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Iron Overload: Disease Bioinformatics

Research of Iron Overload has been linked to Hemochromatosis, Thalassemia, Anemia, Beta Thalassemia, Hereditary Hemochromatosis. The study of Iron Overload has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Iron Overload include Pathogenesis, Transport, Excretion, Secretion, Localization. These pathways complement our catalog of research reagents for the study of Iron Overload including antibodies and ELISA kits against HFE, TF, HAMP, HFE2, EPO.

Iron Overload Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Iron Overload below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1646 products for the study of Iron Overload that can be applied to Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Ceruloplasmin Antibody (6C3K9)
NBP3-15868
Western Blot: Ceruloplasmin Antibody (6C3K9) [NBP3-15868] - Analysis of extracts of various cell lines, using Ceruloplasmin antibody (NBP3-15868) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.Immunohistochemistry: Ceruloplasmin Antibody (6C3K9) [NBP3-15868] - Immunofluorescence analysis of mouse liver using Ceruloplasmin Rabbit mAb (NBP3-15868) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

HFE Antibody (1G12)
H00003077-M01
Western Blot: HFE Antibody (1G12) [H00003077-M01] - Analysis of HFE expression in transfected 293T cell line by HFE monoclonal antibody (M01), clone 1G12.Lane 1: HFE transfected lysate(40.1 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: HFE Antibody (1G12) [H00003077-M01] - Analysis of monoclonal antibody to HFE on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     2 Reviews

1 Publication
Thromboxane synthase Antibody (OTI2C1)
NBP2-02710
Western Blot: Thromboxane synthase Antibody (2C1) [NBP2-02710] Analysis of extracts (35ug) from 9 different cell lines by using anti-Thromboxane synthase monoclonal antibody.Immunocytochemistry/Immunofluorescence: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Thromboxane synthase.

Mouse Monoclonal
Species Human, Rat
Applications WB, Flow, ICC/IF

1 Publication
Sialin/SLC17A5 Antibody
NBP2-20383
Western Blot: SLC17A5 Antibody [NBP2-20383] - Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SLC17A5 Antibody [NBP2-20383] - Sample: HepG2 cells were fixed in -20C 100% MeOH for 5 min. Green: SLC17A5 protein stained by SLC17A5 antibody diluted at 1:500. Blue: Hoechst 33343 staining.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

Ferroportin/SLC40A1 Antibody - BSA Free
NBP1-21502
Western Blot: Ferroportin/SLC40A1 Antibody - BSA Free [NBP1-21502] - Mouse Ferroportin/SLC40A1, 5-aminolevulinic acid synthase (ALAS), and ferritin light chain (FLC) proteins are increased in sickle mice overexpressing human wt-FHC. Proteins of subcellular fractions isolated from livers of wt-, ms-, and LRS-treated mice (n = 4) were run on a western blot (30 ug protein/lane) and immunostained for microsomal ferroportin. Image collected and cropped by CiteAb from the following publication (http://journal.frontiersin.org/article/10.3389/fphar.2014.00079/abstract), licensed under a CC-BY licence.Immunocytochemistry/Immunofluorescence: Ferroportin/SLC40A1 Antibody - BSA Free [NBP1-21502] - HepG2 cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with Ferroportin/SLC40A1 Antibody at 5.0 ug/ml overnight at 4C and detected with an anti-rabbit DyLight 488 (green) at a 1:500 dilution. Alpha tubulin (DM1A) [NB100-690] was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse DyLight 550 (red) at a 1:500 dilution. Nuclei were counterstained with DAPI (blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     7 Reviews

141 Publications
RGM-C/Hemojuvelin Antibody
AF3634

Goat Polyclonal
Species Mouse
Applications WB

5 Publications
Insulin Antibody (182410) [Unconjugated]
MAB1417
Insulin was detected in immersion fixed beta TC‑6 mouse beta cell insulinoma cell line using Human/Mouse/Bovine Insulin Monoclonal Antibody (Catalog # MAB1417) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=Insulin was detected in immersion fixed paraffin-embedded sections of human pancreas using Rat Anti-Human/Mouse/Bovine Insulin Monoclonal Antibody (Catalog # MAB1417) at 0.5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rat IgG VisUCyte™ HRP Polymer Antibody (<a class=

Rat Monoclonal
Species Human, Mouse, Bovine
Applications IHC, CyTOF-ready, ICC

15 Publications
Erythropoietin/EPO [HRP]
MEP00B
Erythropoietin/EPO [HRP] Erythropoietin/EPO [HRP]


Species Mouse
Applications ELISA

99 Publications
Holo-Transferrin [Unconjugated]
2914-HT


Species Human
Applications BA

37 Publications
IL-6 [HRP]
D6050
IL-6 [HRP] IL-6 [HRP]


Species Human
Applications ELISA

718 Publications
Hepcidin Antimicrobial Peptide [HRP]
DHP250
Hepcidin Antimicrobial Peptide [HRP] Hepcidin Antimicrobial Peptide [HRP]


Species Human
Applications ELISA

11 Publications
Cav1.2 Antibody (S57)
NBP1-22439
Western Blot: Cav1.2 Antibody (S57) [NBP1-22439] - Western Blot analysis of Hamster T-CHO cell lysate showing detection of CaV1.2 Calcium Channel protein using Mouse Anti-CaV1.2 Calcium Channel Monoclonal Antibody, Clone S57 (NBP1-22439). Primary Antibody: Mouse Anti-CaV1.2 Calcium Channel Monoclonal Antibody (NBP1-22439) at 1:1000.Immunocytochemistry/Immunofluorescence: Cav1.2 Antibody (S57) [NBP1-22439] - Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Cav1.2 Monoclonal Antibody, Clone S57 (NBP1-22439). Tissue: Neuroblastoma cells (SH-SY5Y). Species: Human. Fixation: 4% PFA for 15 min. Primary Antibody: Mouse Anti-Cav1.2 Monoclonal Antibody (NBP1-22439) at 1:50 for overnight at 4C with slow rocking. Secondary Antibody: AlexaFluor 488 at 1:1000 for 1 hour at RT. Counterstain: Phalloidin-iFluor 647 (red) F-Actin stain; Hoechst (blue) nuclear stain at 1:800, 1.6mM for 20 min at RT. (A) Hoechst (blue) nuclear stain. (B) Phalloidin-iFluor 647 (red) F-Actin stain. (C) Cav1.2 Antibody (D) Composite.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
TfR2 Antibody (353810) [Unconjugated]
MAB31202
Western blot shows lysates of K562 human chronic myelogenous leukemia cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human TfR2 Monoclonal Antibody (Catalog # MAB31202) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (<a class=NoLineLink href=K562 human myelogenous leukemia cell line was stained with Mouse Anti-Human TfR2 Monoclonal Antibody (Catalog # MAB31202, filled histogram) or isotype control antibody (<a class=NoLineLink href=

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

Recombinant Human Blood group H inhibitor GST (N-Term) Protein
H00002523-P01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human
Applications WB, ELISA, PA

NRAMP2/SLC11A2/DMT1 Antibody (4C6)
H00004891-M01
Immunohistochemistry-Paraffin: NRAMP2/SLC11A2/DMT1 Antibody (4C6) [H00004891-M01] - Immunohistochemistry of iron handling proteins in healthy kidney. Representatives images of ZIP8 (a), ZIP14 (b), divalent metal transporter 1 (DMT1; c), L-ferritin (d), H-ferritin (e), and ferroportin (f) staining in healthy kidney. Renal structures indicated as glomerulus (g), proximal tubule (PT), distal tubule (DT). Scale bar 20uM. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41598-018-27107-8) licensed under a CC-BY licence.Immunohistochemistry-Paraffin: NRAMP2/SLC11A2/DMT1 Antibody (4C6) [H00004891-M01] - Analysis of monoclonal antibody to SLC11A2 on formalin-fixed paraffin-embedded human endometrium cancer. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, ELISA, ICC/IF

9 Publications
Thymidylate Synthase Antibody (TYMS/1884) - Azide and BSA Free
NBP3-08882
Western Blot: Thymidylate Synthase Antibody (TYMS/1884) [NBP3-08882] - Western Blot Analysis of human HeLa cell lysate using Thymidylate Synthase Mouse Monoclonal Antibody (TYMS/1884).Immunocytochemistry/Immunofluorescence: Thymidylate Synthase Antibody (TYMS/1884) [NBP3-08882] - Immunofluorescence Analysis of PFA-fixed Ramos cells labeling PU.1 with Thymidylate Synthase Mouse Monoclonal Antibody (TYMS/1884) followed by goat anti- Mouse IgG-CF488 (Green). Membrane is labeled with Phalloidin (Red).

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF