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Hyper Ldl Cholesterolemia: Disease Bioinformatics

Hypercholesterolemia (also known as high cholesterol) occurs when abnormally high levels of certain types of cholesterol are in the blood (>5.2 mmol/L). This increase of cholesterol can cause plaque buildup in the artery walls, inevitably causing damage to organs and tissues when blood flow is restricted. Borderline hypercholesterolemia is defined when levels are between 200-239 mg/dL. Hypercholesterolemia is significantly correlated with increased incidence and risk of atherosclerosis, heart attack, and stroke. Risk is increased with smoking, diabetes, high blood pressure, obesity, and poor exercise in combination with a poor diet. Nonfamilial hypercholesterolemia is the most common form as it is present in people with a susceptible genotype that is aggravated by excessive amounts of saturated fats and cholesterol. Familial hypercholesterolemia is a genetic disorder that is inherited, making prevalence within a family approximately 50%. LDL (low-density lipoprotein) cholesterol, commonly referred to as the "bad" cholesterol, tends to clog arteries with time. LDL effects can be counteracted with HDL (high-density lipoprotein) cholesterol. Treatments focus on reducing the risk of cardiovascular disease by decreasing blood cholesterol levels. Medications may be diagnosed to help with this process.

Hyper Ldl Cholesterolemia Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hyper Ldl Cholesterolemia below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 216 products for the study of Hyper Ldl Cholesterolemia that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Western blot shows lysates of human thyroid tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Thyroglobulin Monoclonal Antibody (Catalog # MAB8306) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Thyroglobulin was detected in immersion fixed paraffin-embedded sections of human thyroid cancer tissue using Mouse Anti-Human Thyroglobulin Monoclonal Antibody (Catalog # MAB8306) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Species Human
Applications WB, IHC

Related Genes

Hyper Ldl Cholesterolemia has been researched against:

Related Pathways

Related Diseases

Hyper Ldl Cholesterolemia has been studied in relation to diseases such as:

Related PTMs

Alternate Names

Hyper Ldl Cholesterolemia is also known as Hyper Ldl Cholesterolaemia.