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Familial Hemophagocytic Lymphocytosis: Disease Bioinformatics

Research of Familial Hemophagocytic Lymphocytosis has been linked to Lymphohistiocytosis, Hemophagocytic, Histiocytosis, Non-langerhans-cell, Lymphatic Diseases, Histiocytosis Haematophagic, Pancytopenia. The study of Familial Hemophagocytic Lymphocytosis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Familial Hemophagocytic Lymphocytosis include Pathogenesis, Macrophage Activation, Exocytosis, Secretion, Coagulation. These pathways complement our catalog of research reagents for the study of Familial Hemophagocytic Lymphocytosis including antibodies and ELISA kits against UNC13D, STX11, PRF1, ZNF395, STXBP2.

Familial Hemophagocytic Lymphocytosis Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Familial Hemophagocytic Lymphocytosis below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2066 products for the study of Familial Hemophagocytic Lymphocytosis that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NB100-41385
Western Blot: UNC13D/Munc 13-4 Antibody [NB100-41385] - RBL-2H3 from Wt or shRNA Munc13-4 lentiviral stable expression whole cell lysate. 50 ug total protein. WB image submitted by a verified customer review.Immunohistochemistry-Paraffin: UNC13D/Munc 13-4 Antibody [NB100-41385] - Staining of paraffin embedded Mouse Lung with antibody at 0.5 ug/mL (wt in A and KO in B).

Goat Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

5 Publications
NBP1-86122
Western Blot: STX11 Antibody [NBP1-86122] - Analysis in human cell line HDLM-2.Immunohistochemistry-Paraffin: STX11 Antibody [NBP1-86122] - Staining of human lymph node shows strong cytoplasmic positivity in reaction center cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
NBP1-97512
Western Blot: Perforin Antibody (CB5.4) [NBP1-97512] - Detection of perforin in the mouse T cell clone B6.1. (lane 1). Absence of perforin in the mouse fibroblast cell line NIH.3T3 (lane 2). The protein migrates as a 66 kDa species.  Method: Cell extracts from the T cell clone B6.1 (2x10^6) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and probed with the CB5.4 antibody at 1 ug/ml. Proteins were visualized using a peroxidase-conjugated antibody to rat IgG and a chemiluminescence detection system.

Rat Monoclonal
Species Mouse
Applications WB, ICC/IF, IHC

6 Publications
NBP3-10503
Western Blot: Zinc finger protein 395 Antibody [NBP3-10503] - Western blot analysis using NBP3-10503 on Human PANC1 as a positive control. Antibody Titration: 0.2-1 ug/ml

Rabbit Polyclonal
Species Human
Applications WB

AF5900
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Goat Polyclonal
Species Human
Applications WB

NBP1-91899
Western Blot: FHL3 Antibody [NBP1-91899] - Analysis in control (vector only transfected HEK293T lysate) and FHL3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: FHL3 Antibody [NBP1-91899] - Staining of human cell line A-431 shows localization to nucleus. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-84978
Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84978] - Analysis in human heart muscle and liver tissues. Corresponding FHL2 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: FHL2 Antibody [NBP1-84978] - Staining of human cerebellum, heart muscle, liver and skeletal muscle using Anti-FHL2 antibody NBP1-84978 (A) shows similar protein distribution across tissues to independent antibody NBP1-84979 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
H00004068-M01
Western Blot: SH2D1A Antibody (1C9) [H00004068-M01] - Analysis of SH2D1A expression in transfected 293T cell line by SH2D1A monoclonal antibody (M01), clone 1C9.Lane 1: SH2D1A transfected lysate(14.2 KDa).Lane 2: Non-transfected lysate.Flow Cytometry: SH2D1A Antibody (1C9) [H00004068-M01] - Intracellular staining of human T cells with SH2D1A monoclonal antibody or isotype control antibody, followed by a Polyclonal Goat Anti-Mouse/RPE secondary antibody. Grey filled histogram: Isotype control, empty blue histogram: SH2D1A antibody. Flow cytometry image submitted by a verified customer review.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ELISA, Flow

     1 Review

7 Publications
202-IL
1 μg/lane of Recombinant Human IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human IL-2 (Catalog # 202-IL) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<SUB>50</SUB> for this effect is 0.05-0.25 ng/mL.


Species Human

     23 Reviews

315 Publications
H00005873-M02
Western Blot: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of RAB27A expression in transfected 293T cell line by RAB27A monoclonal antibody (M02), clone 1G7.Lane 1: RAB27A transfected lysate(24.9 KDa).Lane 2: Non-transfected lysate.Immunohistochemistry-Paraffin: Rab27a Antibody (1G7) [H00005873-M02] - Analysis of monoclonal antibody to RAB27A on formalin-fixed paraffin-embedded human lymphoma. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human, Mouse, Rabbit
Applications WB, ELISA, Flow

12 Publications
NBP1-32660
Western Blot: FHL5 Antibody [NBP1-32660] - Sample (30 ug of whole cell lysate)A: 293TB: Raji12 % SDS PAGE, antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: FHL5 Antibody [NBP1-32660] - Paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
NBP1-49045
Flow Cytometry: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of lymph nodes by multiple staining.Immunohistochemistry-Paraffin: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - CD8 alpha expression in mouse spleen tissue using anti-CD8 alpha antibody. Image from verified customer review.

Rat Monoclonal
Species Mouse, Rat
Applications Flow, ICC/IF, IHC

     3 Reviews

16 Publications
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
7954-GM/CF


Species Human

1 Publication
NBP2-45041
Flow Cytometry: HLA DQ Antibody (SPV-L3) [NBP2-45041] - Flow Cytometric Analysis of Raji cells. HLA DQ Antibody (SPV-L3) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).

Mouse Monoclonal
Species Human, Porcine
Applications Flow, ICC/IF, IF

1 Publication
NB120-19294
Western Blot: LAMP-1/CD107a Antibody [NB120-19294] - Analysis of 20 ug of HeLa cell lysate and 5 ul of Molecular Weight Protein Ladder per well.Immunocytochemistry/Immunofluorescence: LAMP-1/CD107a Antibody [NB120-19294] - Cathepsin D (CathD) expression and localization in primary neurons. Colocalization of transfected CathD with LAMP-1/CD107a. CathD transfected neurons were examined by co-immunostaining of LAMP-1/CD107a and CathD. Yellow colored cytoplasmic spots are indicative of co-localization of transfected cathepsins and LAMP-1/CD107a. Scale bar = 10 micron. Image collected and cropped by CiteAb from the following publication (http://molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-6-37), licensed under a CC-BY licence.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     2 Reviews

26 Publications
NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY licence.Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

23 Publications
D6050
 IL-6 [HRP] IL-6 [HRP]


Species Human

     26 Reviews

487 Publications
NB100-56183
Western Blot: XIAP Antibody - Unpurified [NB100-56183] - Analysis of XIAP in various tumor cell lines using this antibody at 1:2000.Immunocytochemistry/Immunofluorescence: XIAP Antibody [NB100-56183] - Immunocytochemistry for XIAP expression levels in IMR32 cells (Scale bar: 67 um). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41598-018-20499-7/figures/7) licensed under a CC-BY licence.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     2 Reviews

5 Publications

Related Genes

Familial Hemophagocytic Lymphocytosis has been researched against:

Related PTMs

Familial Hemophagocytic Lymphocytosis has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Familial Hemophagocytic Lymphocytosis is also known as Familial Erythrophagocytic Lymphohistiocytosis, Familial Haemophagocytic Histiocytosis, Familial Haemophagocytic Lymphohistiocytosis, Familial Haemophagocytic Reticulosis, Familial Hemophagocytic Histiocytosis.