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Dentatorubral-pallidoluysian Atrophy: Disease Bioinformatics

Research of Dentatorubral-pallidoluysian Atrophy has been linked to Atrophy, Ataxia, Neurodegenerative Disorders, Myoclonic Epilepsies, Progressive, Ataxia, Spinocerebellar. The study of Dentatorubral-pallidoluysian Atrophy has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Dentatorubral-pallidoluysian Atrophy include Pathogenesis, Cell Death, Localization, Transport, Neuron Death. These pathways complement our catalog of research reagents for the study of Dentatorubral-pallidoluysian Atrophy including antibodies and ELISA kits against ATN1, ATXN3, ATXN1, HTT, DENTATORUBRAL PALLIDOLUYSIAN ATROPHY.

Dentatorubral-pallidoluysian Atrophy Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Dentatorubral-pallidoluysian Atrophy below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 705 products for the study of Dentatorubral-pallidoluysian Atrophy that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NBP1-32083
Western Blot: Ataxin-3 Antibody [NBP1-32083] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Ataxin 3 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Ataxin-3 Antibody [NBP1-32083] - SK-N-SH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Ataxin 3 protein stained by Ataxin 3 antibody  diluted at 1:250.Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP1-42657
Western Blot: Ataxin 7 Antibody [NBP1-42657] - Whole cell lysate (5, 15 and 50 ug) from 293T cells. Antibody used at 0.4 ug/ml.

Rabbit Polyclonal
Species Human
Applications IP (-), WB

1 Publication
NBP1-88711
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebellum, cerebral cortex, fallopian tube and prostate using Anti-BAIAP2 antibody NBP1-88711 (A) shows similar protein distribution across tissues to independent antibody (B).Western Blot: BAIAP2 Antibody [NBP1-88711] - Analysis in rat cell line NBT-II.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
NBP1-90044
Immunohistochemistry-Paraffin: ATN1 Antibody [NBP1-90044] - Analysis in human cerebral cortex and liver tissues. Corresponding ATN1 RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: ATN1 Antibody [NBP1-90044] - Staining of human cell line U-251 MG shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NBP1-90063
Immunohistochemistry-Paraffin: Ataxin-2 Antibody [NBP1-90063] - Analysis in human testis and skeletal muscle tissues. Corresponding Ataxin-2 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Ataxin-2 Antibody [NBP1-90063] - Staining of human cerebellum, cerebral cortex, skeletal muscle and testis using Anti-Ataxin-2 antibody NBP1-90063 (A) shows similar protein distribution across tissues to independent antibody NBP1-90062 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
NB100-56603
Western Blot: Androgen R/NR3C4 [p Ser213, p Ser210] Antibody (156C135.2) [NB100-56603] - Analysis using Azide Free version of NB100-56603. LNCaP cells (passage number 38) were serum-starved for 2 days. After serum starvation, cells were (A) left untreated, (B) treated with 100 ng/ml IGF-1 for 4h, or (C) incubated with 20 um LY294002 for 30 mi

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

14 Publications
NBP2-01770
Western Blot: FMRP Antibody (1C6) [NBP2-01770] Analysis of extracts (35ug) from 9 different cell lines by using anti-FMRP monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunocytochemistry/Immunofluorescence: FMRP Antibody (1C6) [NBP2-01770] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY FMRP.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

1 Publication
NBP2-14336
Western Blot: Ataxin-10 Antibody [NBP2-14336] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: Ataxin-10 Antibody [NBP2-14336] - Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane & cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-56708
Western Blot: Caspase-3 Antibody (31A1067) - (Pro and Active) [NB100-56708] - Image of Caspase-3 Antibody (31A1067) - (Pro and Active).  Whole cell protein from Jurkat cells treated with and without 2 uM staurosporine as indicated was separated on a 4-15% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST.  The membrane was probed with 5 ug/ml anti-Caspase 3 in 1% milk, and detected with an anti-mouse HRP secondary antibody using a Femto sensitivity chemiluminescence reagent.  Note the detection of both pro-caspase 3 at 35 kDa and the cleaved active caspase 3 at 15-17 kDa.Immunohistochemistry-Paraffin: Caspase-3 Antibody (31A1067) - (Pro and Active) [NB100-56708] - Tissue section of human spleen using 1:200 dilution of Caspase-3 antibody (clone 31A1067). The staining was developed with HRP labeled anti-mouse IgG secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin. This Caspase 3 antibody generated primarily a specific cytoplasmic staining in a subset of spleenocytes with some nuclear signal in a few cells.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, EM

     1 Review

161 Publications
NBP2-46667
Western Blot: PPP2R2B Antibody [NBP2-46667] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: PPP2R2B Antibody [NBP2-46667] - Staining of human cell line A-431 shows localization to cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-69894
Human Ataxin 1 ELISA Kit (Colorimetric) - Standard Curve Reference


Species Human
Applications ELISA

NBP2-75531
Western Blot: Huntingtin Antibody (JB89-34) [NBP2-75531] - Western blot analysis of Huntingtin on SH-SY5Y cell lysates using anti-Huntingtin antibody at 1/500 dilution.Immunohistochemistry-Paraffin: Huntingtin Antibody (JB89-34) [NBP2-75531] - Analysis of paraffin-embedded rat brain tissue using anti-Huntingtin antibody. Counter stained with hematoxylin.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NBP3-03570
Western Blot: Ly-6E Antibody [NBP3-03570] - Analysis of extracts of various cell lines, using Ly-6E antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.Immunocytochemistry/Immunofluorescence: Ly-6E Antibody [NBP3-03570] - Analysis of L929 cells using LY6E Rabbit pAb at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. Ly-6E antibody

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF

NBP2-93513
Western Blot: PEO1 Antibody [NBP2-93513] - Analysis of extracts of MCF-7 cells, using PEO1 .Exposure time: 90s.Immunocytochemistry/Immunofluorescence: PEO1 Antibody [NBP2-93513] - Analysis of A549 cells using PEO1 . Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

NBP2-93821
Western Blot: Puratrophin-1 Antibody [NBP2-93821] - Analysis of extracts of rat testis, using Puratrophin-1 .Exposure time: 90s.

Rabbit Polyclonal
Species Human, Rat
Applications WB

NBP2-95183
Western Blot: TATA binding protein TBP Antibody [NBP2-95183] - Analysis of extracts of Rat skeletal muscle, using TBP antibody  at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit. Exposure time: 90s.Immunocytochemistry/Immunofluorescence: TATA binding protein TBP Antibody [NBP2-95183] - Analysis of NIH/3T3 cells using TATA binding protein TBP . Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF

NBP3-05546
Western Blot: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NBP3-05546] - Different tissue and cell lysates using NBP3-05546 at a dilution of 1:1,000 in green. Left: [1] protein standard, [2] rat brain caudate/putmen region, [3] rat brain striatum region and [4] mouse brain. The prominent band at ~68kDa corresponds to SLC6A4 protein, and lower bands are likely are proteolytic products of SLC6A4. [5] protein standard, [6] non-transfected HEK293 cells and [7] HEK293 cells transfected with an expression construct containing a Myc-DDK tagged full length human SLC6A4 cDNA. The bands between 50-75kDa mark in the transfected cells demonstrate overexpression of SLC6A4, and the band at about 150kDa presumably corresponds to an aggregated form of SLC6A4. The blot was probed with mouse mAb to GAPDH at a dilution of 1:5,000, in red, which reveals the single band at ~37kDa in both transfected and non-transfected cells. Note that HEK293 cells express endogenously (7).Immunocytochemistry/Immunofluorescence: SLC6A4/5-HTTLPR/Serotonin transporter Antibody [NBP3-05546] - Immunofluorescent analysis of a rat brain section stained with SLC6A4/5-HTTLPR/Serotonin transporter Antibody in green and counterstained with chicken polyclonal antibody to tyrosine hydroxylase in red. The axons of serotoninergic neurons course throughout the section but are clearly distinct from the chatacholinergic processes and cell bodies revealed with the TH antibody. The blue stain reveals DNA in cell nuclei.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF


Related Genes

Dentatorubral-pallidoluysian Atrophy has been researched against:

Related PTMs

Dentatorubral-pallidoluysian Atrophy has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Dentatorubral-pallidoluysian Atrophy is also known as dentatorubral-pallidoluysian atrophy, drpla, naito-oyanagi disease, nod, ataxia, chorea, seizures, and dementia, dentatorubro-pallidoluysian atrophy, dentatorubropallidoluysian atrophy, epilepsies, myoclonic.