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Hereditary Motor Neurone Disease: Disease Bioinformatics

Research of Hereditary Motor Neurone Disease has been linked to Motor Neuron Disease, Atrophy, Muscular Atrophy, Amyotrophic Lateral Sclerosis, Sclerosis. The study of Hereditary Motor Neurone Disease has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hereditary Motor Neurone Disease include Pathogenesis, Transport, Aging, Cell Proliferation, Proteolysis. These pathways complement our catalog of research reagents for the study of Hereditary Motor Neurone Disease including antibodies and ELISA kits against MOTOR NEURON DEGENERATION, AKR1B1, AR, AREG, BDNF.

Hereditary Motor Neurone Disease Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hereditary Motor Neurone Disease below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 837 products for the study of Hereditary Motor Neurone Disease that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-56603
Western Blot: Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) [NB100-56603] - Analysis using Azide Free version of NB100-56603. LNCaP cells (passage number 38) were serum-starved for 2 days. After serum starvation, cells were (A) left untreated, (B) treated with 100 ng/ml IGF-1 for 4h, or (C) incubated with 20 um LY294002 for 30 mi

Mouse Monoclonal
Species Human, Primate
Applications WB, IHC, IHC-P

12 Publications
NBP2-24915
Western Blot: SOD1/Cu-Zn SOD Antibody [NBP2-24915] -  Analysis of SOD in liver lysate of 1) human, 2) mouse and 3) rat using this antibody. 025 ug/ml.Immunohistochemistry-Paraffin: SOD1/Cu-Zn SOD Antibody [NBP2-24915] -  Analysis of Superoxide Dismutase 1 in paraffin-embedded formalin-fixed human liver tissue using an isotype control (top) and NBP2-24915 (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC-P

     1 Review

3 Publications
NBP2-16468
Western Blot: Ferredoxin Reductase Antibody [NBP2-16468] - Sample (30 ug of whole cell lysate) A: A549 B: HCT116 10% SDS PAGE gel, diluted at 1:1000.Immunohistochemistry-Paraffin: Ferredoxin Reductase Antibody [NBP2-16468] - Ferredoxin Reductase antibody detects Ferredoxin Reductase protein at mitochondria in rat adrenal gland by immunohistochemical analysis. Sample: Paraffin-embedded rat adrenal gland. Ferredoxin Reductase antibody diluted at 1:500.

Rabbit Polyclonal
Species Human, Rat
Applications WB, IHC, IHC-P

NBP1-89146
Western Blot: AKR1B1 Antibody [NBP1-89146] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: AKR1B1 Antibody [NBP1-89146] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

AF1436
Western blot shows lysates of mouse spleen tissue, mouse liver tissue, and mouse bone marrow. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse ALS Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1436) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB

     1 Review

1 Publication
H00006607-M01
Western Blot: SMN2 Antibody (2B11-2A9) [H00006607-M01] - SMN2 monoclonal antibody (M01), clone 2B11-2A9 Analysis of SMN2 expression in IMR-32.Immunocytochemistry/Immunofluorescence: SMN2 Antibody (2B11-2A9) [H00006607-M01] - Analysis of monoclonal antibody to SMN2 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

NBP1-31237
Western Blot: VAP-A Antibody [NBP1-31237] - Sample (30 ug of whole cell lysate) A:H1299 12% SDS PAGE, antibody diluted at 1:1000.Immunohistochemistry-Paraffin: VAP-A Antibody [NBP1-31237] - Paraffin-embedded breast ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

3 Publications
NBP2-34068
Western Blot: hnRNP-Q Antibody [NBP2-34068] - Analysis in human cell line Daudi.Immunohistochemistry-Paraffin: hnRNP-Q Antibody [NBP2-34068] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal and glial cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB100-1936
Western Blot: SMN Antibody (2B1) [NB100-1936] - Western blot analysis of SMN expression in 1) HeLa, 2) NTera2, 3) HepG2, 4) MCF7, 5) NIH 3T3, 6) PC12 and 7) COS7 whole cell lysates.Immunocytochemistry/Immunofluorescence: SMN Antibody (2B1) [NB100-1936] - The SMN antibody was tested at a 1:250 dilution in HeLa cells against Dylight 488 (Green). Actin nuclei were counterstained against Phalloidin 568 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

19 Publications
NBP1-89676
Western Blot: hnRNP-R Antibody [NBP1-89676] - Analysis in human cell line HEK 293.Immunocytochemistry/Immunofluorescence: hnRNP-R Antibody [NBP1-89676] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP2-20439
Western Blot: SNRPN Antibody [NBP2-20439] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 12% SDS PAGE gel, diluted at 1:500.Western Blot: SNRPN Antibody [NBP2-20439] - Sample (30 ug of whole cell lysate) A: JurKat 12% SDS PAGE gel, diluted at 1:1000.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

248-BD/CF
1 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human BDNF (Catalog #<br>248‑BD/CF) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2-2 ng/mL.


Species Human, Mouse, Rat

77 Publications
H00023435-M01
Western Blot: TDP-43/TARDBP Antibody (2E2-D3) [H00023435-M01] - TARDBP monoclonal antibody (M01), clone 2E2-D3 Analysis of TARDBP expression in A-431.Immunocytochemistry/Immunofluorescence: TDP-43/TARDBP Antibody (2E2-D3) [H00023435-M01] - Analysis of monoclonal antibody to TARDBP on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     2 Reviews

143 Publications
NB300-135
Western Blot: 200kDa Neurofilament Heavy Antibody [NB300-135] - Western blot analysis of 200kDa Neurofilament Heavy expression in rat spinal cord extract.  The first lane is Coomassie Brilliant Blue stained and the second lane is probed with rabbit anti-Neurofilament Heavy antibody NB300-135.  The NF-H corresponds to a weight of 200kDa.Immunocytochemistry/Immunofluorescence: 200kDa Neurofilament Heavy Antibody [NB300-135] - rat spinal cord stained with Neurofilament Heavy [NF-H] antibody NB300-135 (green) and UCHL1 antibody NB110-58869 (red).  NB300-135 binds primarily to phosphorylated axonal forms of NF-H, and so stains axons coursing between the large UCHL1 positive neurons. These large cells are alpha motorneurons and UCHL1 is a major component of the perikarya and dendrites of these cells.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

8 Publications
NBP2-00935
Western Blot: OSBP1 Antibody (1F2) [NBP2-00935] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OSBP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OSBP1.Immunocytochemistry/Immunofluorescence: OSBP1 Antibody (1F2) [NBP2-00935] Staining of COS7 cells transiently transfected by pCMV6-ENTRY OSBP1.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NBP1-76798
Western Blot: Stathmin 1 Antibody [NBP1-76798] - EL4 cell lysate with op18 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.Immunocytochemistry/Immunofluorescence: Stathmin 1 Antibody [NBP1-76798] - Stathmin 1 antibody was tested in PC12 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

NBP1-59632
Western Blot: EAAT2/GLT1 Antibody [NBP1-59632] - Fetal Brain Lane A: Primary Antibody  Lane B:Primary Antibody + Blocking Peptide  Primary Antibody Concentration:1ug/ml  Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/Lane Gel Concentration: 0.12Immunohistochemistry-Paraffin: EAAT2/GLT1 Antibody [NBP1-59632] - Human alveolar cell.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NBP1-42827
Western Blot: MAP1B [p Thr1265] Antibody (SuperBUGS) [NBP1-42827] - Analysis of phosphorylated MAP1B in chick embryos (lane 1) and rat neonatal brain (lane 2).Immunohistochemistry: MAP1B [p Thr1265] Antibody (SuperBUGS) [NBP1-42827] - Immunohistochemical analysis of rat spinal cord transverse section from an E12 embryo.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

8 Publications

Related Genes

Hereditary Motor Neurone Disease has been researched against:

Related PTMs

Hereditary Motor Neurone Disease has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hereditary Motor Neurone Disease is also known as Familial Motor Neuron Disease, Hereditary Motor Neuron Disease.