Chronic Myeloid Leukemia is a clonal disorder caused by malignant transformation of a bone marrow-derived, self-renewing stem cell or progenitor. This leads to a decreased rate of self-destruction and aberrant differentiation causing an accumulation in the organs and bone marrow by these myeloid cells. The development of Chronic Myeloid Leukemia has been associated with many predisposition syndromes that are caused by chromosomal imbalances, DNA repair defects, altered protein synthesis and altered cytokine receptors or signal transduction pathways.
Myeloid Leukemia, Chronic Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Myeloid Leukemia, Chronic below!
For more information on how to use Laverne, please read the How to Guide.
We have 1964 products for the study of Myeloid Leukemia, Chronic that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.