Epilepsy is defined as a diverse set of neurological disorders characterized by seizures. These seizures occur due to abnormal electrical activity in the brain. Factors that may lead to epilepsy include, but are not limited to, brain trauma, gene mutations, strokes, brain cancer, and extensive drug and alcohol use. Seizures occur due to a large release of glutamate, which causes a spread of excitation throughout the brain, which propagates the electrical signal and can lead to neuronal death. Intractable epilepsy, otherwise known as refractory epilepsy, is related to tuberous sclerosis as well as generalized epilepsy with febrile seizures. The HSPBAP1 gene is associated with this disease. Intractable epilepsy is categorized by a difficulty controlling seizures, which can stem from seizures that are too strong to be controlled by medication, or by an intolerance of medication. About 50 million people have epilepsy, with 80% of that population located in developing countries. It is possible to control epilepsy with medicine, but many cases, especially cases of intractable epilepsy, may require surgery in order to relieve symptoms.
Intractable Epilepsy Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Intractable Epilepsy below!
For more information on how to use Laverne, please read the How to Guide.
We have 1111 products for the study of Intractable Epilepsy that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.