Childhood Chronic Myelogenous Leukemia is the most common of childhood chronic myeloproliferative disorders, however it only makes up 10% to 15% of childhood myeloid leukemia. Patients diagnosed tend to be 6 years of age or older, however, it has been diagnosed in very young children as well. Chronic Myelogenous Leukemia is a clonal panmyelopathy that includes all hematopoietic cell linages. White blood cell levels are extremely elevated while the bone marrow does not have increased levels of leukemic blasts when the disease is chronic. Chronic Myelogenous Leukemia is almost always associated with the presence of the Philadelphia chromosome (a translocation between chromosomes 9 and 22) causing a fusion of the BCR and ABL genes.
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Childhood Chronic Myelogenous Leukemia, Bcr-abl1 Positive below!
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We have 813 products for the study of Childhood Chronic Myelogenous Leukemia, Bcr-abl1 Positive that can be applied to Flow Cytometry, Western Blot, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.