Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Muscular Dystrophy, Oculopharyngeal to be featured!

Blogs

Submit your blog on Muscular Dystrophy, Oculopharyngeal to be featured!

Events

Submit your event on Muscular Dystrophy, Oculopharyngeal to be featured!

Videos

Submit your video on Muscular Dystrophy, Oculopharyngeal to be featured!

Charities

Submit your charity on Muscular Dystrophy, Oculopharyngeal to be featured!

Muscular Dystrophy, Oculopharyngeal: Disease Bioinformatics

Oculopharyngeal Muscular Dystrophy is an inherited disorder that causes muscle weakness. Onset of symptoms of Oculopharyngeal muscular dystrophy begins in adulthood, usually after age 40, with difficulty swallowing. The symptoms worsen over time and can spread to proximal muscles such as the upper legs and hips. Oculopharyngeal muscular dystrophy is caused by a mutation to the PABPN1 gene. There is no cure for Oculopharyngeal muscular dystrophy, but treatment options include surgery to make eating and swallowing easier and gene therapy.

Muscular Dystrophy, Oculopharyngeal Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Muscular Dystrophy, Oculopharyngeal below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 710 products for the study of Muscular Dystrophy, Oculopharyngeal that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-67015
Western Blot: PABPN1 Antibody (JM11-28) [NBP2-67015] - Analysis of PABPN1 on MCF-7 cells lysates using anti-PABPN1 antibody at 1/500 dilution.Immunocytochemistry/Immunofluorescence: PABPN1 Antibody (JM11-28) [NBP2-67015] - Staining PABPN1 in AGS cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

NBP1-89785
Western Blot: Grancalcin Antibody [NBP1-89785] - Analysis using Anti-GCA antibody NBP1-89785 (A) shows similar pattern to independent antibody NBP1-89786 (B).Immunocytochemistry/Immunofluorescence: Grancalcin Antibody [NBP1-89785] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-67817
Western Blot: HspA4 Antibody (SD0861) [NBP2-67817] - Analysis of HSPA4 on Hela cells lysates using anti-HSPA4 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: HspA4 Antibody (SD0861) [NBP2-67817] - Staining HSPA4 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

MAB9096
  MYH7  was detected in immersion fixed paraffin-embedded sections of human heart  using Mouse Anti-Human MYH7 Monoclonal Antibody (Catalog # MAB9096) at  1 µg/mL overnight at 4 °C. Tissue was  stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown;  Catalog # <a class=  Western  blot shows lysates of human skeletal muscle tissue and human heart (atrium)  tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human  MYH7 Monoclonal Antibody (Catalog # MAB9096) followed by HRP-conjugated  Anti-Mouse IgG Secondary Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC

NBP2-38988
Western Blot: HSP40/DNAJB1 Antibody [NBP2-38988] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MGImmunocytochemistry/Immunofluorescence: HSP40/DNAJB1 Antibody [NBP2-38988] - Staining of human cell line A549 shows localization to nucleus. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-88523
Western Blot: SNW1 Antibody [NBP1-88523] - Analysis in mouse cell line NIH-3T3, rat cell line NBT-II and rat cell line pC12.Immunocytochemistry/Immunofluorescence: SNW1 Antibody [NBP1-88523] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
AF3844
Desmin was detected in immersion fixed frozen sections of mouse skeletal muscle using Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=Desmin was detected in immersion fixed paraffin-embedded sections of human heart using 15 µg/mL Human Desmin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3844) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <A class=

Goat Polyclonal
Species Human, Mouse
Applications IHC

     2 Reviews

13 Publications
NBP2-75531
Western Blot: Huntingtin Antibody (JB89-34) [NBP2-75531] - Analysis of Huntingtin on A431 cell using anti-Huntingtin antibody at 1/500 dilution.Immunohistochemistry-Paraffin: Huntingtin Antibody (JB89-34) [NBP2-75531] - Analysis of paraffin-embedded rat brain tissue using anti-Huntingtin antibody. Counter stained with hematoxylin.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

MAB8329
    Lysosomal   alpha ‑Glucosidase was detected in immersion fixed paraffin-embedded  sections of human kidney using Rabbit Anti-Human Lysosomal   alpha ‑Glucosidase Monoclonal Antibody (Catalog # MAB8329) at  3 µg/mL for 1 hour at room temperature followed by  incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody  (Catalog # <a class=    Western  blot shows lysates of human placenta tissue, T47D human breast cancer cell  line, and MCF‑7 human breast cancer cell line. PVDF membrane was  probed with 1 µg/mL of Rabbit Anti-Human Lysosomal   alpha ‑Glucosidase Monoclonal Antibody (Catalog # MAB8329) followed by  HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <a class=

Rabbit Monoclonal
Species Human
Applications WB, IHC

NBP1-51641
Western Blot: Sirtuin 1/SIRT1 Antibody (1F3) [NBP1-51641] - Western blot analysis using SIRT1 mouse mAb against MCF-7 (1), Jurkat (2), Hela (3), HEK293 (4) and A549 (5) cell lysates.Immunocytochemistry/Immunofluorescence: Sirtuin 1/SIRT1 Antibody (1F3) [NBP1-51641] - SIRT1 antibody was tested at 1:10 in Ntera2 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, Flow

3 Publications
NB100-56510
Western Blot: Myogenin Antibody (5FD) [NB100-56510] - Analysis of Myogenin expression in various small-round cell tumor lines. The antibody strongly reacted with a band at ~34 kDa in alveolar rhobdomyosarcoma line (Rh30). Negative cell lines were PFSK-1, EB2, SK-N-SH, and SJSA-1.Immunohistochemistry: Myogenin Antibody (5FD) [NB100-56510] - Human myocytes using NB100-56703 at 2.5 ug/mL. Hematoxylin-eosin counterstain.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

6 Publications
NBP1-88591
Western Blot: PHF5A Antibody [NBP1-88591] - Analysis in HeLa cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-PHF5A antibody. Remaining relative intensity is presented. Loading control: anti-GAPDH.Immunocytochemistry/Immunofluorescence: PHF5A Antibody [NBP1-88591] - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
H00010049-M01
Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - DNAJB6 monoclonal antibody (M01), clone 2C11-C1 Analysis of DNAJB6 expression in Jurkat.Immunocytochemistry/Immunofluorescence: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - Analysis of monoclonal antibody to DNAJB6 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

7 Publications
NB100-56603
Western Blot: Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) [NB100-56603] - Analysis using Azide Free version of NB100-56603. LNCaP cells (passage number 38) were serum-starved for 2 days. After serum starvation, cells were (A) left untreated, (B) treated with 100 ng/ml IGF-1 for 4h, or (C) incubated with 20 um LY294002 for 30 mi

Mouse Monoclonal
Species Human, Mouse, Primate
Applications WB, IHC, IHC-P

12 Publications
NBP2-80461
Western Blot: Glutathione S Transferase kappa 1 Antibody (JE47-38) [NBP2-80461] - Western blot analysis of GSTK1 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1:1000) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5000 dilution was used for 1 hour at room temperature.Positive control:Lane 1: SK-BR-3 cell lysateLane 2: Human skin tissue lysateLane 3: Human placenta tissue lysateImmunohistochemistry-Paraffin: Glutathione S Transferase kappa 1 Antibody (JE47-38) [NBP2-80461] - Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GSTK1 antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:50) for 30 minutes at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Rabbit Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NB100-56370
Western Blot: PUMA Antibody [NB100-56370] - Analysis for Puma a (CT) using NB100-56370 at 1:500 against 30 ug/lane of A) Jurkat and B) NIH 3T3 whole cell lysate.Immunohistochemistry-Paraffin: PUMA Antibody [NB100-56370] - IHC analysis of a formalin fixed paraffin embedded (FFPE) tissue section of a normal mouse lung using PUMA antibody at 1-200 dilution. The signal was developed using HRP-DAB detection and the sections were further counterstained using hematoxylin. The antibody generated a specific diffused cytoplasmic staining in the bronchiolar and alveolar epithelial cells.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

6 Publications
NBP2-49118
Immunohistochemistry-Paraffin: SLCO6A1 Antibody [NBP2-49118] - Staining of human testis shows high expression.Immunohistochemistry-Paraffin: SLCO6A1 Antibody [NBP2-49118] - Staining of human endometrium shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P


Related PTMs

Muscular Dystrophy, Oculopharyngeal has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Muscular Dystrophy, Oculopharyngeal is also known as Dystrophies, Oculopharyngeal Muscular, Dystrophy, Oculopharyngeal Muscular, Muscular Dystrophies, Oculopharyngeal, Oculopharyngeal Dystrophy, Oculopharyngeal Muscular Dystrophies.