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Hyper Hdl Cholesterolaemia: Disease Bioinformatics

Hypercholesterolemia (also known as high cholesterol) occurs when abnormally high levels of certain types of cholesterol are in the blood (>5.2 mmol/L). This increase of cholesterol can cause plaque buildup in the artery walls, inevitably causing damage to organs and tissues when blood flow is restricted. Borderline hypercholesterolemia is defined when levels are between 200-239 mg/dL. Hypercholesterolemia is significantly correlated with increased incidence and risk of atherosclerosis, heart attack, and stroke. Risk is increased with smoking, diabetes, high blood pressure, obesity, and poor exercise in combination with a poor diet. Nonfamilial hypercholesterolemia is the most common form as it is present in people with a susceptible genotype that is aggravated by excessive amounts of saturated fats and cholesterol. Familial hypercholesterolemia is a genetic disorder that is inherited, making prevalence within a family approximately 50%. HDL (high-density lipoprotein) is a type of cholesterol, commonly known as "good" cholesterol, that fights artery-clogging LDL (low density lipoprotein) cholesterol by flushing LDL into the liver for disposal. Eating unsaturated fat will increase HDL levels. Treatments focus on reducing the risk of cardiovascular disease by decreasing blood cholesterol levels. Medications may be diagnosed to help with this process.

Hyper Hdl Cholesterolaemia Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hyper Hdl Cholesterolaemia below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 72 products for the study of Hyper Hdl Cholesterolaemia that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Western Blot: ApoE Antibody (WUE-4) [NB110-60531] - 50 ug protein per lane for liver lysate and 0.5 ul of plasma at 9% SDS. Samples are loaded onto the gel as the following order: human liver lysate, mouse liver lysate, rat liver lysate, human plasma, and mouse plasma. Image from confirmed customer review.Flow Cytometry: ApoE Antibody (WUE-4) [NB110-60531] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using ApoE antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used.

Mouse Monoclonal
Species Human, Mouse, Rat (Negative)
Applications WB, ELISA, Flow

     2 Reviews

9 Publications

Related Genes

Hyper Hdl Cholesterolaemia has been researched against:

Related Pathways

Related PTMs

Alternate Names

Hyper Hdl Cholesterolaemia is also known as Hyper Hdl Cholesterolemia.