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Disorder Of The Optic Nerve: Disease Bioinformatics

Research of Disorder Of The Optic Nerve has been linked to Glaucoma, Optic Neuropathy, Ischemic, Intraocular Pressure Disorder, Visual Impairment, Blind Vision. The study of Disorder Of The Optic Nerve has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Disorder Of The Optic Nerve include Pathogenesis, Cell Death, Neuroprotection, Transport, Enucleation. These pathways complement our catalog of research reagents for the study of Disorder Of The Optic Nerve including antibodies and ELISA kits against STRABISMUS, APCS, CSF2, CUX1, ERG.

Disorder Of The Optic Nerve Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Disorder Of The Optic Nerve below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1129 products for the study of Disorder Of The Optic Nerve that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-47365
Western Blot: MT-ND4 Antibody [NBP2-47365] - Analysis in human cell line HeLa.Immunohistochemistry-Paraffin: MT-ND4 Antibody [NBP2-47365] - Staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-60655
Western Blot: ERG Antibody [NBP2-60655] - Total protein from Human THP-1, Jurkat and K562 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-ERG in blocking buffer and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: ERG Antibody [NBP2-60655] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-ERG at 5 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBL1-12154
Western Blot: hERG Overexpression Lysate (Adult Normal) [NBL1-12154] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for hERG.


Species Human

AF2558
Western blot shows lysates of mouse kidney tissue, mouse liver tissue, and human kidney tissue. PVDF membrane was probed with 0.2 µg/mL of Sheep Anti-Human/Mouse Pentraxin 2/SAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2558) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=Simple Western lane view shows lysates of mouse kidney tissue, loaded at 0.2 mg/mL. A specific band was detected for Pentraxin 2/SAP at approximately 36 kDa (as indicated) using 2 µg/mL of Sheep Anti-Human/Mouse Pentraxin 2/SAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2558) followed by 1:50 dilution of HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human, Mouse
Applications WB, Simple Western

2 Publications
H00004068-M01
Western Blot: SH2D1A Antibody (1C9) [H00004068-M01] - SH2D1A monoclonal antibody (M01), clone 1C9 Analysis of SH2D1A expression in Jurkat.Western Blot: SH2D1A Antibody (1C9) [H00004068-M01] - Analysis of SH2D1A expression in transfected 293T cell line by SH2D1A monoclonal antibody (M01), clone 1C9.Lane 1: SH2D1A transfected lysate(14.2 KDa).Lane 2: Non-transfected lysate.

Mouse Monoclonal
Species Human
Applications WB, ELISA

6 Publications
H00004535-Q01
12.5% SDS-PAGE Stained with Coomassie Blue.


Species Human

AF5486
<P align=left>bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486, filled histogram) or isotype control antibody (Catalog # <A class=NoLineLink href=<P align=left>Western blot shows lysates of bEnd.3 mouse endothelioma cell line and rat embryonic cortical neuron cells. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

1 Publication
NB110-55290
Western Blot: OPA1 Antibody [NB110-55290] - Total protein from Human HeLa cells, Mouse MEF cells and Rat Brain was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST.  The membrane was probed with 2.0 ug/ml anti-OPA1 in 1% blocking buffer.  Precision Plus Protein All Blue molecular weight markers (BioRad) were detected with 1 ug/ml Anti-Blue Marker antibody (NBP2-33376).  The protein ladder was detected with an anti-mouse HRP secondary antibody and OPA1 with an anti-rabbit HRP secondary antibody using chemiluminescence.Immunohistochemistry: OPA1 Antibody [NB110-55290] - Staining in prostatic smooth muscle and glandular epithelium. Human Prostate 40X magnification.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

     2 Reviews

14 Publications
215-GM/CF
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human GM-CSF (Catalog # 215-IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human

186 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in human cell line A-431.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining of human lymph node shows absence of immunoreactivity in lymphoid tissue (negative control).

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

664-LI/CF
<p align=<P align=left>Recombinant Human LIGHT/TNFSF14 (Catalog # 664-LI/CF) stimulates cell proliferation in HUVEC human umbilical vein endothelial cells. The ED<SUB>50</SUB> is 1-4 ng/mL.</P>


Species Human

10 Publications
NB100-2357
Western Blot: MED12 Antibody [NB100-2357] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. NB100-2357 used for WB at 0.1 mcg/ml (A) and at 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B).Western Blot: MED12 Antibody [NB100-2357] - Detection of Human and Mouse Med12 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Med12 antibody NB100-2357 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Rabbit Polyclonal
Species Human, Mouse, Primate
Applications WB, IHC-P, IP

11 Publications
NBP1-47974
Western Blot: PMEL17/SILV Antibody (10E5) [NBP1-47974] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMEL17/SILV(Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMEL17/SILV.Immunocytochemistry/Immunofluorescence: PMEL17/SILV Antibody (10E5) [NBP1-47974] Staining of COS7 cells transiently transfected by pCMV6-ENTRY PMEL17/SILV.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, ICC/IF, IHC

NB300-141
Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - ICC-IF analysis of mixed neuron-glial cultures using GFAP antibody NB300-141 (red) and Vimentin antibody NB300-223 (green). The fibroblastic cells contain only Vimentin and so are green.  The astrocytes contain either Vimentin and GFAP (appearing golden) or predominantly GFAP (appearing red). Blue is nuclear DNA stain.Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - Rat neurons stained with Neurofilament Heavy antibody NB300-217 (red) and GFAP antibody NB300-141 (green).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     4 Reviews

32 Publications
NBP2-24567
Western Blot: NS1-BP Antibody [NBP2-24567] - Analysis of Influenza A NS in a partial recombinant fusion protein containing amino acids DQKLGDAPFLDRLRRD using this antibody (1 ug/ml).  Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Rabbit Polyclonal
Species Human
Applications WB

210-TA/CF
Recombinant Human TNF-alpha  (Catalog # 210‑TA/CF) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.1 µg/lane of Recombinant Human TNF-alpha  was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.


Species Human

428 Publications
NBP2-13883
Western Blot: CDP/CUTL1 Antibody [NBP2-13883] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted)Immunocytochemistry/Immunofluorescence: CDP/CUTL1 Antibody [NBP2-13883] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & the Golgi apparatus.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

1 Publication
NBP1-70650
Western Blot: ND6 Antibody [NBP1-70650] - Human Lung lysate, concentration 0.2-1 ug/ml.

Rabbit Polyclonal
Species Human
Applications WB

NBP1-85841
Western Blot: OAS3 Antibody [NBP1-85841] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: OAS3 Antibody [NBP1-85841] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC


Related Genes

Disorder Of The Optic Nerve has been researched against:

Related PTMs

Disorder Of The Optic Nerve has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Disorder Of The Optic Nerve is also known as Disorder Of Optic Nerve, Neuropathies, Optic, Neuropathy, Optic, Optic Nerve Disease, Optic Nerve Diseases.