Narcolepsy is a neurological disorder affecting the part of the brain that regulates sleep. Those suffering from narcolepsy can experience excessive daytime sleepiness, hallucinations, and sudden loss of muscle control. A normal sleep cycle is about 100 to 110 minutes, beginning with NREM (non rapid eye movement) sleep and transitioning to REM(rapid eye movement) sleep after 80 to 100 minutes. People with narcolepsy frequently enter REM sleep within a few minutes of falling asleep. Narcolepsy effects both men and women equally and is widespread throughout the world. It mostly begins during a person’s childhood and is lifelong. Diagnosis of the condition can take a long time in most cases more than a year and sometimes as long as several decades because narcolepsy symptoms are often mistakenly linked to other sleep disorders or medical conditions such as depression. The only unique symptom of narcolepsy is cataplexy this happens when you lose the ability to control your muscles. Narcolepsy with cataplexy is estimated to affect about one in every 2,000 people in the USA. When cataplexy is present, narcolepsy is almost always caused by the lack of a brain neurotransmitters called hypocretin. Neurotransmitters are chemicals that neurons produce to communicate with each other. Loss of hypocretin results in an inability to regulate sleep. In cases without cataplexy, the disorder may be caused by a lack of hypocretin or by various other causes. People with narcolepsy can fight off the urge to fall asleep with exercise this will keep your heart rate elevated and more awake during the day.
Narcolepsy Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Narcolepsy below!
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We have 1181 products for the study of Narcolepsy that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.