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Nicotine Dependence: Disease Bioinformatics

Research of Nicotine Dependence has been linked to Tobacco Use Disorder, Depressive Disorder, Substance-related Disorders, Substance Withdrawal Syndrome, Mental Disorders. The study of Nicotine Dependence has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Nicotine Dependence include Response To Nicotine, Sensitization, Cognition, Pathogenesis, Translation. These pathways complement our catalog of research reagents for the study of Nicotine Dependence including antibodies and ELISA kits against CHRNA4, NICOTINIC ACETYLCHOLINE RECEPTOR, CHRNA5, CYP2A6, NDP.

Nicotine Dependence Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Nicotine Dependence below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1050 products for the study of Nicotine Dependence that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NLS3921
Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Anti-DRD4 / Dopamine Receptor D4 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.Immunohistochemistry-Paraffin: Dopamine Receptor D4 Antibody [NLS3921] - Staining of human brain, Neurons and Glia

Rabbit Polyclonal
Species Human, Monkey, Primate
Applications IHC, IHC-P

NBP1-00178
Immunocytochemistry/Immunofluorescence: DIO2 Antibody [NBP1-00178] - Analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton.Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear and  cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).Immunohistochemistry-Frozen: DIO2 Antibody [NBP1-00178] - IHC analysis of DIO2 in cryo-sectioned Mouse Hippocampus using NBP1-00178 at 2ug/ml. Microwaved antigen retrieval with citrate buffer pH 4.5, HRP-staining.

Goat Polyclonal
Species Human, Mouse, Sheep
Applications WB, Flow, ICC/IF

7 Publications
H00009455-D01P
Western Blot: HOMER2 Antibody [H00009455-D01P] - Analysis of HOMER2 expression in mouse brain.Immunocytochemistry/Immunofluorescence: HOMER2 Antibody [H00009455-D01P] - Analysis of antibody to HOMER2 on HeLa cell. Antibody concentration 30 ug/ml.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF

1 Publication
NB300-560
Western Blot: ER alpha/NR3A1 Antibody (33) [NB300-560] - Analysis of recombinant ER alpha.Immunohistochemistry-Paraffin: ER alpha/NR3A1 Antibody (33) [NB300-560] - Human breast tissue (B) and magnified section (C) compared with an isotype control (A).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-Fr

     1 Review

8 Publications
NBP1-92172
Western Blot: NDUFB6 Antibody [NBP1-92172] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissueImmunocytochemistry/Immunofluorescence: NDUFB6 Antibody [NBP1-92172] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
NB100-1780
Western Blot: COMT Antibody [NB100-1780] - Staining of MCF7 (A) with antibody at 0.5 ug/mL, U251 cell lysate 1 (B) and U251 cell lysate 2 (C) (35 ug protein in RIPA buffer) with antibody at 1 ug/mL. Detected by chemiluminescence.Flow Cytometry: COMT Antibody [NB100-1780] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human, Mouse
Applications WB, Flow, PEP-ELISA

3 Publications
NBP2-01437
Western Blot: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Analysis of extracts (35ug) from 9 different cell lines by using anti-Cytochrome P450 2A6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunohistochemistry-Paraffin: Cytochrome P450 2A6 Antibody (OTI1D2) [NBP2-01437] - Staining of paraffin-embedded Human prostate tissue using anti-Cytochrome P450 2A6 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

NBP2-22164
Western Blot: SLC6A3/DAT1 Antibody (mAb16) [NBP2-22164] - Western blot analysis of DAT protein. Band shown at approx. 75 kDa. Image submitted by verified customer review. Immunocytochemistry/Immunofluorescence: DAT1 Antibody (mAb16) [NBP2-22164] - The DAT1 antibody was tested in PC12 cells at a 1:250 dilution against DyLight 488 (Green). Actin and nuclei were counterstained with Phalloidin-AlexaFluor 568 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Mouse, Rat, Human (Negative)
Applications WB, ELISA, ICC/IF

     3 Reviews

13 Publications
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Staining of NIH3T3 cell lysate with antibody at 0.3 ug/mL (A) and Rat Brain cell lysate with antibody at 2 ug/mL (B). 35 ug protein in RIPA buffer. Detected by chemiluminescence.Immunohistochemistry: POMC Antibody [NB100-1533] - Representative confocal images of POMC in POMC-transfected WT and Sel1L-/- N2a cells. White arrows point to POMC-containing secretory granules, while yellow arrows point to perinuclear POMC. KDEL marks the ER. Representative data from at least 2 independent experiments are shown. Image collected and cropped by CiteAb from the following publication (jci.org/articles/view/96420), licensed under a CC-BY licence.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

10 Publications
AF3014

Goat Polyclonal
Species Human
Applications WB, IHC, Block

4 Publications
AF4928
K562 human chronic myelogenous leukemia cell line was stained with Goat Anti-Human ERMAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4928, filled histogram) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Flow, CyTOF-ready

MAB9266
    Dopamine  D2 R/DRD2 was detected in immersion fixed paraffin-embedded sections of human  brain (striatum) using Mouse Anti-Human Dopamine D2 R/DRD2 Monoclonal  Antibody (Catalog # MAB9266) at 5 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Mouse IgG  VisUCyte™  HRP Polymer  Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications IHC

H00006532-D01P
Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [H00006532-D01P] - Analysis of SLC6A4 expression in mouse lung.Flow Cytometry: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [H00006532-D01P] - Fixed and permeabilized mouse mast cells were stained for 1 hour in 4C then stained with PE secondary and ran on FACS. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse
Applications WB

     1 Review

1 Publication
NBP2-61673
Western Blot: Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody (6D3A10) [NBP2-61673] - Analysis using CHRNA3 mAb against human CHRNA3 (AA: 32-240) recombinant protein. (Expected MW is 50.6 kDa)Immunocytochemistry/Immunofluorescence: Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody (6D3A10) [NBP2-61673] - Analysis of SMMC-7721 cells using CHRNA3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

1 Publication
NBP2-61674
Western Blot: Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (7B4H1) [NBP2-61674] - Analysis using CHRNA4 mAb against HEK293 (1) and CHRNA4 (AA: 29-242)-hIgGFc transfected HEK293 (2) cell lysate.Flow Cytometry: Nicotinic Acetylcholine R alpha 4/CHRNA4 Antibody (7B4H1) [NBP2-61674] - Analysis using CHRNA4 mouse mAb against SH-SY5Y (1) cell lysate.

Mouse Monoclonal
Species Human
Applications WB, ELISA

NBP2-61677
Western Blot: Nicotinic Acetylcholine R alpha 5/CHRNA5 Antibody (2D2D10) [NBP2-61677] - Analysis using CHRNA5 mAb against HEK293 (1) and CHRNA5 (AA: 23-254)-hIgGFc transfected HEK293 (2) cell lysate.Flow Cytometry: Nicotinic Acetylcholine R alpha 5/CHRNA5 Antibody (2D2D10) [NBP2-61677] - Analysis of SK-N-SH cells using CHRNA5 mouse mAb (green) and negative control (red).

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, Flow

NBP2-61743
Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody (1H11F2) [NBP2-61743] - Analysis using CHRNB4 mAb against human CHRNB4 (AA: extra 22-236) recombinant protein. (Expected MW is 51 kDa)Immunocytochemistry/Immunofluorescence: Nicotinic Acetylcholine Receptor beta 4 Antibody (1H11F2) [NBP2-61743] - Analysis of Hela cells using CHRNB4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

248-BDB
2 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE underreducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Bluestaining, showing bands at 13-14 kDa and 11-12 kDa, respectively.    Recombinant Human  BDNF (Catalog #    248-BDB) stimulates cell proliferation in  the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2‑2 ng/mL.


Species Human, Mouse, Rat
Applications Bind, BA

     1 Review

192 Publications
NBP2-94035
Western Blot: TEF1 Antibody [NBP2-94035] -  Analysis of extracts of various cell lines, using TEAD1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit. Exposure time: 1s.Immunocytochemistry/Immunofluorescence: TEF1 Antibody [NBP2-94035] - Analysis of MCF7 cells using TEF1 .

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF