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Experimental Autoimmune Myasthenia Gravis, Passive Transfer: Disease Bioinformatics

Autoimmune Myasthenia Gravis (MG) is a autoimmune neuromuscular disease that causes defective neuromuscular transmission of electrical impulses, weakening muscles. Myasthenia Gravis is a chronic disorder where the connection between the nerve and the muscle is interrupted. Facial muscles such as eye and eyelids, facial expression and swallowing are commonly affected by the disorder. Medications, immunosuppressives, and occasional tymectomies are effective therapies for autoimmune myasthenia gravis. Autoimmune Myasthenia Gravis can be caused experimentally through the injection of purified neuromuscular junction acetylcholine receptors (AChR) and is frequently used to study MG. The process of inducing Myasthenia Gravis from patients to mice is referred to as passive transfer.

Experimental Autoimmune Myasthenia Gravis, Passive Transfer Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Experimental Autoimmune Myasthenia Gravis, Passive Transfer below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 441 products for the study of Experimental Autoimmune Myasthenia Gravis, Passive Transfer that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

2150-C5/CF
<P align=left>1 μg/lane of Recombinant Mouse Complement Component C5a was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 9 kDa.</P>Recombinant Mouse Complement Component C5a (Catalog # 2150-C5/CF) induces N-acetyl-beta -D-glucosaminidase release from differentiated U937 human histiocytic lymphoma cells. The ED<SUB>50</SUB> for this effect is 5-20 ng/mL.


Species Mouse

31 Publications
NBP2-93726
Western Blot: MYLIP Antibody [NBP2-93726] - Analysis of extracts of various cell lines, using MYLIP at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.Immunohistochemistry-Paraffin: MYLIP Antibody [NBP2-93726] - Paraffin-embedded human prostate using MYLIP.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP1-85537
Immunocytochemistry/Immunofluorescence: Rapsyn Antibody [NBP1-85537] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.Immunohistochemistry-Paraffin: Rapsyn Antibody [NBP1-85537] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
NB200-540
Flow (Intracellular): Complement C3 Antibody (11H9) [NB200-540] - An intracellular stain was performed on RAW 246.7 cells with Complement C3 (11H9-3-2) antibody NB200-540 (blue) and a matched isotype control NBP2-31382 (orange). Cells were either treated with 3uM Monensin for 3 hours to block the secretion of Complement C3 (B) or grown in normal media (A). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) PE-conjugated secondary antibody (F0102B, R&D Systems).Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern. Fixation in 4% paraformaldehyde in PBS pH 7.4. Vibratome sections of 4 um. Pretreated with 3% hydrogen peroxide for 20 min to quench endogenous peroxidases. Microwaved in antigen unmasking solution for 2-5 minutes as antigen retrieval.

Rat Monoclonal
Species Mouse
Applications Flow, IA, ICC/IF

     2 Reviews

6 Publications
NB120-11899

Rabbit Polyclonal
Species Mouse
Applications WB, IHC, IHC-Fr

NBP2-80406
Western Blot: Complement C7 Antibody (15D1) [NBP2-80406] - Analysis of Complement Complement C7 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (NBP2-80406, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.Positive control: Lane 1: HepG2 cell lysateLane 2: K562 cell lysateLane 3: HUVEC cell lysateImmunocytochemistry/Immunofluorescence: Complement C7 Antibody (15D1) [NBP2-80406] - Staining of C7 in SHG-44 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody (EM1901-14, 1/50) for 1 hour at room temperature, washed with PBS. Alexa Fluor488 Goat anti-Mouse IgG was used as the secondary antibody at 1/1,000 dilution. The nuclear counter stain is DAPI (blue).

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

DIP100
 CXCL10/IP-10/CRG-2 [HRP] CXCL10/IP-10/CRG-2 [HRP]


Species Human

     4 Reviews

102 Publications
H00005688-M01
Western Blot: PSMA7 Antibody (1A10-3G12) [H00005688-M01] - PSMA7 monoclonal antibody (M01), clone 1A10-3G12. Analysis of PSMA7 expression in human omentum, serous carcinoma.Immunocytochemistry/Immunofluorescence: PSMA7 Antibody (1A10-3G12) [H00005688-M01] - Analysis of monoclonal antibody to PSMA7 on HeLa cell. Antibody concentration 1 ~ 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

     1 Review

2 Publications
NBP1-85540
Western Blot: MARCH8 Antibody [NBP1-85540] - Analysis in control (vector only transfected HEK293T lysate) and LY408083 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: MARCH8 Antibody [NBP1-85540] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-85297
Western Blot: MLXIP Antibody [NBP2-85297] - Host: Rabbit. Target Name: MLXIP. Sample Type: Human Adult Placenta. Antibody Dilution: 1.0ug/mlImmunohistochemistry-Paraffin: MLXIP Antibody [NBP2-85297] - Rabbit Anti-MLXIP Antibody. Formalin Fixed Paraffin Embedded Tissue: Human Adult heart. Observed Staining: Cytoplasmic. Primary Antibody Concentration: 1:100. Secondary Antibody: Donkey anti-Rabbit-Cy2/3. Secondary Antibody Concentration: 1:200. Magnification: 20X.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P


Related Genes

Experimental Autoimmune Myasthenia Gravis, Passive Transfer has been researched against:

Related Diseases

Experimental Autoimmune Myasthenia Gravis, Passive Transfer has been studied in relation to diseases such as:

Alternate Names

Experimental Autoimmune Myasthenia Gravis, Passive Transfer is also known as Passive Transfer Experimental Autoimmune Myasthenia Gravis.