha 5/CHRNA5 Antibody (2D2D10) [NBP2-61677] - Analysis of SK-N-SH cells using CHRNA5 mouse mAb (green) and negative control (red).

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, Flow

NBP2-01437
Western Blot: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Analysis of extracts (35ug) from 9 different cell lines by using anti-Cytochrome P450 2A6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunohistochemistry-Paraffin: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Staining of paraffin-embedded Human prostate tissue using anti-Cytochrome P450 2A6 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

AF3014

Goat Polyclonal
Species Human
Applications WB, IHC, Block

4 Publications
NLS1403
Immunohistochemistry-Paraffin: Dopamine D2 R/DRD2 Antibody [NLS1403] - Analysis of anti-DRD2 antibody with human brain, neurons and glia at 3 ug/ml.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

2 Publications
NBP2-94035
Western Blot: TEF1 Antibody [NBP2-94035] -  Analysis of extracts of various cell lines, using TEAD1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit. Exposure time: 1s.Immunocytochemistry/Immunofluorescence: TEF1 Antibody [NBP2-94035] - Analysis of MCF7 cells using TEF1.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF

NBP2-61673
Western Blot: Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody (6D3A10) [NBP2-61673] - Analysis using CHRNA3 mAb against human CHRNA3 (AA: 32-240) recombinant protein. (Expected MW is 50.6 kDa)Immunocytochemistry/Immunofluorescence: Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody (6D3A10) [NBP2-61673] - Analysis of SMMC-7721 cells using CHRNA3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

H00009455-D01P
Western Blot: HOMER2 Antibody [H00009455-D01P] - Analysis of HOMER2 expression in mouse brain.Immunocytochemistry/Immunofluorescence: HOMER2 Antibody [H00009455-D01P] - Analysis of antibody to HOMER2 on HeLa cell. Antibody concentration 30 ug/ml.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF

1 Publication
NBP2-61743
Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody (1H11F2) [NBP2-61743] - Analysis using CHRNB4 mAb against human CHRNB4 (AA: extra 22-236) recombinant protein. (Expected MW is 51 kDa)Immunocytochemistry/Immunofluorescence: Nicotinic Acetylcholine Receptor beta 4 Antibody (1H11F2) [NBP2-61743] - Analysis of Hela cells using CHRNB4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NB100-41387
Western Blot: COMT Antibody [NB100-41387] - Staining of Human Testis lysate (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: COMT Antibody [NB100-41387] - Staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Antibody at 3.75 ug/mL.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NB100-1892
Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NB100-1892] - Human Colon lysate, 35 ug protein in RIPA buffer. Antibody at 2 ug/mL. Detection by chemiluminescence.Immunocytochemistry/Immunofluorescence: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NB100-1892] - Analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Goat Polyclonal
Species Human
Applications WB, ICC/IF, PEP-ELISA

1 Publication
248-BDB
2 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE underreducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Bluestaining, showing bands at 13-14 kDa and 11-12 kDa, respectively.    Recombinant Human  BDNF (Catalog #    248-BDB) stimulates cell proliferation in  the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2‑2 ng/mL.


Species Human, Mouse, Rat

     1 Review

163 Publications
NBP1-92172
Western Blot: NDUFB6 Antibody [NBP1-92172] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissueImmunocytochemistry/Immunofluorescence: NDUFB6 Antibody [NBP1-92172] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
AF4928
K562 human chronic myelogenous leukemia cell line was stained with Goat Anti-Human ERMAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4928, filled histogram) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

NBP1-00178
Immunocytochemistry/Immunofluorescence: DIO2 Antibody [NBP1-00178] - Analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton.Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear and  cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).Immunohistochemistry-Frozen: DIO2 Antibody [NBP1-00178] - IHC analysis of DIO2 in cryo-sectioned Mouse Hippocampus using NBP1-00178 at 2ug/ml. Microwaved antigen retrieval with citrate buffer pH 4.5, HRP-staining.

Goat Polyclonal
Species Human, Mouse, Sheep
Applications WB, Flow, ICC/IF

6 Publications
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Staining of NIH3T3 cell lysate with antibody at 0.3 ug/mL (A) and Rat Brain cell lysate with antibody at 2 ug/mL (B). 35 ug protein in RIPA buffer. Detected by chemiluminescence.Immunohistochemistry: POMC Antibody [NB100-1533] - Representative confocal images of POMC in POMC-transfected WT and Sel1L-/- N2a cells. White arrows point to POMC-containing secretory granules, while yellow arrows point to perinuclear POMC. KDEL marks the ER. Representative data from at least 2 independent experiments are shown. Image collected and cropped by CiteAb from the following publication (jci.org/articles/view/96420), licensed under a CC-BY licence.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

10 Publications
NBP2-22164
Western Blot: SLC6A3/DAT1 Antibody (mAb16) [NBP2-22164] - Western blot analysis of DAT protein. Band shown at approx. 75 kDa. Image submitted by verified customer review. Immunocytochemistry/Immunofluorescence: DAT1 Antibody (mAb16) [NBP2-22164] - The DAT1 antibody was tested in PC12 cells at a 1:250 dilution against DyLight 488 (Green). Actin and nuclei were counterstained with Phalloidin-AlexaFluor 568 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Mouse, Rat, Human (Negative)
Applications WB, ELISA, ICC/IF

     3 Reviews

12 Publications
NB300-560
Western Blot: ER alpha/NR3A1 Antibody (33) [NB300-560] - Analysis of recombinant ER alpha.Immunohistochemistry-Paraffin: ER alpha/NR3A1 Antibody (33) [NB300-560] - Human breast tissue (B) and magnified section (C) compared with an isotype control (A).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-Fr

     1 Review

7 Publications
NBP2-92717
Western Blot: Dopamine Receptor D4 Antibody [NBP2-92717] - Analysis of extracts of various cell lines, using Dopamine Receptor D4 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NBP2-92717] - Paraffin-embedded rat retina using Dopamine Receptor D4.

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, IHC, IHC-P