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Limb Defect: Disease Bioinformatics

Research of Limb Defect has been linked to Limb Deformities, Congenital, Congenital Abnormality, Teratogenic Effect, Hypoplasia, Congenital Heart Defects. The study of Limb Defect has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Limb Defect include Limb Development, Pathogenesis, Cell Death, Ossification, Limb Morphogenesis. These pathways complement our catalog of research reagents for the study of Limb Defect including antibodies and ELISA kits against WNT, CHONDRODYSPLASIA, FGF4, FGF8, HOXA13.

Limb Defect Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Limb Defect below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 389 products for the study of Limb Defect that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

461-SH/CF
1 μg/lane of Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Mouse Sonic Hedgehog/Shh, N-Terminus (Catalog # 461-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The ED<SUB>50</SUB> for this effect is 0.6‑3 μg/mL.


Species Mouse

24 Publications
NBP1-83237
Immunohistochemistry-Paraffin: TBX5 Antibody [NBP1-83237] - Staining of human placenta shows moderate nuclear positivity in Hofbauer cells, as well as weaker positivity in trophoblastic cells.Immunohistochemistry-Paraffin: TBX5 Antibody [NBP1-83237] - Staining of human heart muscle shows strong nuclear positivity in cardiomyocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

2 Publications
NBP2-37364
Western Blot: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis using TWIST1 mouse mAb against NIH/3T3 (1), JURKAT (2), HELA (3), A549 (4), RAJI (5) and OCM-1 (6) cell lysate.Immunocytochemistry: Twist-1 Antibody (10E4E6) [NBP2-37364] - Analysis of Hela cells using TWIST1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

NBP1-83306
Western Blot: NSDHL Antibody [NBP1-83306] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human cell line A-431 Lane 5: Human liver tissueImmunocytochemistry/Immunofluorescence: NSDHL Antibody [NBP1-83306] - Staining of human cell line A-431 shows localization to endoplasmic reticulum & lipid droplets.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP2-58808
Western Blot: HOXA13 Antibody [NBP2-58808] - Western blot analysis in human cell line RT-4.Immunocytochemistry/Immunofluorescence: HOXA13 Antibody [NBP2-58808] - Staining of human cell line U-2 OS shows localization to nucleoplasm & intermediate filaments.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP2-14013
Western Blot: SHFM3 Antibody [NBP2-14013] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: SHFM3 Antibody [NBP2-14013] - Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-85110
Immunocytochemistry/Immunofluorescence: NIPBL Antibody [NBP1-85110] - Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.Immunohistochemistry: NIPBL Antibody [NBP1-85110] - Staining of human small intestine shows moderate nuclear positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IF

1 Publication
AF842
Western blot shows lysates of human uterus tissue and human placenta tissue. PVDF membrane was probed with 0.2 µg/mL of Goat Anti-Human PP14/Glycodelin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF842) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB

2 Publications
NBP2-33090

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

423-F8/CF
1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.Recombinant Human/Mouse FGF-8b (Catalog # 423-F8/CF) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.


Species Human, Mouse

33 Publications
NBP1-81776
Western Blot: RAR beta/NR1B2 Antibody [NBP1-81776] - Analysis in control (vector only transfected HEK293T lysate) and rARB over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: RAR beta/NR1B2 Antibody [NBP1-81776] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
H00057167-M03
Western Blot: SALL4 Antibody (6E3) [H00057167-M03] - Analysis of SALL4 expression in Hela S3 NE (Cat # L013V3).Immunohistochemistry-Paraffin: SALL4 Antibody (6E3) [H00057167-M03] - Analysis of monoclonal antibody to SALL4 on formalin-fixed paraffin-embedded human testis. Antibody concentration 0.2 ug/ml

Mouse Monoclonal
Species Human, Mouse
Applications WB, ChIP, ELISA

20 Publications
NBP2-16454
Western Blot: FBXW11 Antibody [NBP2-16454] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7. 5% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: FBXW11 Antibody [NBP2-16454] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: FBXW11 protein stained by FBXW11 antibody diluted at 1:500. Blue: Hoechst 33343 staining.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

235-F4/CF
1 μg/lane of Recombinant Human FGF-4 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 16 kDa.Recombinant Human FGF-4 (Catalog # 235‑F4/CF) stimulates cell proliferation of the NR6R‑3T3 mouse fibroblast cell line. The ED<SUB>50</SUB> for this effect is 0.25‑1.25 ng/mL.


Species Human

29 Publications
NB200-322
Western Blot: Retinoic Acid Receptor alpha Antibody (763) [NB200-322] - Analysis of hippocampal lysate showing specific immunolabeling of the ~48k RAR-a protein.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC-Fr

     1 Review

1 Publication
NB100-1886
Western Blot: LRP-5 Antibody [NB100-1886] - (1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: LRP-5 Antibody [NB100-1886] - (2ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-89459
Immunocytochemistry/Immunofluorescence: TBX2 Antibody [NBP1-89459] - Staining of human cell line MCF7 shows localization to nucleoplasm.Immunohistochemistry-Paraffin: TBX2 Antibody [NBP1-89459] - Staining of human stomach shows strong nuclear and cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

2 Publications