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Limb Defect: Disease Bioinformatics

Research of Limb Defect has been linked to Limb Deformities, Congenital, Congenital Abnormality, Teratogenic Effect, Hypoplasia, Congenital Heart Defects. The study of Limb Defect has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Limb Defect include Limb Development, Pathogenesis, Cell Death, Ossification, Limb Morphogenesis. These pathways complement our catalog of research reagents for the study of Limb Defect including antibodies and ELISA kits against SHH, TBX5, TWIST1, NSDHL, WNT.

Limb Defect Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Limb Defect below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 830 products for the study of Limb Defect that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

HOXA13 Antibody (5K0D5)
NBP3-16827
Western Blot: HOXA13 Antibody (5K0D5) [NBP3-16827] - Western blot analysis of extracts of various cell lines, using HOXA13 Rabbit mAb (NBP3-16827) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB

SALL4 Antibody (6E3)
H00057167-M03
Western Blot: SALL4 Antibody (6E3) [H00057167-M03] - Analysis of SALL4 expression in Hela S3 NE (Cat # L013V3).Immunohistochemistry-Paraffin: SALL4 Antibody (6E3) [H00057167-M03] - Analysis of monoclonal antibody to SALL4 on formalin-fixed paraffin-embedded human testis. Antibody concentration 0.2 ug/ml

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ELISA

28 Publications
RAR alpha/NR1B1 Antibody (763)
NB200-322
Western Blot: Retinoic Acid Receptor alpha Antibody (763) [NB200-322] - Analysis of hippocampal lysate showing specific immunolabeling of the ~48k RAR-a protein.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
NIPBL Antibody
NBP1-52168
Immunocytochemistry/Immunofluorescence: NIPBL Antibody [NBP1-52168] - analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing nuclear and cytoplasmic staining. The nuclear staiImmunohistochemistry-Paraffin: NIPBL Antibody [NBP1-52168] - (2ug/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Goat Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
RAR beta/NR1B2 Antibody
NBP1-81776
Immunocytochemistry/Immunofluorescence: RAR beta/NR1B2 Antibody [NBP1-81776] - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.Immunohistochemistry-Paraffin: RAR beta/NR1B2 Antibody [NBP1-81776] - Analysis in human placenta and pancreas tissues using NBP1-81776 antibody. Corresponding RARB RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
TBX5 Antibody
NBP1-83237
Immunohistochemistry-Paraffin: TBX5 Antibody [NBP1-83237] - Staining of human placenta shows moderate nuclear positivity in Hofbauer cells, as well as weaker positivity in trophoblastic cells.Immunohistochemistry-Paraffin: TBX5 Antibody [NBP1-83237] - Staining of human heart muscle shows strong nuclear positivity in cardiomyocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

4 Publications
NSDHL Antibody
NBP1-83306
Immunohistochemistry-Paraffin: NSDHL Antibody [NBP1-83306] - Staining in human epididymis and lymph node tissues using anti-NSDHL antibody. Corresponding NSDHL RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: NSDHL Antibody [NBP1-83306] - Staining of human cerebral cortex, epididymis, lymph node and testis using Anti-NSDHL antibody NBP1-83306 (A) shows similar protein distribution across tissues to independent antibody NBP1-83307 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
PP14/Glycodelin Antibody
NBP1-89781
Western Blot: PP14/Glycodelin Antibody [NBP1-89781] - Analysis in human placenta tissue.Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

SHFM3 Antibody
NBP2-14013
Western Blot: SHFM3 Antibody [NBP2-14013] - Analysis in human cell line MCF-7.Immunocytochemistry/Immunofluorescence: SHFM3 Antibody [NBP2-14013] - Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

SS18L1 Antibody
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

TBX2 Antibody (7G5)
H00006909-M01
Western Blot: TBX2 Antibody (7G5) [H00006909-M01] - TBX2 monoclonal antibody (M01), clone 7G5 Analysis of TBX2 expression in Hela S3 NE.Immunocytochemistry/Immunofluorescence: TBX2 Antibody (7G5) [H00006909-M01] - Analysis of monoclonal antibody to TBX2 on HeLa cell. Antibody concentration 30 ug/ml.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

1 Publication
LRP-5 Antibody
AF6646
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human LRP-5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6646) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB

     1 Review

p63/TP73L Antibody [Unconjugated]
AF1916
p63/TP73L was detected in immersion fixed paraffin-embedded sections of human breast using Goat Anti-Human p63/TP73L Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1916) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=p63/TP73L was detected in immersion fixed SCC-25 human tongue carcinoma cell line using Goat Anti-Human p63/TP73L Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1916) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC, ICC

     4 Reviews

9 Publications
Twist-1 Antibody (10E4E6) - BSA Free
NBP2-37364
Western Blot: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis using TWIST1 mouse mAb against NIH/3T3 (1), JURKAT (2), HELA (3), A549 (4), RAJI (5) and OCM-1 (6) cell lysate.Immunocytochemistry/Immunofluorescence: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis of HeLa cells using TWIST1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

     1 Review

5 Publications
FGF-4 [Unconjugated]
7460-F4/CF


Species Human
Applications BA

2 Publications
FGF-8 [Unconjugated]
423-F8
1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.


Species Human, Mouse
Applications BA

     3 Reviews

55 Publications
Sonic Hedgehog/Shh [Unconjugated]
1845-SH/CF
1 μg/lane of Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.Recombinant Human Sonic Hedgehog/Shh (C24II), N-Terminus (Catalog #<br>1845-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 0.1‑0.4 μg/mL.


Species Human
Applications BA

51 Publications
FBXW11 Antibody
NBP2-56451
Western Blot: FBXW11 Antibody [NBP2-56451] - Analysis in human cell line RT-4 and human cell line U-251 MG.Immunocytochemistry/Immunofluorescence: FBXW11 Antibody [NBP2-56451] - Staining of human cell line SiHa shows localization to nucleoli & vesicles.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF