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Familial Hemophagocytic Lymphocytosis: Disease Bioinformatics

Research of Familial Hemophagocytic Lymphocytosis has been linked to Lymphohistiocytosis, Hemophagocytic, Histiocytosis, Non-langerhans-cell, Lymphatic Diseases, Histiocytosis Haematophagic, Pancytopenia. The study of Familial Hemophagocytic Lymphocytosis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Familial Hemophagocytic Lymphocytosis include Pathogenesis, Macrophage Activation, Exocytosis, Secretion, Coagulation. These pathways complement our catalog of research reagents for the study of Familial Hemophagocytic Lymphocytosis including antibodies and ELISA kits against UNC13D, STX11, PRF1, ZNF395, STXBP2.

Familial Hemophagocytic Lymphocytosis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Familial Hemophagocytic Lymphocytosis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2709 products for the study of Familial Hemophagocytic Lymphocytosis that can be applied to Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Zinc finger protein 395 Antibody
NBP3-17459
Western Blot: Zinc finger protein 395 Antibody [NBP3-17459] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10; Lane 2: RT4; Lane 3: U-251 MG; Lane 4: Human Plasma; Lane 5: Liver; Lane 6: TonsilImmunocytochemistry/Immunofluorescence: Zinc finger protein 395 Antibody [NBP3-17459] - Staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NOD2 Antibody (2D9) - BSA Free
NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY licence.Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

24 Publications
UNC13D/Munc 13-4 Antibody
NB100-41385
Western Blot: UNC13D/Munc 13-4 Antibody [NB100-41385] - RBL-2H3 from Wt or shRNA Munc13-4 lentiviral stable expression whole cell lysate. 50 ug total protein. WB image submitted by a verified customer review.Immunohistochemistry-Paraffin: UNC13D/Munc 13-4 Antibody [NB100-41385] - Staining of paraffin embedded Mouse Lung with antibody at 0.5 ug/mL (wt in A and KO in B).

Goat Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

6 Publications
Rab27a Antibody (1G7)
H00005873-M02
Western Blot: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of RAB27A expression in transfected 293T cell line by RAB27A monoclonal antibody (M02), clone 1G7.Lane 1: RAB27A transfected lysate(24.9 KDa).Lane 2: Non-transfected lysate.Immunohistochemistry-Paraffin: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of monoclonal antibody to RAB27A on formalin-fixed paraffin-embedded human lymphoma. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ELISA, Flow

12 Publications
FHL5 Antibody
NBP1-32660
Western Blot: FHL5 Antibody [NBP1-32660] - Sample (30 ug of whole cell lysate) A: 293T B: Raji 12 % SDS PAGE, antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: FHL5 Antibody [NBP1-32660] - Paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
SH2D1A Antibody (1C9)
H00004068-M01
Western Blot: SH2D1A Antibody (1C9) [H00004068-M01] - Analysis of SH2D1A expression in transfected 293T cell line by SH2D1A monoclonal antibody (M01), clone 1C9.Lane 1: SH2D1A transfected lysate(14.2 KDa).Lane 2: Non-transfected lysate.Flow Cytometry: SH2D1A Antibody (1C9) [H00004068-M01] - Intracellular staining of human T cells with SH2D1A monoclonal antibody or isotype control antibody, followed by a Polyclonal Goat Anti-Mouse/RPE secondary antibody. Grey filled histogram: Isotype control, empty blue histogram: SH2D1A antibody. Flow cytometry image submitted by a verified customer review.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

     1 Review

7 Publications
CD8 Antibody (53-6.7) - BSA Free
NBP1-49045
Flow Cytometry: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of lymph nodes by multiple staining.Immunohistochemistry-Paraffin: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - CD8 alpha expression in mouse spleen tissue using anti-CD8 alpha antibody. Image from verified customer review.

Rat Monoclonal
Species Mouse, Rat
Applications Flow, ICC/IF, IHC

     3 Reviews

22 Publications
FHL2 Antibody
NBP1-84978
Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84978] - Analysis in human heart muscle and liver tissues. Corresponding FHL2 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84978] - Staining of human cerebellum, heart muscle, liver and skeletal muscle using Anti-FHL2 antibody NBP1-84978 (A) shows similar protein distribution across tissues to independent antibody NBP1-84979 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
STX11 Antibody
NBP1-86122
Western Blot: STX11 Antibody [NBP1-86122] - Analysis in human cell line HDLM-2.Immunohistochemistry-Paraffin: STX11 Antibody [NBP1-86122] - Staining of human lymph node shows strong cytoplasmic positivity in reaction center cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
Perforin Antibody (CB5.4) - BSA Free
NBP1-97512
Western Blot: Perforin Antibody (CB5.4) [NBP1-97512] - Detection of perforin in the mouse T cell clone B6.1. (lane 1). Absence of perforin in the mouse fibroblast cell line NIH.3T3 (lane 2). The protein migrates as a 66 kDa species. Method: Cell extracts from the T cell clone B6.1 (2x10^6) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and probed with the CB5.4 antibody at 1 ug/ml. Proteins were visualized using a peroxidase-conjugated antibody to rat IgG and a chemiluminescence detection system.

Rat Monoclonal
Species Mouse
Applications WB, ICC/IF, IHC

6 Publications
Syntaxin-BP2 Antibody
AF5900
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Goat Polyclonal
Species Human
Applications WB

XIAP Antibody [Unconjugated]
AF8221
<P align=left>XIAP was detected in immersion fixed paraffin-embedded sections of human lymphoma using 5 µg/mL Goat Anti-Human/Mouse/Rat XIAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8221) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=XIAP was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using 15 µg/mL Goat Anti-Human/Mouse/Rat XIAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8221) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

16 Publications
IL-6 [HRP]
D6050
IL-6 [HRP] IL-6 [HRP]


Species Human
Applications ELISA

718 Publications
IL-2 [Unconjugated]
202-IL
Recombinant Human IL-2 (Catalog # 202-IL) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<sub>50</sub> for this effect is 0.0500-0.250 ng/mL.As an alternative, please consider our next generation Recombinant Human IL-2 (<a class=


Species Human
Applications BA

     4 Reviews

352 Publications
GM-CSF [Unconjugated]
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
LAMC2 Antibody (CL2980)
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
LAMP-1/CD107a Antibody (5E7) - BSA Free
NBP2-52721
Immunocytochemistry/Immunofluorescence: LAMP-1/CD107a Antibody (5E7) [NBP2-52721] - ICC usage of NBP2-52721. Image submittied via verified customer review.Immunohistochemistry-Paraffin: LAMP-1/CD107a Antibody (5E7) [NBP2-52721] - Analysis of FFPE human kidney tissue section using LAMP-1 antibody (clone 5E7) at 1:100 dilution. The antibody generated a specific cytoplasmic staining (with dotted appearance) in all the ductal and tubular epithelial cells.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

     2 Reviews

4 Publications
HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
NBP2-79843
Western Blot: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Western Blot Analysis of Ramos cell lysate using HLA DQ/DR/DP Antibody (HLA-Pan/2967R).Immunocytochemistry/Immunofluorescence: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Immunofluorescence staining of PFA-fixed Ramos cells. HLA DQ/DR/DP Recombinant Rabbit Monoclonal Antibody (HLA DQ/DR/DP/2967R) followed by goat anti-rabbit IgG-CF488 (green). Nuclei stained with RedDot.

Rabbit Monoclonal
Species Human
Applications WB, ELISA, Flow

FHL3 Antibody
NBP3-04622
Western Blot: FHL3 Antibody [NBP3-04622] - Analysis of extracts of various cell lines, using FHL3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic KitImmunocytochemistry/Immunofluorescence: FHL3 Antibody [NBP3-04622] - Immunofluorescence analysis of HeLa cells using FHL3 Rabbit pAb (NBP3-04622) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF


Related Genes

Familial Hemophagocytic Lymphocytosis has been researched against:

Related Pathways

Familial Hemophagocytic Lymphocytosis has been linked to:

Related Diseases

Familial Hemophagocytic Lymphocytosis has been studied in relation to diseases such as:

Related PTMs

Familial Hemophagocytic Lymphocytosis has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Familial Hemophagocytic Lymphocytosis is also known as Familial Erythrophagocytic Lymphohistiocytosis, Familial Haemophagocytic Histiocytosis, Familial Haemophagocytic Lymphohistiocytosis, Familial Haemophagocytic Reticulosis, Familial Hemophagocytic Histiocytosis.