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Hyperlipoproteinemia Type Iib: Disease Bioinformatics

Research of Hyperlipoproteinemia Type Iib has been linked to Hypercholesterolemia, Hypercholesterolemia, Familial, Coronary Heart Disease, Atherosclerosis, Hyperlipoproteinemias. The study of Hyperlipoproteinemia Type Iib has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hyperlipoproteinemia Type Iib include Transport, Pathogenesis, Secretion, Excretion, Platelet Aggregation. These pathways complement our catalog of research reagents for the study of Hyperlipoproteinemia Type Iib including antibodies and ELISA kits against LDLR, CFH, FH, APOB, APOLIPOPROTEIN B.

Hyperlipoproteinemia Type Iib Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hyperlipoproteinemia Type Iib below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1841 products for the study of Hyperlipoproteinemia Type Iib that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

LDLR Antibody (C7)
NBP1-78159
Western Blot: LDL R Antibody (C7) [NBP1-78159] - Total protein from human HeLa and HepG2 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 0.5 ug/mL anti-LDL receptor in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: LDL R Antibody (C7) [NBP1-78159] - Image from a customer review on porcine intestinal epithelial cells IPEC-J2.

Mouse Monoclonal
Species Human, Rat, Porcine
Applications WB, EM, ELISA

     1 Review

20 Publications
Complement Factor H Antibody [Unconjugated]
AF4779
Complement Factor H was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human Complement Factor H Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4779) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=

Goat Polyclonal
Species Human
Applications WB, IHC

     2 Reviews

Fumarase Antibody
NBP1-31336
Western Blot: Fumarase Antibody [NBP1-31336] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Fumarate hydratase antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Fumarase Antibody [NBP1-31336] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Fumarate hydratase protein stained by Fumarate hydratase antibody diluted at 1:500.Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
Apolipoprotein B/ApoB Antibody
NB200-527
Western Blot: Apolipoprotein B/ApoB Antibody [NB200-527] - Alcohol feeding significantly down-regulated ApoB expression in mouse liver. Image from verified customer review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IP

     2 Reviews

5 Publications
Lipoprotein a Antibody (4H1)
NBP2-37477
Western Blot: Lipoprotein a Antibody (4H1) [NBP2-37477] - Western blot analysis using LPA mAb against human LPA recombinant protein. (Expected MW is 34.1 kDa)Immunocytochemistry/Immunofluorescence: Lipoprotein a Antibody (4H1) [NBP2-37477] - Immunofluorescence analysis of HepG2 cells using LPA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

2 Publications
Apolipoprotein A-I/ApoA1 Antibody
NB600-609

Goat Polyclonal
Species Human, Mouse
Applications WB, ELISA, ICC/IF

9 Publications
Proprotein Convertase 9/PCSK9 [HRP]
DPC900
Proprotein Convertase 9/PCSK9 [HRP] Proprotein Convertase 9/PCSK9 [HRP]


Species Human

     1 Review

22 Publications
Apolipoprotein E/ApoE Antibody (WUE-4)
NB110-60531
Immunohistochemistry-Paraffin: Apolipoprotein E/ApoE Antibody (WUE-4) [NB110-60531] - ApoE was detected in immersion fixed paraffin-embedded sections of human liver using anti-human mouse monoclonal antibody (Catalog # NB110-60531) at 1:200 dilution overnight at 4C. Tissue was stained using the VisuCyte anti-mouse HRP polymer detection reagent (Catalog # VC001) with DAB chromogen (brown) and counterstained with hematoxylin (blue). Images may not be copied, printed or otherwise disseminated without express written permission of Novus Biologicals a bio-techne brand.Western Blot: Apolipoprotein E/ApoE Antibody (WUE-4) [NB110-60531] - ApoE Antibody (WUE-4) [NB110-60531] - Detection of ApoE in human tissue lysate using NB110-60531. Lane 1: liver Lane 2: brain

Mouse Monoclonal
Species Human, Mouse, Rat (Negative)
Applications WB, ELISA, Flow

     2 Reviews

23 Publications
Soluble Liver/Pancreas Antigen Antibody
NBP2-20454
Western Blot: Soluble Liver/Pancreas Antigen Antibody [NBP2-20454] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:5000.Immunohistochemistry-Paraffin: Soluble Liver/Pancreas Antigen Antibody [NBP2-20454] - Paraffin-embedded colon carcinoma. SLA/LP antibody dilution: 1:500

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

HMG-CoA Reductase/HMGCR Antibody (JF0981)
NBP2-66888
Western Blot: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888] - Analysis of HMGCR on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (ET1702-41, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.Positive control: Lane 1: Hela cell lysateLane 2: THP-1 cell lysateSimple Western: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888] - SVG-A whole cell lysate. Antibody at 1:25 dilution. Image from verified customer review.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IP

     1 Review

1 Publication
Thyroglobulin Antibody (2H11 + 6E1)
NBP2-34294
Immunohistochemistry-Paraffin: Thyroglobulin Antibody (2H11 + 6E1) [NBP2-34294] - Thyroglobulin staining in thyroid tissue of normal C57 mouse (Red). Dilution is 1:100. This image was submitted via customer Review.Immunohistochemistry-Paraffin: Thyroglobulin Antibody (2H11 + 6E1) [NBP2-34294] - Analysis using Azide/BSA FREE version of NBP2-34294. Human Thyroid stained with Thyroglobulin Ab (2H11 + 6E1).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications Flow, IHC, IHC-P

     2 Reviews

1 Publication
Transcobalamin II Antibody
AF7895
Western blot shows lysates of HUVEC human umbilical vein endothelial cells and RPMI 8226 human multiple myeloma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human/Mouse/Rat Transcobalamin II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7895) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Transcobalamin II was detected in immersion fixed paraffin-embedded sections of human kidney using Sheep Anti-Human/Mouse/Rat Transcobalamin II Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7895) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB, IHC

CD55/DAF Antibody
NBP1-85466
Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining in human lung and kidney tissues using anti-CD55 antibody. Corresponding CD55 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: CD55/DAF Antibody [NBP1-85466] - Staining of human kidney shows low expression as expected.

Rabbit Polyclonal
Species Human, Mouse, Feline
Applications WB, IHC, IHC-P

2 Publications
Lipoprotein Lipase/LPL Antibody [Unconjugated]
AF7197
Western blot shows lysates of SH‑SY5Y human neuroblastoma cell line and NMuMG mouse mammary gland epithelial cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Lipoprotein Lipase/LPL Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7197) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class= Lipoprotein Lipase/LPL was detected in immersion fixed paraffin-embedded sections of human heart using Goat Anti-Human/Mouse Lipoprotein Lipase/LPL Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7197) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, IHC, ICC

1 Publication
CETP Antibody (ATM192)
NB300-558
Western Blot: CETP Antibody (ATM192) [NB300-558] - Analysis of human liver extract.Immunocytochemistry/Immunofluorescence: CETP Antibody (ATM192) [NB300-558] - Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a CETP monoclonal antibody at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody and nuclei with DAPI (blue) is shown.

Mouse Monoclonal
Species Human, Bovine, Rabbit
Applications WB, ELISA, ICC/IF

1 Publication
Insulin Antibody (E2-E3 (same as INS04))
NBP2-34260
Western Blot: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Probing of Western blots of pancreatic lysates from control and iron overloaded Tg40 PrP and PrP-/- mice with antibodies specific for insulin dimer and pentamer (upper and lower panels) shows decreased expression in Tg40 PrP relative to PrP-/- samples (lanes 1 & 5 vs. 3 & 7). Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-24786-1), licensed under a CC-BY licence.Immunohistochemistry: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Immunohistochemistry of pancreas shows relatively higher reactivity for insulin in PrP-/- relative to Tg40 PrP sections (panels 1 & 3). Iron overloading decreases insulin reactivity in Tg40 PrP but not in PrP-/- samples (panels 1 vs. 2 & 3 vs. 4). Reaction for glucagon is higher in iron overloaded Tg40 PrP relative to control samples (panels 5 & 6). The difference is minimal in PrP-/- samples (panels 7 & 8). Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41598-018-24786-1), licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

     5 Reviews

1 Publication
C-Reactive Protein/CRP [HRP]
DCRP00
C-Reactive Protein/CRP [HRP] C-Reactive Protein/CRP [HRP]


Species Human

     4 Reviews

83 Publications

Related Genes

Hyperlipoproteinemia Type Iib has been researched against:

Related Pathways

Hyperlipoproteinemia Type Iib has been linked to:

Related Diseases

Hyperlipoproteinemia Type Iib has been studied in relation to diseases such as:

Related PTMs

Hyperlipoproteinemia Type Iib has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hyperlipoproteinemia Type Iib is also known as Familial Combined Hyperlipoproteinemia, Familial Defective Apolipoprotein B-100, Hyperlipoproteinemia Type Ii, Hyperlipoproteinemia, Familial Combined, Type Iib Hyperlipoproteinaemia.