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Hereditary Corneal Dystrophy: Disease Bioinformatics

Research of Hereditary Corneal Dystrophy has been linked to Dystrophy, Corneal Diseases, Age Related Macular Degeneration, Familial Amyloid Polyneuropathy, Type V, Edema. The study of Hereditary Corneal Dystrophy has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hereditary Corneal Dystrophy include Pathogenesis, Localization, Wound Healing, Secretion, Aging. These pathways complement our catalog of research reagents for the study of Hereditary Corneal Dystrophy including antibodies and ELISA kits against TGFBI, TACSTD2, ABCA4, CHST6, HAZE.

Hereditary Corneal Dystrophy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hereditary Corneal Dystrophy below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 725 products for the study of Hereditary Corneal Dystrophy that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP1-88606
Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP1-88606] - Staining of human skin shows moderate positivity in extracellular matrix of dermis.Immunohistochemistry-Paraffin: Beta Ig-h3/TGFBI Antibody [NBP1-88606] - Immunohistochemistry analysis in human gallbladder and pancreas tissues. Corresponding RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human
Applications Simple Western, IHC, IHC-P

3 Publications
AF650
Western blot shows lysates of NCI‑N87 human gastric carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human TROP‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF650) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=TROP‑2 was detected in immersion fixed paraffin-embedded sections of human brain (frontal cortex) using Goat Anti-Human TROP‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF650) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Flow, IHC

     1 Review

16 Publications
NBP1-30032
Western Blot: ABCA4 Antibody (3F4) [NBP1-30032] - Characterization of ABCA4 mRNA expression and western blot analyses of ABCA4 protein levels in the canine retina. Western blot analyses of ABCA4 (above), GAPDH (middle), and RHO (below) protein levels in retinal tissue of dogs with the three different genotypes. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pgen.1007873), licensed under a CC-BY licence.Immunohistochemistry-Frozen: ABCA4 Antibody (3F4) [NBP1-30032] - IHC-Fr of normal feline retina with antibodies ABCA4 3F4 (red) and HCAR (green). ABCA4 antibody (1:1000) labels outer segments of photoreceptors and HCAR antibody labels cones. IHC-Fr image submitted by a verified customer review.

Mouse Monoclonal
Species Human, Mouse, Bovine
Applications WB, ICC/IF, IHC

     1 Review

5 Publications
NBP2-67627
Western Blot: PYK2/FAK2 Antibody (SC06-15) [NBP2-67627] - Analysis of PYK2 on mouse brain lysates using anti-PYK2 antibody at 1:1000 dilution.Immunocytochemistry/Immunofluorescence: PYK2/FAK2 Antibody (SC06-15) [NBP2-67627] - Staining PYK2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X-100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

NBP2-93402
Western Blot: UBIAD1 Antibody [NBP2-93402] - Analysis of extracts of various cell lines, using UBIAD1. Exposure time: 60s.Immunocytochemistry/Immunofluorescence: UBIAD1 Antibody [NBP2-93402] - Analysis of U2OS cells using UBIAD1 at dilution of 1:100. Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-79718
Immunohistochemistry-Paraffin: Cytokeratin 3 Antibody (KRT3/2130) [NBP2-79718] - Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin 3 Antibody (KRT3/2130).Immunohistochemistry-Paraffin: Cytokeratin 3 Antibody (KRT3/2130) [NBP2-79718] - Formalin-fixed, paraffin-embedded human Ovary stained with Cytokeratin 3 Antibody (KRT3/2130).

Mouse Monoclonal
Species Human
Applications IHC, IHC-P, PA

NBP1-33177
Western Blot: Gelsolin/GSN Antibody [NBP1-33177] - Non-transfected (-) and transfected (+) HeLa whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Gelsolin antibody [C2C3], C-term.Immunocytochemistry/Immunofluorescence: Gelsolin/GSN Antibody [NBP1-33177] -  Methanol-fixed HeLa, using Gelsolin antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with Red at 1:2000.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
NB300-164
Dual RNAscope ISH-IHC: Bestrophin 1 Antibody (E6-6) [NB300-164] - Formalin-fixed paraffin-embedded tissue sections of human duodenum were probed for Bestrophin 1 mRNA (ACD RNAScope Probe, catalog # 433181; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse anti-human  (Novus Biologicals catalog # NB300-164) at 0.3ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue).  IHC signal is confined to cytoplasm.Immunohistochemistry-Paraffin: Bestrophin 1 Antibody (E6-6) [NB300-164] - Bestrophin 1 was detected in immersion fixed paraffin sections of human small intestine using t Mouse Anti-Human Bestrophin 1 Monoclonal Antibody (Catalog # NB300-164) at 5 ug/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cell surface and extracellular.

Mouse Monoclonal
Species Human, Porcine, Canine
Applications WB, ICC/IF, IHC

     1 Review

40 Publications
NBP3-10377
Western Blot: VSX1 Antibody [NBP3-10377] - Western blot analysis using NBP3-10377 on Human Liver  as a positive control. Antibody Titration: 0.2-1 ug/ml

Rabbit Polyclonal
Species Human
Applications WB

NBP1-32797
Western Blot: MLYCD Antibody [NBP1-32797] - A. 30 ug C8D30 whole cell lysate/extract 7.5% SDS-PAGE MCD antibody dilution: 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: MLYCD Antibody [NBP1-32797] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MCD stained by MCD antibody [N2C1], Internal  diluted at 1:2000. Blue: Hoechst 33342 staining.Scale bar= 10 um.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

NBP1-46156
Western Blot: SLC4A11 Antibody [NBP1-46156] - Porcine kidney tissue lysates. Lane 1 - 15 ug. Lane 2 - 30 ug. Lane 3 - 60 ug. Antibody at 1:500. Secondary antibody at 1:1000. Western blot image submitted by a verified customer review.Immunohistochemistry-Paraffin: SLC4A11 Antibody [NBP1-46156] - Staining of paraffin embedded Human Kidney. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

     1 Review

1 Publication
NBP1-05987
Immunohistochemistry: ZEB1 Antibody [NBP1-05987] - Immunohistochemical staining results of EMT regulators in HG-PanIN: SNAIL, SLUG, TWIST1, and ZEB1. We categorized and defined three grades: grade 0, <10% positive staining; grade 1, 10%-50% positive; grade 2, 50%< positive Image collected and cropped by CiteAb from the following publication (https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.2016) licensed under a CC-BY licence.Western Blot: ZEB1 Antibody [NBP1-05987] - Samples: Whole cell lysate (15 ug) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ZEB1 antibody (NBP1-05987) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, GS

     6 Reviews

65 Publications
NBP1-85361
Western Blot: CYP4V2 Antibody [NBP1-85361] - Analysis in human cell line SK-MEL-30 and human cell line HeLa.Immunohistochemistry-Paraffin: CYP4V2 Antibody [NBP1-85361] - Staining of human skeletal muscle shows very weak positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-13857
Immunohistochemistry-Paraffin: COL8A2 Antibody [NBP2-13857] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in glomeruli.Immunohistochemistry-Paraffin: COL8A2 Antibody [NBP2-13857] Staining of human placenta shows positivity in a subset of lymphoid cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-56853
Western Blot: RPE Antibody [NBP1-56853] - Human Muscle lysate, concentration 0.2-1 ug/ml.Immunocytochemistry/Immunofluorescence: RPE Antibody [NBP1-56853] - Antibody  0 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver  Observed Staining: Cytoplasm but only in connective tissue cells in the interlobular septum, very low tissue distribution Primary Antibody

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-68268
Western Blot: CDC2L5 Antibody [NB100-68268] - Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-CDC2L5 antibody NB100-68268 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate.  CDC2L5 was also immunoprecipitated by rabbit anti-CDC2L5 antibody that  recognizes a downstream epitope.    Detection: Chemiluminescence with an exposure time of 3 minutes (A) and 10 seconds (B).

Rabbit Polyclonal
Species Human
Applications WB, IP

1 Publication
H00065057-M02
Western Blot: ACD Antibody (1D8-1B6) [H00065057-M02] - Western Blot analysis of ACD expression in IMR-32 ( Cat # L008V1 ).Immunocytochemistry/Immunofluorescence: ACD Antibody (1D8-1B6) [H00065057-M02] - Analysis of monoclonal antibody to ACD on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ChIP, ELISA

     1 Review

8 Publications
NBP2-60655
Western Blot: ERG Antibody [NBP2-60655] - Total protein from Human THP-1, Jurkat and K562 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-ERG in blocking buffer and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: ERG Antibody [NBP2-60655] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-ERG at 5 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC


Related Genes

Hereditary Corneal Dystrophy has been researched against:

Related PTMs

Hereditary Corneal Dystrophy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hereditary Corneal Dystrophy is also known as Hereditary Corneal Dystrophies.