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Donohue Syndrome: Disease Bioinformatics

Research of Donohue Syndrome has been linked to Insulin Resistance, Dwarfism, Growth Disorders, Diabetes Mellitus, Growth Retardation. The study of Donohue Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Donohue Syndrome include Transport, Glucose Homeostasis, Pathogenesis, Glucose Transport, Secretion. These pathways complement our catalog of research reagents for the study of Donohue Syndrome including antibodies and ELISA kits against INSR, INS, IGF1, EGF, AURKA.

Donohue Syndrome Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Donohue Syndrome below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2495 products for the study of Donohue Syndrome that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

NBP2-12793
Immunohistochemistry-Paraffin: Insulin Receptor beta Antibody [NBP2-12793] - Staining shows expression of insulin receptor beta in the Cortex in mouse brain. Dilution 1:500Immunoprecipitation: Insulin Receptor beta Antibody [NBP2-12793] - Samples:  Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Insulin Receptor Beta antibody NBP2-12793 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate.  Insulin Receptor Beta was also immunoprecipitated by rabbit anti-Insulin Receptor Beta antibody, which recognizes an upstream epitope.  Detection: Chemiluminescence with exposure times of 30 seconds (A and B).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

2 Publications
NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Insulin E2E3, human pancreas (FFPE), HIER pH 9 antigen retrieval. Image from verified customer review.Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     5 Reviews

1 Publication
291-G1
1 μg/lane of Recombinant Human IGF-I/IGF-1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.Recombinant Human IGF-I/IGF-1 (Catalog # 291-G1) stimulates proliferation in the MCF-7 human breast cancer cell line. The ED<sub>50</sub> for this effect is 0.3‑1.5 ng/mL.


Species Human

     5 Reviews

136 Publications
236-EG
1 µg/lane of Recombinant Human EGF was resolved with SDS-PAGE  and visualized by silver staining under reducing (R) conditions, showing a single band at 6 kDa.Recombinant Human EGF (Catalog # 236‑EG) stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cell line. The ED<sub>50</sub> for this effect is 20‑100 pg/mL.


Species Human

     18 Reviews

447 Publications
NBP1-51843
Simple Western: Aurora A Antibody [NBP1-51843] - Simple Western lane view shows a specific band for Aurora A in 0.5 mg/ml of HeLa lysate.  This experiment was performed under reducing conditions using the 12-230kDa separation system.Immunocytochemistry/Immunofluorescence: Aurora A Antibody [NBP1-51843] - IF Confocal analysis of HeLa cells using Aurora A antibody (NBP1-51843, 1:10). An Alexa Fluor 488-conjugated Goat to rabbit IgG was used as secondary antibody (green). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red). DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

     1 Review

5 Publications
MAB391
 IGF-I R/IGF1R  was detected in perfusion fixed paraffin-embedded sections of mouse heart  using Mouse Anti-Human/Mouse IGF-I R/IGF1R Monoclonal Antibody  (Catalog # MAB391) at 15 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Mouse IgG  VisUCyte™  HRP Polymer  Antibody (Catalog # <a class=<p align=

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, IHC

16 Publications
NB100-82001
Western Blot: IRS1 Antibody [NB100-82001] - Analysis of extracts from 293 cells using IRS-1 (Ab-636) antibodyImmunocytochemistry/Immunofluorescence: IRS1 Antibody [NB100-82001] - Staining of methanol-fixed Hela cells using IRS-1 (Ab-636) antibody

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

3 Publications
AF1067
    Western  blot shows lysates of human, mouse, and rat pituitary gland tissue. PVDF  membrane was probed with 0.5 µg/mL of Goat Anti-Human Growth Hormone  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1067) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Recombinant  Human Growth Hormone protein was serially diluted 2-fold and captured by  Mouse Anti-Human Growth Hormone Monoclonal Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

     3 Reviews

6 Publications
292-G2
1 μg/lane of Recombinant Human IGF‑II/IGF2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.Recombinant Human IGF-II/IGF2 (Catalog # 292‑G2) stimulates cell proliferation in the MCF-7 human breast cancer cell line. The ED<sub>50</sub> for this effect is 1.5‑6 ng/mL.


Species Human

     1 Review

35 Publications
MAB1249
Glucagon was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using 10 µg/mL Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <A class=     beta TC‑6  mouse beta cell insulinoma cell line was stained with Mouse Anti-Human/Mouse  Glucagon Monoclonal Antibody (Catalog # MAB1249, filled histogram) or isotype  control antibody (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse
Applications CyTOF-ready, ICC, ICFlow

     3 Reviews

4 Publications
3 Publications
DGB300
 IGFBP-3 [HRP] IGFBP-3 [HRP]


Species Human

     3 Reviews

32 Publications
AF1280
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and MDA‑MB‑231 human breast cancer cell line. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Mouse EGFR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1280) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=EGFR was detected in immersion fixed frozen sections of mouse embryo (13 d.p.c.) using Goat Anti-Mouse EGFR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1280) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, Simple Western, IHC

     1 Review

7 Publications
NBP1-80670
Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining in human thyroid gland and cerebral cortex tissues using anti-TPO antibody. Corresponding TPO RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Thyroid Peroxidase Antibody [NBP1-80670] - Staining of human cerebral cortex shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

2 Publications
MOB00
 Leptin/OB [HRP] Leptin/OB [HRP]


Species Mouse, Rat

     4 Reviews

120 Publications
NBP1-89679
Western Blot: HNF-4 alpha/NR2A1 Antibody [NBP1-89679] - Analysis in human cell lines Caco-2 and PC-3 using anti-HNF4A antibody. Corresponding HNF4A RNA-seq data are presented for the same cell lines. Loading control: anti-GAPDH.Immunocytochemistry/Immunofluorescence: HNF-4 alpha/NR2A1 Antibody [NBP1-89679] - Staining of human cell line CACO-2 shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

4 Publications