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Hereditary Spherocytosis: Disease Bioinformatics

Research of Hereditary Spherocytosis has been linked to Anemia, Anemia, Hemolytic, Hemolysis (disorder), Anemia, Hemolytic, Congenital, Thalassemia. The study of Hereditary Spherocytosis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hereditary Spherocytosis include Pathogenesis, Transport, Localization, Anion Transport, Aging. These pathways complement our catalog of research reagents for the study of Hereditary Spherocytosis including antibodies and ELISA kits against SPHEROCYTOSIS, MAP3K14, RBC, SLC4A1, ANK1.

Hereditary Spherocytosis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hereditary Spherocytosis below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1390 products for the study of Hereditary Spherocytosis that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-23603
Western Blot: NIK/MAP3K14 Antibody [NBP2-23603] - Detection of MAP3K14 in U2OS cell lysate.Immunocytochemistry/Immunofluorescence: NIK/MAP3K14 Antibody [NBP2-23603] - MAP3K14 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NB120-11012
Western Blot: Band 3 Antibody (BIII 136) [NB120-11012] - Human erythrocytes ghosts extract was separated on SDS-PAGE and probed with Monoclonal Anti-Band 3 Clone: BIII-136. The antibody was developed using Goat Anti-Mouse IgG-Peroxidase and AEC substrate.

Mouse Monoclonal
Species Human, Bovine (Negative), Canine (Negative)
Applications WB, ELISA, ICC/IF

NBP1-71805
Western Blot: Ankyrin 1 Antibody [NBP1-71805] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.  Affinity purified rabbit anti-Ankyrin 1 antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  Ankyrin 1 was also immunoprecipitated by another rabbit anti-Ankyrin 1 antibody, which recognizes an upstream epitope.

Rabbit Polyclonal
Species Human
Applications WB, IP

     1 Review

2 Publications
H00002035-M01
Western Blot: EPB41 Antibody (3D9) [H00002035-M01] - Analysis of EPB41 expression in transfected 293T cell line by EPB41 monoclonal antibody (M01), clone 3D9.Lane 1: EPB41 transfected lysate(81 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: EPB41 Antibody (3D9) [H00002035-M01] - Analysis of monoclonal antibody to EPB41 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

NB100-236
Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Immunoblot analyses of protein expression for Nrf2 and antioxidant enzymes. Representative immunoblots of cytosolic extracts from the hearts of young and old mice under basal conditions and following EES. Protein blots were probed with anti-HO1, NQO1, GCLM, GCLC, Catalase, SOD1, SOD2, GSR, G6PD, GPX1 and GAPDH. Individual lanes indicate a single animal. Densitometry analysis of respective protein signals was performed using Image-J and expressed as relative intensity units calculated as mean values of young and old, *p<0.05. Individual lanes indicate each animal (n?=?6). #p<0.05-between basal and EES.  Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0045697), licensed under a CC-BY licence.Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Detection of Human and Mouse G6PD by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-G6PD antibody NB100-236 used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IB, IHC

17 Publications
MEP00B
 Erythropoietin/EPO [HRP] Erythropoietin/EPO [HRP]


Species Mouse

77 Publications
NBP2-79772
Western Blot: Spectrin alpha 1 Antibody (SPTA1/1832) [NBP2-79772] - Western Blot Analysis of Human K562 cell lysate using Spectrin alpha 1 Antibody (SPTA1/1832).Immunohistochemistry-Paraffin: Spectrin alpha 1 Antibody (SPTA1/1832) [NBP2-79772] - Formalin-fixed, paraffin-embedded human Tonsil stained with Spectrin alpha 1 Antibody (SPTA1/1832).

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

NBP2-31572
Western Blot: EPB41L1 Antibody [NBP2-31572] - Analysis using Anti-EPB41L1 antibody NBP2-31572 (A) shows similar pattern to independent antibody NBP2-31650 (B).Immunocytochemistry/Immunofluorescence: EPB41L1 Antibody [NBP2-31572] - Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-66881
Western Blot: Haptoglobin Antibody (JM10-79) [NBP2-66881] - Analysis of Haptoglobin on different cells lysates using anti-Haptoglobin antibody at 1/500 dilution. Positive control: Lane 1: Hela Lane 2: HepG2Immunocytochemistry/Immunofluorescence: Haptoglobin Antibody (JM10-79) [NBP2-66881] - Staining Haptoglobin in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

H00002038-M01
Western Blot: EPB42 Antibody (2G12) [H00002038-M01] - Analysis of EPB42 expression in transfected 293T cell line by EPB42 monoclonal antibody (M01), clone 2G12.Lane 1: EPB42 transfected lysate(69.5 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: EPB42 Antibody (2G12) [H00002038-M01] - Analysis of monoclonal antibody to EPB42 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

NB100-1519
Western Blot: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Staining of HepG2 (A) and Daudi cell lysates with antibody at 1 ug/mL (B) and HeLa (C) and Jurkat (D) cell lysates with antibody at 0.3 ug/mL (35 ug protein in RIPA buffer). Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (4 ug/mL), showing cytoplasmic and nuclear/Vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (4 ug/mL).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

1 Publication
2914-HT


Species Human

15 Publications
NB300-574
Western Blot: Spectrin beta 1 Antibody (4C3) [NB300-574] - Analysis of 25 ug of Hela cell lysates.Immunocytochemistry/Immunofluorescence: Spectrin beta 1 Antibody (4C3) [NB300-574] - Analysis of Spectrin beta-1 (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without primary antibody (left).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

1 Publication
NBP2-16382
Western Blot: ETFA Antibody [NBP2-16382] - Wild-type (WT) and ETFA knockout (KO) 293T cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with ETFA antibody diluted at 1:1000. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: ETFA Antibody [NBP2-16382] - Confocal immunofluorescence analysis of methanol-fixed HeLa, using ETFA antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NB120-22711
Immunocytochemistry/Immunofluorescence: MUC-1 Antibody (SM3) [NB120-22711] - MCF7 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.05% Triton-X100. The cells were incubated with anti-MUC1 [SM3] at 5 ug/ml overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.Immunohistochemistry-Paraffin: MUC-1 Antibody (SM3) [NB120-22711] - IHC analysis of formalin fixed paraffin embedded tissue section of human breast cancer xenograft using MUC-1 antibody clone SM3 at 1:10 dilution. The xenograft section depicted a very specific and intense signal in the periphery of the cancer cells. The necrotic cells also developed a strong immune-positivity while the tumor stroma as well as the nuclei of cells were negative for immunostaining.

Mouse Monoclonal
Species Human, Mouse
Applications ELISA, Flow, ICC/IF

11 Publications

Related Genes

Hereditary Spherocytosis has been researched against:

Related PTMs

Hereditary Spherocytosis has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hereditary Spherocytosis is also known as hereditary spherocytosis, congenital spherocytic hemolytic anemia, hereditary spherocytosis (disorder), minkowski chauffard syndrome, spherocytosis hereditary, spherocytosis, type 1, anemia spherocytic, hartnup disease, spherocytosis, h disease, anemia, hs.