Home » Diseases » Hereditary Autoinflammatory Diseases: Disease Bioinformatics
Submit your image related to Diseases to be featured!
Submit an Image

Get Social

Submit your Twitter account related to Hereditary Autoinflammatory Diseases to be featured!
Submit an Account

Blogs

 Submit your blog on Hereditary Autoinflammatory Diseases to be featured!
Submit a Blog

Events

 Submit your event on Hereditary Autoinflammatory Diseases to be featured!
Submit an Event

Videos

Submit your video on Hereditary Autoinflammatory Diseases to be featured!
Submit a Video

Charities

Submit your charity on Hereditary Autoinflammatory Diseases to be featured!
Submit a Charity

Hereditary Autoinflammatory Diseases: Disease Bioinformatics

Research of Hereditary Autoinflammatory Diseases has been linked to Familial Mediterranean Fever, Inflammation, Brucellosis, Tnf Receptor-associated Periodic Fever Syndrome (t, Cryopyrin-associated Periodic Syndromes. The study of Hereditary Autoinflammatory Diseases has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hereditary Autoinflammatory Diseases include Pathogenesis, Inflammatory Response, Secretion, Immune Response, Cytokine Production. These pathways complement our catalog of research reagents for the study of Hereditary Autoinflammatory Diseases including antibodies and ELISA kits against MEFV, TNF, FAMILIAL MEDITERRANEAN FEVER, NLRP3, TNFRSF1A.

Hereditary Autoinflammatory Diseases Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Hereditary Autoinflammatory Diseases below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2177 products for the study of Hereditary Autoinflammatory Diseases that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NOD2 Antibody (2D9) - BSA Free
NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY licence.Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

24 Publications
MEFV Antibody
NB600-809
Immunocytochemistry/Immunofluorescence: MEFV Antibody [NB600-809] - Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).Flow Cytometry: MEFV Antibody [NB600-809] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Goat Polyclonal
Species Human
Applications Flow, ICC/IF, PEP-ELISA

1 Publication
Caspase-1 Antibody (14F468) - BSA Free
NB100-56565
Simple Western: Caspase-1 Antibody (14F468) [NB100-56565] - Simple Western lane view shows a specific band for Caspase 1 in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.Immunohistochemistry: Caspase-1 Antibody (14F468) [NB100-56565] - Activity of Casp1 in OHT-injured and normotensive control eyes. (A) Casp1 was detected by intraocular injection FLICA660-labeled substrate (green) in vivo 24 h after injury. Bright labeling (arrows) is evident in cells in the GCL and inner nuclear layer (INL) layers of the OHT-challenged retinas, a diffuse labeling of cell processes located in the IPL. Casp1 activity is diminished in Panx1-/- (Px1-/- OHT) retinas and WT retinas treated with probenecid (WT/Pbcd) at 12 h postinjury. Image collected and cropped by CiteAb from the following publication (https://www.frontiersin.org/article/10.3389/fnmol.2019.00036/full), licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

63 Publications
GDI1 Antibody
NBP1-31528
Western Blot: GDI1 Antibody [NBP1-31528] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.Immunohistochemistry-Paraffin: GDI1 Antibody [NBP1-31528] - Sample: Paraffin-embedded mouse lung. GDI1 antibody dilution: 1:500.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

NALP12 Antibody - BSA Free
NBP1-76293
Western Blot: NALP12 Antibody [NBP1-76293] - B6 mice (n = 6) were infected ocularly with 2.5 x 105 pfu/eye of HSV-1 laboratory strains McKrae, 17, F, RE or KOS or with clinical isolates KOS79 and KOS63 (mock-infected mice (n = 6) used as controls). 48 hrs later, animals were euthanized & corneas were excised & homogenized in lysis buffer, and WB was performed for NLRP3, NLRP6, NLRP12, IFI16/p204, & AIM2 (beta-actin used as a control). Three WB performed using different corneal lysates harvested from three sets of corneas from 2 mice (4 corneas/lysate). Graphs (mean plus SD) show fold change in expression of NLRP3, NLRP6, NLRP12, IFI16/p204, and AIM2 at 48 hrs post-infection compared to controls, and normalized to beta-actin. Representative densitometric analysis is shown compared to control. Image collected and cropped by CiteAb from the following publication (https://www.frontiersin.org/articles/10.3389/fimmu.2019.01631/full), licensed under a CC-BY licence.Immunocytochemistry/Immunofluorescence: NALP12 Antibody [NBP1-76293] - Immunofluorescence of NALP12 in human brain tissue with NALP12 antibody at 20 ug/mL.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

1 Publication
ASC/TMS1 Antibody - BSA Free
NBP1-78977
Simple Western: ASC/TMS1 Antibody [NBP1-78977] - Lane view shows a specific band for ASC TMS1 in 0.5 mg/ml of MCF-7 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.Immunocytochemistry/Immunofluorescence: ASC/TMS1 Antibody [NBP1-78977] - NLRP3 activation was evaluated by visualizing the co-localization of NLRP3 and apoptosis-associated speck-like protein (ASC) using immunocytochemistry (A). PLoS One. 2020 Jun 17;15(6):e0234039. doi: 10.1371/journal.pone.0234039. (Catalog # NBP1-78977AF647)

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     2 Reviews

34 Publications
PSTPIP1 Antibody
NBP1-85764
Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP1-85764] - Staining in human bone marrow and cerebral cortex tissues using anti-PSTPIP1 antibody. Corresponding PSTPIP1 RNA-seq data are presented for the same tissues.Western Blot: PSTPIP1 Antibody [NBP1-85764] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Calcyphosine Antibody
NBP1-91746
Immunohistochemistry-Paraffin: Calcyphosine Antibody [NBP1-91746] - Staining in human fallopian tube and colon tissues using anti-CAPS antibody. Corresponding CAPS RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: Calcyphosine Antibody [NBP1-91746] - Staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

2 Publications
NLRP3/NALP3 Antibody - BSA Free
NBP2-12446
Western Blot: NLRP3/NALP3 Antibody [NBP2-12446] - C-AR inhibited NLRP3 inflammasome activation in synovial tissue. NLRP3 protein expression in succinate-stimulated synovial fibroblasts. The results were derived from four independent experiments for immunohistochemistry staining and Western blot and expressed as the mean +/- SD. *p < 0.05 vs. the model; #p < 0.05 vs. the indicated treatment. Image collected and cropped by CiteAb from the following publication (http://journal.frontiersin.org/article/10.3389/fimmu.2016.00532/full), licensed under a CC-BY licence.Immunohistochemistry-Paraffin: NLRP3/NALP3 Antibody [NBP2-12446] - Analysis of human esophagus using NLRP3/NALP3 antibody at 1:50 on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0) and endogenous peroxidase quenching with peroxide block. The sections were incubated with primary antibody for 30 minutes and Bond Polymer Refine Detection (Leica Biosystems) with DAB was used for signal development followed by counterstaining with hematoxylin. Whole slide scanning and capturing of representative images was performed using Aperio AT2 (Leica Biosystems). Cytoplasmic staining in the squamous epithelium was observed. Staining was performed by Histowiz.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     4 Reviews

166 Publications
CADPS Antibody
NBP2-38871
Immunocytochemistry/Immunofluorescence: CADPS Antibody [NBP2-38871] - Staining of human cell line SK-MEL-30 shows localization to vesicles.Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human kidney shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

IL-1ra/IL-1F3/IL1RN [HRP]
DRA00B
IL-1ra/IL-1F3/IL1RN [HRP] IL-1ra/IL-1F3/IL1RN [HRP]


Species Human
Applications ELISA

90 Publications
TNF RI/TNFRSF1A [HRP]
DRT100
TNF RI/TNFRSF1A [HRP] TNF RI/TNFRSF1A [HRP]


Species Human
Applications ELISA

81 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

749 Publications
IL-1 beta/IL-1F2 [Unconjugated]
201-LB/CF
Recombinant Human IL-1 beta /IL-1F2 (Catalog # 201-LB/CF) stimulates cell proliferation of the D10.G4.1 mouse helper T cell line. The ED<SUB>50</SUB> for this effect is <12 pg/mL.1 μg/lane of Recombinant Human IL-1 beta /IL-1F2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.


Species Human
Applications BA

533 Publications
MVK Antibody [Unconjugated]
AF8516
MVK was detected in immersion fixed A431 human epithelial carcinoma cell line using Rabbit Anti-Human MVK Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8516) at 2 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (red; Catalog # <a class=Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, A431 human epithelial carcinoma cell line, and HEK001 human epidermal keratinocyte cell line. PVDF membrane was probed with 0.1 µg/mL of Rabbit Anti-Human MVK Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8516) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, IP

IL-18/IL-1F4 [HRP]
DL180
IL-18/IL-1F4 [HRP] IL-18/IL-1F4 [HRP]


Species Human
Applications ELISA

18 Publications
TEF1 Antibody
NBP2-94035
Western Blot: TEF1 Antibody [NBP2-94035] - Analysis of extracts of various cell lines, using TEAD1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit. Exposure time: 1s.Immunocytochemistry/Immunofluorescence: TEF1 Antibody [NBP2-94035] - Analysis of MCF7 cells using TEF1 .

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF


Related Genes

Hereditary Autoinflammatory Diseases has been researched against:

Related Pathways

Hereditary Autoinflammatory Diseases has been linked to:

Related Diseases

Hereditary Autoinflammatory Diseases has been studied in relation to diseases such as:

Related PTMs

Hereditary Autoinflammatory Diseases has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hereditary Autoinflammatory Diseases is also known as Disease, Hereditary Autoinflammatory, Diseases, Hereditary Autoinflammatory, Hereditary Autoinflammatory Disease, Hereditary Periodic Fever, Hereditary Periodic Fever Syndromes.