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Evans Syndrome: Disease Bioinformatics

Evans Syndrome is an autoimmune disorder that is very rare and causes the individual's immune system to attack its red and white blood cells and platelets. Antibodies are produced to target red blood cells, which is known as Autoimmune Hemolytic anemia, white blood cells, or platelets, which is also known as Idiopathic Thrombocytopenia. It is unclear as to what causes Evans Syndrome, though no genetic links have been made in current research. Steroids are often used as treatment to subdue the defective antibodies and immune system, and chemotherapy can be used in some cases in which the patient does not respond to other treatments, but there is no cure for the disorder. Individuals diagnosed with Evans Syndrome are more likely to develop other autoimmune disorders and malignancies.

Evans Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Evans Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2683 products for the study of Evans Syndrome that can be applied to Western Blot, Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

Western Blot: DAT1 Antibody (mAb16) [NBP2-22164] - Analysis of DAT1 expression in rat striatal membrane tissue lysate.Immunocytochemistry/Immunofluorescence: DAT1 Antibody (mAb16) [NBP2-22164] - The DAT1 antibody was tested in PC12 cells at a 1:250 dilution against DyLight 488 (Green). Actin and nuclei were counterstained with Phalloidin-AlexaFluor 568 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Mouse, Rat, Human (Negative)
Applications WB, ELISA, ICC/IF

     1 Review

11 Publications
Immunohistochemistry: Steroid sulfatase Antibody [NBP1-90095] - Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

3 Publications
Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on  kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern.Immunohistochemistry-Paraffin: Complement C3 Antibody (11H9) [NB200-540] - IHC-P detection of Complement C3 protein in a formalin fixed paraffin embedded tissue section of mouse liver using 1 : 100 dilution of Complement C3 antibody (clone 11H9) NB200-540. Weak but distinct membrane-cytoplasmic immunopositivity was observed in hepatocytes and few cells developed punctate membrane staining.

Rat Monoclonal
Species Mouse
Applications WB, Flow, IA

1 Publication
Immunocytochemistry/Immunofluorescence: Von Willebrand Factor Antibody [NB600-586]Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody [NB600-586] - Staining of formalin-fixed, paraffin-embedded Human Kidney sections with 1:2,000 Rabbit Anti-von Willebrand Factor.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

2 Publications
Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) stimulated to induce Regulatory T Cells (Tregs) with Recombinant Human TGF‑ beta 1 (Catalog # <a class=Mouse splenocytes were stained with Rat Anti-Mouse CD4 APC‑conjugated Monoclonal Antibody (Catalog # <A class=NoLineLink href=

Rabbit Monoclonal
Species Human, Mouse
Applications Flow, IHC, ICC

Western Blot: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Immunoblot of Balb/c thymus (lane 1) and A20 (lane 2) cell lysates with Anti-Mouse CD20 Purified.Flow Cytometry: MS4A1/CD20 Antibody (AISB12) [NBP1-43435] - Staining of BALB/c splenocytes with Anti-Mouse CD19 Alexa Fluor (R) 647 and 1.0 micrograms conjugated anti-Mouse CD20 Purified followed by Anti-Rat IgG PE. Quadrant lines represent Rat IgG2a isotype control staining levels and cells in the lymphocyte gate were used for analysis.

Rat Monoclonal
Species Human, Mouse
Applications WB, Flow

3 Publications
Western Blot: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in the following cell lysates: Lane 1) human spleen 2) human tonsil 3) human placenta 4) human kidney 5) human liver 6) mouse spleen 7) mouse placenta 8) rat placenta.Immunocytochemistry/Immunofluorescence: CD4 Antibody [NBP1-19371] - CD4 antibody was tested in Jurkat cells with Dylight 488 (green). Nuclei were counterstained with DAPI (blue).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     5 Reviews

8 Publications
Western Blot: SH2B2 Antibody [NBP2-13305] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: SH2B2 Antibody [NBP2-13305] - Staining of human cell line MCF7 shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Western Blot: Cytokeratin 20 Antibody (2G3-1C8) [H00054474-M01] - KRT20 monoclonal antibody (M01), clone 2G3-1C8 Analysis of KRT20 expression in A-431.Immunocytochemistry/Immunofluorescence: Cytokeratin 20 Antibody (2G3-1C8) [H00054474-M01] - Analysis of monoclonal antibody to KRT20 on U-2 OS cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

Related Genes

Evans Syndrome has been researched against:

Related PTMs

Evans Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Evans Syndrome is also known as evans' syndrome, other primary thrombocytopenia, primary thrombocytopenia, evan's syndrome, autoimmune hemolytic anemia and autoimmune thrombocytopenia, other primary thrombocytopenia (disorder), primary thrombocytopenia nos (disorder), primary thrombocytopenia (disorder), primary thrombocytopenia nos, thrombocytopenia: primary, evans syndrome (disorder), idiopathic disorder, idopathic purpuric, idiopathic disease, thrombocytopenia, evan syndrome, idiopathic, purpuric.