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Cavernous Hemangioma Of Brain: Disease Bioinformatics

A cavernous brain hemangioma is a type of blood vessel malformation the results in blood-filled cavities around the tissues of the brain. Cavernous brain hemangiomas are lesions that arise from the tiny vessels that separate the arterial system from the venous system of the brain. It is also possible that these cavernous hemangiomas are slow growing tumors of capillary blood vessels. The lesions are benign, and no treatment is necessary unless there is evidence of a hemorrhage or the occurrence of seizures. Once there is a hemorrhage of the hemangioma, it tends to happen again, which leads to very rapid neurological decline, as cell function is lost every time there is bleeding into the tissues. When hemorrhaging does occur, the treatment options are to surgically remove the cavernous brain hemangioma, or to treat it with radiation therapy.

Cavernous Hemangioma Of Brain Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cavernous Hemangioma Of Brain below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1622 products for the study of Cavernous Hemangioma Of Brain that can be applied to Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY licence.Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

23 Publications
NB100-292
Western Blot: TERF2IP Antibody [NB100-292] - Detection of Human RAP1 by Western Blot. Samples: Whole cell lysate (15 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-RAP1 antibody NB100-292 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunohistochemistry-Paraffin: TERF2IP Antibody [NB100-292] - Sections of human lung carcinoma.~~ Antibody: Affinity purified rabbit anti-RAP1 used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

19 Publications
NBP1-58359
Western Blot: RhoD Antibody [NBP1-58359] - Transfected 293T, Antibody Titration: 0.2-1 ug/mlImmunohistochemistry: RhoD Antibody [NBP1-58359] - Human Liver Tissue Observed Staining: Cytoplasm in sinusoids of liver Primary Antibody Concentration: 1 : 100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1 : 200 Magnification: 20X Expos

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-87833
Immunohistochemistry-Paraffin: MST3 Antibody [NBP1-87833] - Staining of human liver, skin, small intestine and testis using Anti-STK24 antibody NBP1-87833 (A) shows similar protein distribution across tissues to independent antibody NBP1-87834 (B).Western Blot: MST3 Antibody [NBP1-87833] - Analysis using Anti-STK24 antibody NBP1-87833 (A) shows similar pattern to independent antibody NBP1-87834 (B).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

     1 Review

2 Publications
NBP2-01134
Western Blot: CCM2 Antibody (1E9) [NBP2-01134] Analysis of extracts (35ug) from 9 different cell lines by using anti-CCM2 monoclonal antibody.Immunohistochemistry-Paraffin: CCM2 Antibody (1E9) [NBP2-01134] - Staining of paraffin-embedded Human lymph node tissue using anti-CCM2 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-22527
Western Blot: RAP1A Antibody (1D4-1A3) [NBP2-22527] - Analysis of 25 ug of various whole cell lysate per well.Immunocytochemistry/Immunofluorescence: RAP1A Antibody (1D4-1A3) [NBP2-22527] - Analysis of Rap1 (green) in HeLa cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% BSA/TBST for 15 minutes at room temperature. Cells were probed with a Rap1 monoclonal antibody at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488-conjugated goat anti-mouse IgG secondary antibody at a dilution of 1:400 for 30 minutes at room temperature. Nuclei (blue) were stained with Hoechst 33342 dye.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
AF887
Western blot shows lysates of NIH‑3T3 mouse embryonic fibroblast cell line untreated (-) or treated (+) with 100 ng/mL Human PDGF (Catalog #<A class=NoLineLink href=Simple Western lane view shows lysates of MCF‑7 human breast cancer cell line and A549 human lung carcinoma cell line untreated (-) or treated (+) with 100 ng/mL Recombinant Human IGF‑I (Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

28 Publications
AF6805
Western blot shows lysates of human small intestine tissue, human testis tissue, human spleen tissue, and human prostate tissue. PVDF Membrane was probed with 2 µg/mL of Sheep Anti-Human ICAP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6805) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=ICAP-1 was detected in immersion fixed paraffin-embedded sections of human colon cancer tissue using Sheep Anti-Human ICAP-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6805) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications WB, IHC

2 Publications
AF370

Goat Polyclonal
Species Human
Applications WB, IP

     1 Review

12 Publications
DVE00
 VEGF [HRP] VEGF [HRP]


Species Human
Applications ELISA

617 Publications
DNDG00
 Endoglin/CD105 [HRP] Endoglin/CD105 [HRP]


Species Human
Applications ELISA

36 Publications
8475-OM/CF


Species Human
Applications BA

1 Publication
NBP2-47405
Immunohistochemistry-Paraffin: KRIT1 Antibody [NBP2-47405] - Staining of human liver shows no cytoplasmic positivity in hepatocytes.Immunohistochemistry: KRIT1 Antibody [NBP2-47405] - Staining of human small intestine shows distinct positivity in a subset of vessels.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP2-59690
Western Blot: Rhodopsin Antibody (4D2) [NBP2-59690] - Western Blot analysis of Human A549 cells showing detection of ~38.9kDa Rhodopsin protein using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Lane 1: MW ladder. Lane 2: Human A549 Cells 15 ug). Load: 15 ug. Block: 5% Skim Milk Powder in TBST. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000 for 2.5 hours at RT with shaking . Secondary Antibody: Goat anti-mouse IgG:HRP at 1:1000 for 1 hour at RT with shaking . Color Development: Chemiluminescent for HRP (Moss) for 5 min in RT. Predicted/Observed Size: ~38.9kDa. Other Band(s): Band appears at ~75 kDa indicating detection of the Rhodopsin dimer.Immunohistochemistry: Rhodopsin Antibody (4D2) [NBP2-59690] - Immunohistochemistry analysis using Mouse Anti-Rhodopsin Monoclonal Antibody, Clone 4D2 (NBP2-59690). Tissue: retina. Species: Mouse. Primary Antibody: Mouse Anti-Rhodopsin Monoclonal Antibody (NBP2-59690) at 1:1000. Secondary Antibody: FITC Goat Anti-Mouse (green). Counterstain: DAPI (blue) nuclear stain. Localization: Staining of photoreceptor outer segment (OS). Other layers of the retina: IS  inner segment; ONL  outer nuclear layer; OPL  outer plexiform layer; INL  inner nuclear layer; IPL  inner plexiform layer; GCL  ganglion cell layer..

Mouse Monoclonal
Species Amphibian, Avian, Fish
Applications WB, ELISA, ICC/IF

     1 Review

3 Publications
NB100-91273
Western Blot: RhoA Antibody [NB100-91273] - Rat spinal cord lysate using Rabbit antibody to Transforming protein RhoA: whole serum at 1:2000 dilution. One single band is detected.Immunocytochemistry/Immunofluorescence: RhoA Antibody [NB100-91273] - Rat trigeminal at 1:500 dilution using Rabbit antibody to Transforming protein RhoA: whole serum (NB100-91273, in red), Sheep antibody to extracellular, N-terminal part of Sortilin: whole serum (NB100-98771, in green), DAPI counter stained appearing in blue.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

4 Publications
NBP2-67360
Knockout Validated: ERK2 Antibody (SZ25-01) [NBP2-67360] - Lysates of HeLa WT and MAPK1 KO were prepared, and 30 ug of protein were processed for immunoblot with the indicated Mitogen-activated protein kinase 1 antibodies. The Ponceau stained transfers of each blot are shown. Antibody dilution used: 1/1000. Predicted band size: 41 kDa. Image, protocol and testing courtesy of YCharOS Inc. (ycharos.com).Knockout Validated: ERK2 Antibody (SZ25-01) [NBP2-67360] - HeLa WT and MAPK1 KO cells were labelled with a green or a far-red fluorescent dye, respectively. WT and KO cells were mixed and plated to a 1:1 ratio on coverslips. Cells were stained with the indicated Mitogen-activated protein kinase 1 antibodies and with the corresponding Alexa-fluor 555 coupled secondary antibody. Acquisition of the green (identification of WT cells), red (antibody staining) and far-red (identification of KO cells) channels was performed. Representative images of the red (grayscale) channels are shown.WT and KO cells are outlined with yellow and magenta dashed line, respectively. Antibody dilution used: 1/1000. Bars = 10 um. Image, protocol and testing courtesy of YCharOS Inc. (ycharos.com).

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

NB100-1004
Western Blot: MST4 Antibody [NB100-1004] - Staining of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Antibody at 0.5 ug/mL. Primary incubated for 1 hour. Detected by chemiluminescence.Immunohistochemistry-Paraffin: MST4 Antibody [NB100-1004] - Staining of paraffin embedded Human Thymus. Antibody at 2.5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Goat Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
H00010494-M01
Western Blot: STK25 Antibody (1G6) [H00010494-M01] - STK25 monoclonal antibody (M01), clone 1G6 Analysis of STK25 expression in HepG2.Western Blot: STK25 Antibody (1G6) [H00010494-M01] - Analysis of STK25 expression in transfected 293T cell line by STK25 monoclonal antibody (M01), clone 1G6.Lane 1: STK25 transfected lysate(48.112 KDa).Lane 2: Non-transfected lysate.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

3 Publications
NBP2-93073
Immunocytochemistry/Immunofluorescence: PDCD10 Antibody [NBP2-93073] - Immunofluorescence analysis of PC-12 cells using PDCD10 Rabbit pAb (NBP2-93073) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.Immunohistochemistry-Paraffin: PDCD10 Antibody [NBP2-93073] - Paraffin-embedded rat spleen using PDCD10 .

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC


Related Genes

Cavernous Hemangioma Of Brain has been researched against:

Related PTMs

Cavernous Hemangioma Of Brain has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Cavernous Hemangioma Of Brain is also known as Brain Cavernous Hemangioma, Brain Cavernous Hemangiomas, Cerebral Capillary Malformations, Cerebral Cavernous Malformation, Cerebral Cavernous Malformations.