Lynch Cancer Family Syndrome 2: Disease Bioinformatics
Lynch syndrome, or lynch cancer, is frequently known as hereditary non-polyposis colon cancer type II (or type B) and is a subtype of colon cancer. Colorectal cancer, commonly referred to as colon cancer, originates in the colon (large intestine) or rectum, typically as adenomatous polyps. It is unknown what causes cancer yet familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC) are thought to increase risk of developing colon cancer. Individuals with lynch syndrome commonly report diagnosis early in life as well as an influx of diagnoses of related cancers such as gastric, ovarian, breast, and endometrial. Lynch syndrome accounts for 3-5% of all colorectal cancer cases. Lynch syndrome is a genetic condition that is caused by mutations on the genes MLH1, MSH2, MSH6, and PMS2. Additionally, increasing age, inflammatory intestinal conditions, nationality, low fiber and high fat diet, diabetes, smoking, alcohol, obesity, and a sedentary lifestyle can contribute to colon cancer's onset. Treatments for colon cancer and lynch syndrome alike include surgery, chemotherapy, radiation therapy, and targeted drug therapy.
Lynch Cancer Family Syndrome 2 Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Lynch Cancer Family Syndrome 2 below!
For more information on how to use Laverne, please read the How to Guide.
We have 1786 products for the study of Lynch Cancer Family Syndrome 2 that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.