Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Hyperpigmentation to be featured!

Blogs

Submit your blog on Hyperpigmentation to be featured!

Events

Submit your event on Hyperpigmentation to be featured!

Videos

Submit your video on Hyperpigmentation to be featured!

Charities

Submit your charity on Hyperpigmentation to be featured!

Hyperpigmentation: Disease Bioinformatics

Research of Hyperpigmentation has been linked to Pigmentation Disorders, Dermatologic Disorders, Hypopigmentation Disorder, Erythema, Cicatrix. The study of Hyperpigmentation has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hyperpigmentation include Pigmentation, Pathogenesis, Aging, Secretion, Hypersensitivity. These pathways complement our catalog of research reagents for the study of Hyperpigmentation including antibodies and ELISA kits against MOTTLED, DOPACHROME ISOMERASE, HAIRLESS, C2, DCT.

Hyperpigmentation Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hyperpigmentation below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1944 products for the study of Hyperpigmentation that can be applied to Chromatin Immunoprecipitation, Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-25238
Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (20X) stained with Tyrosinase Ab (T311).Immunohistochemistry-Paraffin: Tyrosinase Antibody (T311) [NBP2-25238] - Formalin-paraffin melanoma (10X) stained with Tyrosinase Ab (T311).

Mouse Monoclonal
Species Human
Applications Flow, ICC/IF, IHC-P

NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Western blot analysis of POMC using NB100-1533 at 0.01ug/ml in NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Analysis in human Anterior Pituitary Gland shows vesilulate staining in glandular cells.

Goat Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

7 Publications
255-SC
1 μg/lane of Recombinant Human SCF/c-kit Ligand was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 19 kDa.Recombinant Human SCF/c-kit Ligand (Catalog # 255-SC) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<SUB>50</SUB> for this effect is 1-5 ng/mL.


Species Human

     2 Reviews

116 Publications
MAB1936

Mouse Monoclonal
Species Human
Applications WB, IP

1 Publication
NB100-56561
Western Blot: MITF Antibody (21D1418) [NB100-56561] - Analysis of A375 lysate using MITF antibody at 4 ug/ml.Western Blot: MITF Antibody (21D1418) [NB100-56561] - Western blot analysis of HeLa lysate (35ug per lane, RIPA buffer) using MiTF antibody (NB100-56561) at 0.1ug/ml. Band detected at ~60kDa. (Expected MW of 58.2kDa according to NP_937802.1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB

1 Publication
NBP2-26504
In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB as shown by EMSA. U266 cells were treated with 100 uM of control or NBD peptide for different time periods. Nuclear extracts were isolated and checked for NF-kB-DNA binding activity.In vivo assay: IKK gamma Inhibitor Peptide Set [NBP2-26504] - NBD peptide blocks constitutive NF-kB activation in human multiple myeloma cells. U266 cells were treated with 100 uM of control (A & B) or NBD peptide (C & D) for 12 hr, cytospun, plated on glass slides, air dried for 1 hr at room temperature and fixed with cold acetone. Slides were blocked with 5% normal goat serum for 1 hr and then incubated with rabbit polyclonal anti-human p65 antibody (A & C) followed by Ig-Alexa 594 second step. In control peptide treated cells, p65 translocates to nucleus (A), whereas NBD peptide prevents translocation of p65 into the nucleus (C). B & D: Nuclear staining with DNA binding dye.


Species Human, Mouse, Rat

22 Publications
NBP1-88370
Western Blot: TYRP1 Antibody [NBP1-88370] - Analysis in human cell line SK-MEL-30.Immunocytochemistry/Immunofluorescence: TYRP1 Antibody [NBP1-88370] - Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-86892
Western Blot: TRP2 Antibody [NBP1-86892] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: TRP2 Antibody [NBP1-86892] - Staining of human skeletal muscle shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
AF1356
Western blot shows lysates of MO7e human megakaryocytic leukemic cell line, P815 mouse mastocytoma cell line, and MC/9‑2 mouse mast cell line. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=CD117/c-kit was detected in immersion fixed frozen sections of mouse embryo using Goat Anti-Human/Mouse CD117/c-kit Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1356) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     8 Reviews

27 Publications
NBP1-56853
Western Blot: RPE Antibody [NBP1-56853] - Human Muscle lysate, concentration 0.2-1 ug/ml.Immunocytochemistry/Immunofluorescence: RPE Antibody [NBP1-56853] - Antibody  0 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver  Observed Staining: Cytoplasm but only in connective tissue cells in the interlobular septum, very low tissue distribution Primary Antibody

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-74413
Western Blot: ER alpha/NR3A1 Antibody (EVG F9) [NB100-74413] - Analysis of various whole cell lysates.Immunocytochemistry/Immunofluorescence: ER alpha/NR3A1 Antibody (EVG F9) [NB100-74413] - Analysis of Estrogen Receptor alpha using Anti-Estrogen Receptor alpha Monoclonal Antibody (EVG F9) shows staining in U251 Cells. Estrogen Receptor alpha staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Estrogen Receptor alpha at a dilution of 1:200 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ICC/IF, IHC

AF1195
Epiregulin was detected in immersion fixed paraffin-embedded sections of human skin using Goat Anti-Human Epiregulin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1195) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <a class=Recombinant Human Epiregulin (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC, Neut

6 Publications
NBP1-30151
Immunocytochemistry/Immunofluorescence: MART-1 / Melan-A Antibody (A19-P) [NBP1-30151] - Staining of human hair follicle culture using NBP1-30151 at a dilution of 1:200. Image provided by Dr. H. Locher of Leiden University Medical Center.Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (A19-P) [NBP1-30151] - Formalin fixed, paraffin embedded human tissue (4 um section) stained with anti - Melan A  monospecific clonal antibody.

Rabbit Monoclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

     3 Reviews

5 Publications
NBP2-22194
Western Blot: Cytokeratin 5 Antibody (2C2) [NBP2-22194] - Western blot analysis using Cytokeratin 5 mouse mAb against A431 (1), MCF-7 (2), HeLa (3), HepG2 (4), 3T3-L1 (5), and COS-7 (6) cell lysate.Immunocytochemistry/Immunofluorescence: Cytokeratin 5 Antibody (2C2) [NBP2-22194] - Immunofluorescence analysis of HeLa  cells. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human, Mouse, Monkey
Applications WB, ELISA, Flow

NBP2-34270
Immunohistochemistry-Paraffin: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Formalin-fixed, paraffin-embedded prostate stained with Cytokeratin 14 Monoclonal Antibody (LL002).Flow Cytometry: Cytokeratin 14 Antibody (LL002) [NBP2-34270] - Flow Cytometry: Cytokeratin 14 Antibody (LL002) [Alexa Fluor® 488] [NBP2-34675AF488] - An intracellular stain was performed on HeLa cells with Cytokeratin 14 Antibody (LL002) NBP2-34675AF488 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 10 ug/mL for 30 minutes. Both antibodies were conjugated to Alexa Fluor 488. Image using the Alexa Fluor 488 form of this antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews


Related Genes

Hyperpigmentation has been researched against:

Related PTMs

Hyperpigmentation has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hyperpigmentation is also known as Hypermelanoses, Hypermelanosis, Hyperpigmentation Disorder, Hyperpigmentation Disorders, Hyperpigmentation Of Skin.