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Keratoderma, Palmoplantar, Diffuse: Disease Bioinformatics

Research of Keratoderma, Palmoplantar, Diffuse has been linked to Palmoplantar Keratosis, Esophageal Neoplasms, Malignant Neoplasms, Carcinoma, Malignant Neoplasm Of Esophagus. The study of Keratoderma, Palmoplantar, Diffuse has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Keratoderma, Palmoplantar, Diffuse include Keratinization, Pathogenesis, Pigmentation, Localization, Senescence. These pathways complement our catalog of research reagents for the study of Keratoderma, Palmoplantar, Diffuse including antibodies and ELISA kits against KRT1, RHBDF2, GJB2, KRT16, KERATIN 9.

Keratoderma, Palmoplantar, Diffuse Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Keratoderma, Palmoplantar, Diffuse below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1437 products for the study of Keratoderma, Palmoplantar, Diffuse that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-29429
Dual RNAscope ISH-IHC: Cytokeratin, pan Antibody (AE-1/AE-3) [NBP2-29429] - Formalin-fixed paraffin-embedded tissue sections of human metastatic tonsil were probed for Pan Cytokeratin mRNA (ACD RNAScope probe, catalog # 310221; Fast Red chromogen, ACD catalog # 322500). Adjacent tissue section was processes for immunohistochemistry using mouse monoclonal  (Novus catalog # NBP2-29429) at 0.3ug/mL for 1 hour at room temperature followed by incubation with the anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue).Immunocytochemistry/Immunofluorescence: Cytokeratin, pan Antibody (AE-1/AE-3) [NBP2-29429] - MCF-7 cells stained with Biotin conjugated version of pan Cytokeratin antibody and SAv-A488. A) SAv-A488 only at a dilution of 1:500, B) pan CK at a dilution of 1:200, C) pan CK at a dilution of 1:400, D) pan CK at a dilution of 1:800. Image from verified customer review.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

21 Publications
MAB10048
    Western  blot shows lysates of LoVo human colorectal adenocarcinoma cell line and  MCF‑7 human breast cancer cell line. PVDF membrane was probed with  2 µg/mL of Mouse Anti-Human iRHOM2/RHBDF2 Monoclonal Antibody  (Catalog # MAB10048) followed by HRP-conjugated Anti-Mouse IgG Secondary  Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB

NB100-57840
Western Blot: Connexin 26/GJB2 Antibody [NB100-57840] - Staining of Mouse Brain lysate with antibody at 0.01 ug/mL (A), Mouse Heart (B) and Rat Heart (C) lysate with antibody at 0.5 ug/mL (35 ug protein in RIPA buffer). Detected by chemiluminescence.Flow Cytometry: Connexin 26/GJB2 Antibody [NB100-57840] - Flow cytometric analysis of paraformaldehyde fixed HepG2 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, PEP-ELISA

1 Publication
NBP2-67559
Western Blot: Cytokeratin 16 Antibody (SC52-09) [NBP2-67559] - Analysis of Cytokeratin 16 on human skin lysates using anti-Cytokeratin 16 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: Cytokeratin 16 Antibody (SC52-09) [NBP2-67559] - Staining Cytokeratin 16 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human
Applications WB, Flow, ICC/IF

AF2498

Goat Polyclonal
Species Mouse
Applications WB, IP

2 Publications
NBP1-49879
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP1-49879] - Paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

2 Publications
H00114757-M02
Western Blot: Cytoglobin Antibody (1A1) [H00114757-M02] - Analysis of CYGB expression in transfected 293T cell line by CYGB monoclonal antibody (M02), clone 1A1.Lane 1: CYGB transfected lysate(21 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: Cytoglobin Antibody (1A1) [H00114757-M02] - Analysis of monoclonal antibody to CYGB on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, ICC/IF

5 Publications
NBP2-50599
Flow Cytometry: EGFR Antibody (DH8.3) - EGFRvIII [NBP2-50599] - An intracellular stain was performed on A431 cells with EGFR [DH8.3] Antibody NBP2-50599R (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to DyLight 550.Flow Cytometry: EGFR Antibody (DH8.3) - EGFRvIII [NBP2-50599] - An intracellular stain was performed on A431 cells with EGFR [DH8.3] Antibody NBP2-50599AF700 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 700.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

4 Publications
NBP2-37940
Immunocytochemistry/Immunofluorescence: EVPL Antibody [NBP2-37940] - Staining of human cell line MCF7 shows localization to intermediate filaments. Antibody staining is shown in green. Immunohistochemistry-Paraffin: EVPL Antibody [NBP2-37940] - Staining in human skin and skeletal muscle tissues using anti-EVPL antibody. Corresponding EVPL RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

236-EG
1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE  and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa.Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 20‑100 pg/mL.


Species Human

452 Publications
AF4479
SLURP1 was detected in immersion fixed paraffin-embedded sections of human skin using Sheep Anti-Human SLURP1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4479) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications IHC

NBP1-33610
Immunohistochemistry: Loricrin Antibody [NBP1-33610] - Prominent differences in the expressions of innate immune and barrier molecules between sebaceous gland poor (SGR) and sebaceous gland rich (SGP) skin regions. Representative images for immunostaining and quantification of epidermal levels of LOR in SGP and SGR skin sections. Images of negative control stainings are shown in the bottom left corner of SGP immunostainings. Size bars=100um. The graphs show the mean +/- SEM of measured protein levels (*p<0.05; **p<0.01; ***p<0.001, as determined by Mann-Whitney U-test). Image collected and cropped by CiteAb from the following publication (frontiersin.org/articles/10.3389/fimmu.2018.00424/full), licensed under a CC-BY licence.Western Blot: Loricrin Antibody [NBP1-33610] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Loricrin antibody [N1], N-term diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

     3 Reviews

2 Publications
NBP2-67810
Immunohistochemistry-Paraffin: KRT9 Antibody (SD201-09) [NBP2-67810] - Analysis of mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-26245
TIRAP (TLR2 and TLR4) Inhibitor Peptide [NBP2-26245] - TLR2 acts through formation of heterodimer complexes with TLR1 or TLR6. HEK 293 endogenously expresses TLR1 and TLR6, so that the TLR2 reporter cell line can response to both Pam3CSK4 (TLR2/TLR1 specific ligand) and MALP-2 (TLR2/TLR6 specific ligand). The TLR2 / TLR4 inhibitor specifically inhibits TLR2/TLR1 receptor complex activity in a dose-response manner but exhibited no or little effect on TLR2/TLR6 receptor complex activity.TIRAP (TLR2 and TLR4) Inhibitor Peptide [NBP2-26245] - The TLR4 reporter cell line responds to LPS. The TLR2 / TLR4 inhibitor specifically inhibits TLR4 activation upon LPS stimulation in a dose-response manner.


Species Human, Mouse

5 Publications
NBP2-75563
Western Blot: MAL Antibody (B5-G3) [NBP2-75563] - Analysis of MAL on mouse kidney (1) and mouse lymphatic vessels (2) tissue lysate using anti-MAL antibody at 1/1,000 dilution.Immunohistochemistry-Paraffin: MAL Antibody (B5-G3) [NBP2-75563] - Analysis of paraffin-embedded rat kidney tissue using anti-MAL antibody. Counter stained with hematoxylin.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

NBP1-88498
Western Blot: Mkl1 Antibody [NBP1-88498] - Analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunocytochemistry/Immunofluorescence: Mkl1 Antibody [NBP1-88498] - Staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

6 Publications
NBP1-90824
Western Blot: CD77 Synthase Antibody [NBP1-90824] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY402588)Immunocytochemistry/Immunofluorescence: CD77 Synthase Antibody [NBP1-90824] - Staining of human cell line MCF7 shows localization to mitochondria. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF


Related Genes

Keratoderma, Palmoplantar, Diffuse has been researched against:

Related PTMs

Keratoderma, Palmoplantar, Diffuse has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Keratoderma, Palmoplantar, Diffuse is also known as Tylosis Palmaris Et Plantaris, Unna-thost Disease, Unna-thost Syndrome, Diffuse Palmoplantar Keratoderma, Thost Unna Syndrome.