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Haff Syndrome: Disease Bioinformatics

Haff disease is a syndrome of unexplained rhabdomyolysis following consumption of certain types of fish; it is caused by an unidentified toxin. Rhabdomyolysis is a clinical syndrome caused by injury to skeletal muscle that results in release of muscle cell contents into the circulation. In 1997, six cases of Haff disease were identified in the United States (four in California and two in Missouri) among persons who ate buffalo fish a bottom-feeding species found mostly in the Mississippi River. Rhabdomyolysis is a condition in which skeletal muscle is broken down, releasing muscle enzymes and electrolytes from inside the muscle cells. Risks of rhabdomyolysis include muscle breakdown and kidney failure because the cellular component myo-globin is toxic to the kidneys. Rhabdomyolysis is relatively uncommon, but it most often occurs as the result of extensive muscle damage as, for example, in crush injury or electrical shock. Drugs or toxins may also cause this disorder.

Haff Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Haff Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 17 products for the study of Haff Syndrome that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Western Blot: CPT2 Antibody [NBP1-85471] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)<br/>Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunocytochemistry/Immunofluorescence: CPT2 Antibody [NBP1-85471] - Staining of human cell line A-431 shows positivity in nucleoli, nucleus but not nucleoli & mitochondria.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

Related Genes

Haff Syndrome has been researched against:

Related Pathways

Related PTMs

Alternate Names

Haff Syndrome is also known as Toxic Myoglobinuria.