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Irido-corneal Dysgenesis: Disease Bioinformatics

Research of Irido-corneal Dysgenesis has been linked to Congenital Abnormality, Glaucoma, Eye Abnormalities, Corneal Diseases, Cataract. The study of Irido-corneal Dysgenesis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Irido-corneal Dysgenesis include Eye Development, Pathogenesis, Cell Migration, Cell Adhesion, Neural Crest Cell Migration. These pathways complement our catalog of research reagents for the study of Irido-corneal Dysgenesis including antibodies and ELISA kits against APHAKIA, STRABISMUS, TRANSFORMING GROWTH FACTOR ALPHA, HAZE, ABCC6.

Irido-corneal Dysgenesis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Irido-corneal Dysgenesis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 478 products for the study of Irido-corneal Dysgenesis that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

H00005308-M01
Immunocytochemistry/Immunofluorescence: PITX2 Antibody (2G6) [H00005308-M01] - Analysis of monoclonal antibody to PITX2 on HeLa cell. Antibody concentration 10 ug/ml.ELISA: PITX2 Antibody (2G6) [H00005308-M01] - Detection limit for recombinant GST tagged PITX2 is approximately 0.03ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

3 Publications
NB100-1268
Western Blot: FoxC1 Antibody [NB100-1268] - HEK293 lysate (10ug protein in RIPA buffer) over expressing Human FOXC1 with DYKDDDDK tag probed with FOXC1 Antibody (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with FOXC1 Antibody (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: FoxC1 Antibody [NB100-1268] - Staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human, Zebrafish
Applications WB, ChIP, ICC/IF

9 Publications
NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry/Immunofluorescence: Pax6 Antibody [NB300-750] - Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with a PAX6 polyclonal antibody at a dilution of 1:400 for 30 minutes at room temperature. F-Actin (red) was stained with DyLight 554 Phalloidin were stained with Hoechst 33342 dye.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IP

     4 Reviews

2 Publications
NBP2-24722
Western Blot: CYP1B1 Antibody [NBP2-24722] - Analysis of CYP1B1 in human brain lysate in the 1) absence and 2) presence of immunizing peptide using this antibody at 1 ug/ml.Immunohistochemistry-Paraffin: CYP1B1 Antibody [NBP2-24722] - Analysis of human adrenal using this antibody at 10 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB, IHC-P

     1 Review

2 Publications
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

H00002301-R01
Other FOXE3 RNAi


Species Human

NBP1-92274
Western Blot: PITX3 Antibody [NBP1-92274] - Analysis in human cell line RH-30.Immunohistochemistry-Paraffin: PITX3 Antibody [NBP1-92274] - Staining of human cerebellum shows strong cytoplasmic positivity, with a granular pattern in Purkinje cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB120-6586
Immunohistochemistry-Paraffin: Collagen IV alpha 1 Antibody [NB120-6586] - Analysis of Biotin conjugate of NB120-6586. Collagen IV antibody 1:400, 45 min RT showed strong staining in FFPE sections of human kidney (Left) with strong red staining observed in glomeruli and liver (Right) with strong staining in sinusoids. Staining fImmunohistochemistry-Paraffin: Collagen IV alpha 1 Antibody [NB120-6586] - Analysis of Collagen IV in various paraffin embedded human tissues. Image courtesy of product review submitted by Daniel Pirici.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

     3 Reviews

6 Publications
NBP2-24551
Western Blot: c-Maf Antibody [NBP2-24551] - Analysis of Lysate from human brain in the 1) absence, 2) presence of immunizing peptide, 3) mouse brain and 4) rat brain probed at 3 ug/ml.Immunohistochemistry-Paraffin: c-Maf Antibody [NBP2-24551] - Staining of Human placenta probed with c-maf antibody at 10 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     2 Reviews

2 Publications
NBP1-88950
Western Blot: B3GALTL Antibody [NBP1-88950] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: B3GALTL Antibody [NBP1-88950] - Staining of human cerebellum shows strong cytoplasmic and nuclear positivity in Purkinje cells and cells in the molecular layer. Cells in the granular layer are moderately

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-37576
Western Blot: c-jun Antibody (5B1) [NBP2-37576] - Western blot analysis using c-Jun mouse mAb against NIH/3T3 (1) and Cos7 (2) cell lysate.Immunocytochemistry/Immunofluorescence: c-jun Antibody (5B1) [NBP2-37576] - Immunofluorescence analysis of PC-2 cells using c-Jun mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Primate
Applications WB, ELISA, Flow

314-BP/CF
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

237 Publications
NB100-91761
Western Blot: Factor VIII Antibody [NB100-91761] - WB detection of Factor VIII protein in extracts from human umbilical vein endothelial cells (HUVECs). Immunocytochemistry/Immunofluorescence: Factor VIII Antibody [NB100-91761] - Factor VIII antibody was tested 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
NBP1-42342

Rat Monoclonal
Species Human
Applications WB, Flow, IHC

1 Publication
NBP2-50037
Western Blot: c-Fos Antibody (2H2) [NBP2-50037] - Top panel: Analysis of c-Fos expression in HeLa cells using NBP2-50037. Lane 1: HeLa cells were serum-starved for 36 hours.  Lane 2: Serum-starved HeLa cells were stimulated with 20% FBS (fetal bovine serum) for 2 hours. NBP2-50037 recognizes bands in the range of 50-65 kDa, which represent multiple forms of c-Fos. Serum starvation attenuates c-Fos expression, while 20% FBS strongly stimulates c-Fos expression.  Bottom panel: Blot was stripped and probed with monoclonal antibody against GAPDH (NB300-221) used as loading control.Immunocytochemistry/Immunofluorescence: c-Fos Antibody (2H2) [NBP2-50037] - Left: NBP2-50037 staining (green) in HeLa cells, which were treated with serum-starvation for 36 hrs, followed by 2 hrs 20% FBS stimulation (bottom), or PBS treatment (top). Green c-Fos staining only localizes in the nuclei of stimulated cells, but not in un-stimulated cells. Cells are counter-stained with chicken pAb against Vimentin (NB300-223, red). Blue shows DAPI staining of nucleus. Middle: Mouse brain section (45 uM; fixed by transcardial perfusion with 4% PFA) labeled with NBP2-50037 using a standard HRP-DAB staining technique. Cells expressing c-Fos show dark color in nucleus. Right: Mouse cortical section labeled with NBP2-50037 (red) and rabbit polyclonal anti-NeuN (NBP1-92716, green) using IF confocal. Neurons positive for c-Fos and RBFOX3/NeuN appear to be yellow. Inset shows an enlarged image of NBP2-50037 staining. Nuclei are labeled with Dapi (blue).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

     1 Review

NLS3593
Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS3593] - Analysis of anti-GPR48 / LGR4 antibody with human lung, adenocarcinoma.Immunohistochemistry-Paraffin: Lgr4/GPR48 Antibody [NLS3593] - Analysis of anti-GPR48 / LGR4 antibody with brain, neurons and glia at 7 ug/ml.

Rabbit Polyclonal
Species Human, Porcine, Bovine
Applications IHC-P

     1 Review