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Eosinophilia: Disease Bioinformatics

Eosinophilia is a condition in which eosinophils are produced in high levels. Eosinophils are white blood cells that destroy foreign substances and promote inflammation. Eosinophilia has a number of different causes, including toxins, allergies, parasitic or fungal infections, autoimmune diseases, and several types of cancer. The two major types of Eosinophilia are Tissue Eosinophilia, in which the white blood cells are overexpressed in tissue, and Blood Eosinophilia, in which the blood has high levels of Eosinophils. The disease is often discovered when a doctor orders a blood test for a different set of symptoms. The discovery of Eosinophilia in an individual can help lead to an accurate diagnosis. Because Eosinophilia is the result of a different disease, there is no official treatment other than to treat the initial disease.

Eosinophilia Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Eosinophilia below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 4219 products for the study of Eosinophilia that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP2-13967
Western Blot: EPX Antibody [NBP2-13967] - Analysis in human cell line NB4.Immunohistochemistry-Paraffin: EPX Antibody [NBP2-13967] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
7268-CT
Recombinant Human CTLA-4 Fc Chimera (Catalog # 7268-CT) inhibits IL-2 secretion by stimulated Jurkat human acute Tcell leukemia cells. The ED<sub>50</sub> for this effect is 0.03-0.15 μg/mL whenstimulated with 1 μg/mL Recombinant Human B7‑1/CD80 Fc Chimera (Catalog # <a class=


Species Human
Applications BA

     3 Reviews

3 Publications
6507-IL/CF
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 0.05-0.2 ng/mL.


Species Human
Applications BA

3 Publications
MME00
 CCL11/Eotaxin [HRP] CCL11/Eotaxin [HRP]


Species Mouse
Applications ELISA

     1 Review

56 Publications
M5000
 IL-5 [HRP] IL-5 [HRP]


Species Mouse
Applications ELISA

     3 Reviews

83 Publications
D6050
 IL-6 [HRP] IL-6 [HRP]


Species Human
Applications ELISA

     32 Reviews

644 Publications
285-IF
Recombinant Human IFN-gamma  (Catalog # 285‑IF) demonstrates anti-viral activity in HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The activity is over 2-fold greater than the top competitor's IFN-gamma .1 μg/lane of Recombinant Human IFN-gamma  was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.


Species Human
Applications BA

     24 Reviews

400 Publications
210-TA
1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.Recombinant Human TNF-alpha  (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     36 Reviews

719 Publications
203-IL/CF
<P align=left>1 μg/lane of Recombinant Human IL-3 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.<P align=left>Recombinant Human IL-3 (Catalog #<BR>203‑IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<SUB>50</SUB> for this effect is 0.02‑0.1 ng/mL.


Species Human
Applications BA

172 Publications
202-IL
1 μg/lane of Recombinant Human IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.Recombinant Human IL-2 (Catalog # 202-IL) stimulates cell proliferation of the CTLL‑2 mouse cytotoxic T cell line. The ED<SUB>50</SUB> for this effect is 0.05-0.25 ng/mL.


Species Human
Applications BA

     26 Reviews

342 Publications
M1300CB
 IL-13 [HRP] IL-13 [HRP]


Species Mouse
Applications ELISA

     3 Reviews

127 Publications
DY417
 IL-10 [Biotin]


Species Mouse
Applications ELISA

     10 Reviews

256 Publications
7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

1 Publication
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

2 Publications
NBP1-19371
Immunohistochemistry: CD4 Antibody [NBP1-19371] - Increased CD3+ and CD4+ T-cell occurrence in the brainstem of SHR-72 transgenic rat model for tauopathies. (A-D) Immunofluorescence staining showed CD4+ T-cells in SHR-72 transgenic animals. (E- H) Immunofluorescence staining showed more perivascular than brain parenchyma infiltrating CD4+ T-cells in SHR-72 transgenic animals. PLoS One. 2019 May 23;14(5):e0217216. doi: 10.1371/journal.pone.0217216.Immunohistochemistry: CD4 Antibody [NBP1-19371] - DBZ inhibits the accumulation of CD4+ T cells and Th2 differentiation in the AAAs. (B) The representation of immunohistochemical staining for CD4+ in abdominal aorta from four groups (left). Bar graphs show the percentage of CD4+ positive cell areas (right; n=3 per group). Bar: 50 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     9 Reviews

40 Publications
NB500-470
Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Staining of IgE in human peripheral blood with anti-IgE (BE5) PE-CyTM5. Flow Cytometry: IgE Antibody (BE5) [NB500-470] - Surface staining of IgE in human peripheral blood lymphocytes with anti-IgE (BE5) purified, GAM-APC.

Mouse Monoclonal
Species Human
Applications ELISA, Flow

1 Publication
NBP2-76905
Western Blot: RNASE3 Antibody (5G4) [NBP2-76905] - Western blot analysis of Ribonuclease 3 on U937 cell lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used at a 1:500 dilution in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.Lane 1: Anti-Ribonuclease 3 Antibody, (1:500).Lane 2: Anti-Ribonuclease 3 Antibody, (1:500), preincubated with the immunization protein.Immunocytochemistry/Immunofluorescence: RNASE3 Antibody (5G4) [NBP2-76905] - ICC staining Ribonuclease 3 in SHG-44 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with Ribonuclease 3 monoclonal antibody at a dilution of 1:50 for 1 hour at room temperature, washed with PBS. Alexa Fluorc 488 Goat anti-Mouse IgG was used as the secondary antibody at 1/100 dilution. The nuclear counter stain is DAPI (blue).

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

NB100-2289
Knockdown Validated: AHR Antibody [NB100-2289] - Activation of AHR/Nrf2 pathway by PFT-alpha. Knock-down efficiency of AHR siRNA as detected by qPCR (upper part) and western blot (lower part). Relative expression level is shown as fold change normalized to scramble siRNA. All values represent the mean +/- SD of two independent experiments performed in three replicates. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41598-020-58051-1), licensed under a CC-BY licence.Immunohistochemistry: AHR Antibody [NB100-2289] - Staining of Aryl hydrocarbon Receptor in mouse prostate.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

     2 Reviews

7 Publications