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Fibrodysplasia Ossificans Progressiva: Disease Bioinformatics

Research of Fibrodysplasia Ossificans Progressiva has been linked to Myositis Ossificans, Myositis, Heterotopic Ossification, Hereditary Diseases, Congenital Abnormality. The study of Fibrodysplasia Ossificans Progressiva has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Fibrodysplasia Ossificans Progressiva include Ossification, Pathogenesis, Endochondral Ossification, Bmp Signaling Pathway, Regeneration. These pathways complement our catalog of research reagents for the study of Fibrodysplasia Ossificans Progressiva including antibodies and ELISA kits against IA, ACTIVIN A, ACVR1, BMP2, BMP4.

Fibrodysplasia Ossificans Progressiva Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Fibrodysplasia Ossificans Progressiva below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 778 products for the study of Fibrodysplasia Ossificans Progressiva that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

NBP1-33500
Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33500] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Activin A Receptor type I antibody diluted at 1:500.Immunohistochemistry-Frozen: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP1-33500] - Frozen sectioned adult mouse retina. Green: Activin A Receptor type I protein stained by Activin A Receptor type I antibody diluted at 1:250. Red: Protein kinase C alpha staining. Blue: Fluoroshield with DAPI.

Rabbit Polyclonal
Species Mouse, Rat
Applications WB, IHC, IHC-Fr

     1 Review

314-BP
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

     3 Reviews

240 Publications
NBP1-88085
Western Blot: CHTOP Antibody [NBP1-88085] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: CHTOP Antibody [NBP1-88085] - Staining of human cell line A-431 shows localization to nuclear speckles & cytoplasmic bodies.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

H00011116-M01
Western Blot: FGFR1OP Antibody (2B1) [H00011116-M01] - Analysis of FGFR1OP expression in transfected 293T cell line by FGFR1OP monoclonal antibody (M01), clone 2B1.Lane 1: FGFR1OP transfected lysate(43.1 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: FGFR1OP Antibody (2B1) [H00011116-M01] - Analysis of monoclonal antibody to FGFR1OP on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

2 Publications
6057-NG
BG01V human embryonic stem cells were cultured in Mouse Embryonic Fibroblast Conditioned Media supplemented with FGF basic (5 ng/mL). Stem cells were driven into early cells of the neuroectoderm using a 3 day incubation in recombinant human Noggin (25 µg/mL) from either R&D Systems (Lot 1, Lot 2; Catalog #<br>6057-NG) or from two separate competitors (Competitor 1, Competitor 2). Control cells were not incubated in Noggin (No Noggin). The cells were stained for the early ectoderm marker, Otx2, and the neuroectoderm marker, SOX1. (A) Representative images of SOX1 (green), Otx2 (red), and DAPI (blue) staining in embryonic stem cells differentiated with Noggin from R&D Systems or Noggin from Competitor 2. (B) SOX1+ clusters were quantified under each of the indicated culture conditions. Cells treated with R&D Systems Noggin showed an increase in SOX1+ cells compared to both untreated and competitor-treated cells. R&D Systems Noggin showed consistent differentiation across the lots tested. BG01V human embryonic stem cells are licensed from ViaCyte, Inc.


Species Human

     4 Reviews

55 Publications
355-BM


Species Human, Mouse, Rat

     6 Reviews

101 Publications
NBP2-45808
Immunohistochemistry: GARS Antibody (4G4) [NBP2-45808] - Analysis of Carcinoma of Human prostate tissue (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)Immunohistochemistry: GARS Antibody (4G4) [NBP2-45808] - Analysis of Human colon tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Mouse monoclonal
Species Human
Applications IHC

NB100-56656
Western Blot: SMAD1/5/8/9 Antibody [NB100-56656] - Analysis using SMAD antibody. Lysate from Saos-2 cells probed with SMAD antibody at 1:1000.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

1 Publication
NBP1-31730
Western Blot: G protein alpha Antibody [NBP1-31730] - A. 30 ug NIH-3T3 whole cell lysate/extract B. 30 ug JC whole cell lysate/extract 12 % SDS-PAGE G protein alpha Antibody dilution: 1:1000Immunohistochemistry-Paraffin: G protein alpha Antibody [NBP1-31730] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

MAB3777
Western blot shows lysates of Neuro-2A mouse neuroblastoma cell line, Jurkat human acute T cell leukemia cell line, and MCF-7 human breast cancer cell line. PVDF membrane was probed with 1 µg/mL Rat Anti-Human/Mouse/Rat FKBP12 Monoclonal Antibody (Catalog # MAB3777) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # <a class=

Rat Monoclonal
Species Human, Mouse, Rat
Applications WB

     1 Review

1 Publication
NB100-1533
Western Blot: POMC Antibody [NB100-1533] - Western blot analysis of POMC using NB100-1533 at 0.01ug/ml in NIH 3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Analysis in human Anterior Pituitary Gland shows vesilulate staining in glandular cells.

Goat Polyclonal
Species Human, Mouse, Porcine
Applications WB, ICC/IF, IHC

6 Publications
NBP2-45897
Western Blot: GLYAT Antibody (4D1) [NBP2-45897] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GLYAT.Immunohistochemistry: GLYAT Antibody (4D1) [NBP2-45897] - Analysis of Carcinoma of Human liver tissue.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min)

Mouse Monoclonal
Species Human
Applications WB, IHC

AF2250
Smad5 was detected in immersion fixed paraffin-embedded sections of human colon using 5 µg/mL Human Smad5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2250) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit  (brown; Catalog # <A class=

Goat Polyclonal
Species Human
Applications WB, IHC

1 Publication
NBP1-32108
Western Blot: CRAT Antibody [NBP1-32108] - Rat tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CAT1 antibody  diluted at 1:500.Immunocytochemistry/Immunofluorescence: CRAT Antibody [NBP1-32108] - Methanol-fixed H1299, using CRAT (NBP1-32108) antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF

MAB2006
RUNX2/CBFA1 was detected in immersion fixed U2OS human osteosarcoma cell line using Rat Anti-Human RUNX2/CBFA1 Monoclonal Antibody (Catalog # MAB2006) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red, upper panel; Catalog # <A class=NoLineLink href=

Rat Monoclonal
Species Human
Applications ICC

     1 Review

12 Publications
NBP2-24916
Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     1 Review

4 Publications
NBP2-24716
Western Blot: MTSS1 Antibody [NBP2-24716] - Analysis of MTSS1 in human testis lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse and 4) rat testis lysate using NBP2-24716 at 2 ug/ml, 4 ug/ml and 2 ug/ml, respectively.Immunohistochemistry-Paraffin: MTSS1 Antibody [NBP2-24716] - Analysis of human colon using this antibody at 10 ug/ml.

Rabbit Polyclonal
Species Human, Primate
Applications WB, IHC-P

NB110-41404
Western Blot: Glutamine Synthetase Antibody [NB110-41404] - Analysis of glutamine synthase. 40ug of lysates from mouse (Lanes M), rat (Lanes R), pig (Lanes P), bovine (Lanes B), or human (Lanes Hu) retina were probed. A 42 kDa band was identified in lysates from retinas of all species.Immunohistochemistry: Glutamine Synthetase Antibody [NB110-41404] - Localization of glutamine synthase in the retina. Paraffin sections of mouse (A, B), rat (C, D, G-I), or human (E, F) retina fixed in 4% paraformaldehyde were reacted with anti-glutamine synthase (red fluorescence staining in B, D, G, I, and brown immuno-peroxidase reaction [using ABC kit and visualization with DAB product in F]. Nuclei in some immunofluorescence experiments (A-D) were stained with DAPI (shown in cyan), and with nuclear fast red in E and F.  On inspection at low magnification, anti- glutamine synthase reacted with a single population of cells extending from the ganglion cell layer (GCL) through the inner nuclear layer (INL). No signal was detected in controls either pre-incubated with 100ug/ml of the immunizing peptide (A) or with pre-immune serum (C, E). The pattern of staining observed in all experiments is typicals. This finding was confirmed by co-localization (indicated by yellow in I) of glutamine synthase (red in G) with antoher marker of glutamine synthase (green in H).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC

     1 Review

1 Publication

Related Genes

Fibrodysplasia Ossificans Progressiva has been researched against:

Related PTMs

Fibrodysplasia Ossificans Progressiva has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Fibrodysplasia Ossificans Progressiva is also known as fibrodysplasia ossificans progressiva, progressive myositis ossificans, myositis ossificans progressiva, multiple endocrine neoplasia (men) syndrome, stone man syndrome, fop.