Granulosa cell tumors are tumors that arise in the granulosa cells, primarily occurring in the ovary but may develop in the testicles as well. These cell tumors account for 2% of all ovarian tumors as they include theca cell and fibroblast tumors as part of a sex cord-stromal category. 95% of granulosa cell tumors occur in adults, mostly in postmenopausal women. Tumors with theca cells are always benign, thus carry a promising outcome. However, granulosa cell tumors should be thought to be like malignant tumors and treated accordingly. It is believed that most of granulosa cell tumors (97%) are caused by a mutation on the FOXL2 gene.
Cell Cancer, Granulosa Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cell Cancer, Granulosa below!
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