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Myopathies, Nemaline: Disease Bioinformatics

Research of Myopathies, Nemaline has been linked to Myopathy, Weakness, Muscle Weakness, Congenital Myopathy (disorder), Central Core Myopathy (disorder). The study of Myopathies, Nemaline has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Myopathies, Nemaline include Pathogenesis, Muscle Contraction, Muscle Atrophy, Localization, Regeneration. These pathways complement our catalog of research reagents for the study of Myopathies, Nemaline including antibodies and ELISA kits against NEB, ACTA1, TPM3, RYR1, TPM1.

Myopathies, Nemaline Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Myopathies, Nemaline below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1183 products for the study of Myopathies, Nemaline that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

NBP1-87752
Immunohistochemistry-Paraffin: Nebulin Antibody [NBP1-87752] - Staining of human tonsil shows no positivity in lymphoid cells as expected.Immunohistochemistry-Paraffin: Nebulin Antibody [NBP1-87752] - Staining of human colon shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NB100-74340
Western Blot: Actin Antibody (mAbGEa) [NB100-74340] - Total protein from HeLa, 3T3, PC12 and Bovine normal tissue was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 1.0 ug/mL anti-Actin in 5% blocking buffer and detected with an anti-mouse IgM secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: Actin Antibody (mAbGEa) [NB100-74340] - NIH-3T3 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.05% Triton X-100. The cells were incubated with anti-Actin (mAbGEa) at 5 ug/mL overnight at 4C and detected with an anti-Mouse IgM DyLight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

     8 Reviews

29 Publications
H00007170-M02
Western Blot: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Enrichment of tumor proteins in plasma-derived EVs and classifier performance. Immunoblot analysis of plasma-derived extracellular vesicles from adenocarcinoma cases and matched controls to demonstrate marker performance in immunoassay. Marker abundance as quantified by densitometry of western blot, lower left; ROC curve analysis of TPM3 performance based on western blot data, lower right. Image collected and cropped by CiteAb from the following publication (//www.oncotarget.com/fulltext/20748) licensed under a CC-BY licence.Immunohistochemistry-Paraffin: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Analysis of monoclonal antibody to TPM3 on formalin-fixed paraffin-embedded human smooth muscle. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

2 Publications
NB300-543
Immunohistochemistry-Paraffin: Ryanodine Receptor Antibody (34C) [NB300-543] - Biopsies of deparaffinized Human skeletal muscle tissue.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

12 Publications
NB100-1908
Immunocytochemistry/Immunofluorescence: Tropomyosin-1 Antibody (TM311) [NB100-1908] - Localization of microfilament associated proteins in PTK2 cells using (1) Monoclonal Anti-Tropomyosin, (2) Monoclonal Anti-Myosin (Light Chain),  and (3) Monoclonal Anti-alpha-ActininImmunocytochemistry/Immunofluorescence: Tropomyosin-1 Antibody (TM311) [NB100-1908] - A formaldehyde-fixed cardiomyocyte isolated from rat heart using Monoclonal Anti-Tropomyosin (36/39 kDa) produced in mouse

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

3 Publications
MAB4470
    Myosin  Heavy Chain was detected in immersion fixed paraffin-embedded sections of  human skeletal muscle using Mouse Anti-Myosin Heavy Chain Monoclonal Antibody  (Catalog # MAB4470) at 5 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Mouse IgG  VisUCyte™ HRP Polymer Antibody (Catalog # <a class=    Myosin  Heavy Chain was detected in perfusion fixed frozen sections of mouse skeletal  muscle using Mouse Anti-Myosin Heavy Chain Monoclonal Antibody (Catalog #  MAB4470) at 5 µg/mL for 1 hour at room temperature  followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP  Polymer Antibody (Catalog # <a class=

Mouse Monoclonal
Species Multi-Species
Applications WB, IHC, ICC

     6 Reviews

50 Publications
AF3844
Desmin was detected in immersion fixed frozen sections of mouse skeletal muscle using Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=Desmin was detected in immersion fixed paraffin-embedded sections of human heart using 15 µg/mL Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <A class=

Goat Polyclonal
Species Human, Mouse
Applications IHC

     2 Reviews

13 Publications
H00007138-B01P
Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P] - Human skeletal muscle lysate. Image from verified customer review.Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P] - Analysis of TNNT1 expression in transfected 293T cell line by TNNT1 polyclonal antibody.  Lane 1: TNNT1 transfected lysate(27.61 KDa). Lane 2: Non-transfected lysate.

Mouse Polyclonal
Species Human, Invertebrate
Applications WB

     1 Review

2 Publications
NBP2-95197
Western Blot: tropomyosin-2 Antibody [NBP2-95197] - Analysis of extracts of various cell lines, using tropomyosin-2 at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.Immunocytochemistry/Immunofluorescence: tropomyosin-2 Antibody [NBP2-95197] - Paraffin-embedded human breast cancer using tropomyosin-2.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-38361
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human testis.Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skeletal muscle shows high expression.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-88071
Immunocytochemistry/Immunofluorescence: Titin Antibody [NBP1-88071] - SMYD2 Cys13 glutathionylation or oxidation reduces myofibril integrity. Monitoring the myofibril alignment in rat neonatal cardiomyocytes upon incubation of AMA (2 ug/mL) for 12 h: no expression of SMYD2 WT. Immunostainings were done by using antibodies to SMYD2, HA (green), or titin (alpha-titin-NT, red). About 30 cells were photographed and examined for myofibril alignment or directionality by FiberFit software. 34 Images represent the major myofibril structure in individual conditions. Scale bars, 10 um. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41467-018-06786-x), licensed under a CC-BY licence.Immunohistochemistry-Paraffin: Titin Antibody [NBP1-88071] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-P

3 Publications
NBP2-38544
Western Blot: Cofilin 2 Antibody [NBP2-38544] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG.  Lane 4: Human Plasma.  Lane 5: Human liver tissueImmunocytochemistry/Immunofluorescence: Cofilin 2 Antibody [NBP2-38544] - Staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-86113
Immunocytochemistry/Immunofluorescence: Myotubularin Antibody [NBP1-86113] - Staining of human cell line U-251 MG shows localization to plasma membrane.Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human testis shows moderate to strong cytoplasmic positivity in subsets of cells in seminiferous ducts.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

2 Publications
NBP1-89953
Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining in human skeletal muscle and tonsil tissues. Corresponding DMD RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Dystrophin Antibody [NBP1-89953] - Staining of human heart muscle shows strong membranous positivity in myocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

3 Publications
NBP1-77461
Immunohistochemistry-Paraffin: RUNX2/CBFA1 Antibody [NBP1-77461] - Vascularization of mineralized cell-laden collagen and interaction with prostate cancer cells. HUVECs formed endothelial networks that were supported by SMA-expressing hMSCs (scale bar: 50m) and were also positive for CD31 (scale bar: 400m). The remainder of hMSCs expressed RUNX2 as a marker for osteogenic differentiation (scale bar: 50m). Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization. <i>Nat Commun</i>  (2019)Immunocytochemistry/Immunofluorescence: RUNX2/CBFA1 Antibody [NBP1-77461] - RUNX2 antibody was tested in HeLa cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

9 Publications
NBP2-34098
Immunocytochemistry/Immunofluorescence: SEPN1 Antibody [NBP2-34098] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.Immunohistochemistry-Paraffin: SEPN1 Antibody [NBP2-34098] - Staining of human lung shows strong cytoplasmic positivity in pneumocytes and macrophages.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

AF3894
Thrombomodulin/BDCA‑3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Mouse Thrombomodulin/BDCA‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3894) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # <a class=    Thrombomodulin/BDCA‑3  was detected in immersion fixed paraffin-embedded sections of human kidney  tissue using Goat Anti-Mouse Thrombomodulin/BDCA‑3 Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF3894) at 1 µg/mL  for 1 hour at room temperature followed by incubation with the Anti-Goat IgG  VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, Flow, IHC

6 Publications
NB300-223
Western Blot: Vimentin Antibody [NB300-223] - Analysis of tissue and cell lysates. Antibody at 1:5000 in red. [1] protein standard (red), [2] rat whole brain lysate, [3] HeLa, [4] SH-SY5Y, [5] HEK293, and [6] NIH-3T3 cell lysates. NB300-223 binds to the vimentin protein showing a single band at ~50 kDa. The blot was simultaneously probed with mouse mAb to MAP2C/D, dilution 1:5000 in green, revealing multiple bands around 280 kDa that correspond to full length MAP2A/2B isotypes, and ~70 kDa bands which are MAP2C/D isotypes. MAP2 isotypes are seen only in extracts containing neuronal lineage cells.Immunocytochemistry/Immunofluorescence: Vimentin Antibody [NB300-223] - Comparative analysis of epithelial and mesenchymal markers expressions. Fluorescence immunocytochemistry staining for E-cadherin (green), N-cadherin (red) and vimentin (cyan) was performed on esophageal cancer cells under static and microfluidic flow conditions at different time points. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/srep38221), licensed under a CC-BY licence.

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     6 Reviews

44 Publications
NB100-56146
Western Blot: MCL1 Antibody [NB100-56146] - analysis of Mcl-1 in A) Ramos and B) ThP-1 lysate using Mcl-1 antibody at 1:2000.Immunohistochemistry-Paraffin: MCL1 Antibody [NB100-56146] - Formalin-fixed paraffin-embedded tissue sections of human diffuse, aggressive Non-Hodgkin's lymphoma (NHL) of B cell lineage stained for Mcl-1 expression using Mcl-1 antibody at 1:2000. A-D, Mcl-1 staining shown as varying magnifications. Hematoxylin-eosin counterstain.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

3 Publications