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Central Nervous System Sensitization: Disease Bioinformatics

Research of Central Nervous System Sensitization has been linked to Pain, Hyperalgesia, Chronic Pain, Neuralgia, Inflammation. The study of Central Nervous System Sensitization has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Central Nervous System Sensitization include Sensitization, Hypersensitivity, Reflex, Pathogenesis, Synaptic Transmission. These pathways complement our catalog of research reagents for the study of Central Nervous System Sensitization including antibodies and ELISA kits against TAC1, BDNF, CALCA, MAPK1, FOS.

Central Nervous System Sensitization Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Central Nervous System Sensitization below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 2174 products for the study of Central Nervous System Sensitization that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

RPL5 Antibody
NBP1-31413
Western Blot: RPL5 Antibody [NBP1-31413] - Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with RPL5 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: RPL5 Antibody [NBP1-31413] - HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RPL5 protein stained by RPL5 antibody diluted at 1:500. Blue: Hoechst 33342 staining.Scale bar = 10 um.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
ERK2 Antibody (OTI6E5)
NBP1-47842
Western Blot: ERK2 Antibody (6E5) [NBP1-47842] - Analysis of extracts (35ug) from 9 different cell lines by using anti-ERK2 monoclonal antibody.Immunohistochemistry-Paraffin: ERK2 Antibody (6E5) [NBP1-47842] - Endometrium tissue within the normal limits using antiMAPK1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min,Dilution 1:50)

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

PP5 Antibody (OTI2E12)
NBP1-47927
Western Blot: PP5 Antibody (2E12) [NBP1-47927] Analysis of extracts (35ug) from 9 different cell lines by using anti-PP5 monoclonal antibody.Immunocytochemistry/Immunofluorescence: PP5 Antibody (2E12) [NBP1-47927] - Immunofluorescent staining of HT29 cells using anti-PP5 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

Aurora A Antibody - BSA Free
NBP1-51843
Immunocytochemistry/Immunofluorescence: Aurora A Antibody [NBP1-51843] - HeLa cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti- (NBP1-51843) at 2 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Alpha tubulin (DM1A) NB100-690 was used as a co-stain at a 1:1000 dilution overnight at 4C and detected with an anti-mouse Dylight 550 (Red) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.Simple Western: Aurora A Antibody [NBP1-51843] - Simple Western lane view shows a specific band for Aurora A in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230kDa separation system.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

     1 Review

6 Publications
PPT1 Antibody
NBP1-85563
Western Blot: PPT1 Antibody [NBP1-85563] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-PPT1 antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.Immunohistochemistry-Paraffin: PPT1 Antibody [NBP1-85563] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
COX-2 Antibody
NB100-689
Immunohistochemistry-Paraffin: COX-2 Antibody [NB100-689] - Formalin fixed paraffin embedded colon carcinoma stained with COX-2 antibody (NB100-689).Simple Western: COX-2 Antibody [NB100-689] - Simple Western lane view shows a specific band for COX2 in 1.0 mg/ml of Rat Brain at an antibody concentration of 1:100. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Image provided through customer review.

Rabbit Polyclonal
Species Human, Rat
Applications WB, Simple Western, IHC

     1 Review

33 Publications
PCNA associated factor Antibody (3C11-1F11)
H00009768-M01
Western Blot: PCNA associated factor Antibody (3C11-1F11) [H00009768-M01] - Western Blot analysis of KIAA0101 expression in JAR ( Cat # L003V1 ).Immunocytochemistry/Immunofluorescence: PCNA associated factor Antibody (3C11-1F11) [H00009768-M01] - Analysis of monoclonal antibody to KIAA0101 on HeLa cell. Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

6 Publications
EphB2 Antibody [Unconjugated]
AF467
Simple Western lane view shows lysates of COLO 205 human colorectal adenocarcinoma cell line and MBA‑MB‑468 human breast cancer cell line, loaded at 0.2 mg/mL. A specific band was detected for EphB2 at approximately 139 and 146 kDa (as indicated) using 20 µg/mL of Goat Anti-Human/Mouse EphB2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF467) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class= Western blot shows 25 ng of Recombinant Human EphB2 Fc Chimera (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     5 Reviews

41 Publications
EN-RAGE/S100A12 Antibody [Unconjugated]
AF1052
Simple Western lane view shows lysates of human tonsil, loaded at 0.2 mg/mL. A specific band was detected for EN‑RAGE/S100A12 at approximately 11 kDa (as indicated) using 10 µg/mL of Goat Anti-Human EN‑RAGE/S100A12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1052) . This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.Western blot shows lysate of human granulocytes. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human EN‑RAGE/S100A12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1052) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, Simple Western, Flow

     3 Reviews

2 Publications
Substance P [Biotin]
KGE007
Substance P [Biotin] Substance P [Biotin]


Species Multi-Species
Applications ELISA

33 Publications
IL-6 [HRP]
D6050
IL-6 [HRP] IL-6 [HRP]


Species Human
Applications ELISA

709 Publications
TNF-alpha [Unconjugated]
210-TA
1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

743 Publications
NDOR1 Antibody (OTI1E3)
NBP2-45856
Western Blot: NDOR1 Antibody (OTI1E3) [NBP2-45856] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NDOR1.Immunohistochemistry: NDOR1 Antibody (OTI1E3) [NBP2-45856] - Analysis of Human liver tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Mouse monoclonal
Species Human, Mouse, Canine
Applications WB, ICC/IF, IHC

c-Fos Antibody (2H2)
NBP2-50037
Western Blot: c-Fos Antibody (2H2) [NBP2-50037] - Top panel: Analysis of c-Fos expression in HeLa cells using NBP2-50037. Lane 1: HeLa cells were serum-starved for 36 hours. Lane 2: Serum-starved HeLa cells were stimulated with 20% FBS (fetal bovine serum) for 2 hours. NBP2-50037 recognizes bands in the range of 50-65 kDa, which represent multiple forms of c-Fos. Serum starvation attenuates c-Fos expression, while 20% FBS strongly stimulates c-Fos expression. Bottom panel: Blot was stripped and probed with monoclonal antibody against GAPDH (NB300-221) used as loading control.Immunocytochemistry/Immunofluorescence: c-Fos Antibody (2H2) [NBP2-50037] - Section of rat hippocampus stained with mouse monoclonal antibody to c-FOS NBP2-50037 in red and counterstained with rabbit polyclonal antibody to FOX3/NeuN. DAPI reveals nuclei of neurons and glia in blue. The hippocampal neurons stain green for FOX3/NeuN and a few also are expressing c-FOS, and so appear orange. These cells were spontaneously active at the time the animal was sacrificed.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

13 Publications
BDNF [Unconjugated]
248-BDB
2 μg/lane of Recombinant Human BDNF was resolved with SDS-PAGE underreducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Bluestaining, showing bands at 13-14 kDa and 11-12 kDa, respectively. Recombinant Human BDNF (Catalog # 248-BDB) stimulates cell proliferation in the BaF mouse pro-B cell line transfected with TrkB. The ED<sub>50</sub> for this effect is 0.2‑2 ng/mL.


Species Human, Mouse, Rat
Applications Bind, BA

210 Publications
Procalcitonin Antibody (44D9)
NB120-14817

Mouse Monoclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

     1 Review

8 Publications
NMDAR1 Antibody (R1JHL)
NB300-118
Western Blot: NMDAR1 Antibody (R1JHL) [NB300-118] - 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~120 kDa NR1 subunit of the NMDA receptor.Western Blot: NMDAR1 Antibody (R1JHL) [NB300-118] - The blots show the examples of immunobands against NMDAR1 and beta-actin antibodies on the membrane, which was performed on the membrane protein prepared from the lumbar spinal cords of the offspring (P14) rats in different groups. Image collected and cropped by CiteAb from the following publication (http://www.jbiomedsci.com/content/18/1/64) licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     14 Reviews

18 Publications

Related Genes

Central Nervous System Sensitization has been researched against:

Related Pathways

Central Nervous System Sensitization has been linked to:

Related Diseases

Central Nervous System Sensitization has been studied in relation to diseases such as:

Related PTMs

Central Nervous System Sensitization has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Central Nervous System Sensitization is also known as Central Sensitisation, Central Sensitization, Central Sensitizations, Sensitization, Central.