Autoimmune Myasthenia Gravis (MG) is a autoimmune neuromuscular disease that causes defective neuromuscular transmission of electrical impulses, weakening muscles. Myasthenia Gravis is a chronic disorder where the connection between the nerve and the muscle is interrupted. Facial muscles such as eye and eyelids, facial expression and swallowing are commonly affected by the disorder. Medications, immunosuppressives, and occasional tymectomies are effective therapies for autoimmune myasthenia gravis. Autoimmune Myasthenia Gravis can be caused experimentally through the injection of purified neuromuscular junction acetylcholine receptors (AChR) and is frequently used to study MG. The process of inducing Myasthenia Gravis from patients to mice is referred to as passive transfer.
Experimental Autoimmune Myasthenia Gravis, Passive Transfer Bioinformatics Tool
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