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Cavernous Hemangioma Of Brain: Disease Bioinformatics

A cavernous brain hemangioma is a type of blood vessel malformation the results in blood-filled cavities around the tissues of the brain. Cavernous brain hemangiomas are lesions that arise from the tiny vessels that separate the arterial system from the venous system of the brain. It is also possible that these cavernous hemangiomas are slow growing tumors of capillary blood vessels. The lesions are benign, and no treatment is necessary unless there is evidence of a hemorrhage or the occurrence of seizures. Once there is a hemorrhage of the hemangioma, it tends to happen again, which leads to very rapid neurological decline, as cell function is lost every time there is bleeding into the tissues. When hemorrhaging does occur, the treatment options are to surgically remove the cavernous brain hemangioma, or to treat it with radiation therapy.

Cavernous Hemangioma Of Brain Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cavernous Hemangioma Of Brain below! For more information on how to use Laverne, please read the How to Guide.
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Top Research Reagents

We have 1027 products for the study of Cavernous Hemangioma Of Brain that can be applied to Flow Cytometry, Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-47405
Immunohistochemistry: KRIT1 Antibody [NBP2-47405] - Staining of human small intestine shows distinct positivity in a subset of vessels.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-47195
Western Blot: PDCD10 Antibody [NBP1-47195] - K.O. = knock out (completely deleted) K.D. = knock down (not completely deleted) OV. = over expressed in COS1 cells. Figure 2. Western Analysis of anti-human CCM-3. Immunocytochemistry/Immunofluorescence: PDCD10 Antibody [NBP1-47195] - (green) of human foreskin (cryosection of unfixed tissue) with anti-human CCM3 (K5548; dilution 1:50)  A) Note specific staining in the epidermis and in the wall of microvessels. B) Negative control of a consecutive section. Nuclei counterstained with Dapi (blue). Specimen provided by Prof. Dr. J. Wilting,

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP1-86729
Western Blot: CCM2 Antibody [NBP1-86729] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunohistochemistry-Paraffin: CCM2 Antibody [NBP1-86729] - Staining in human lymph node and pancreas tissues using anti-CCM2 antibody. Corresponding CCM2 RNA-seq data are presented for the same tissues.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

NBP2-22527
Western Blot: RAP1A Antibody (1D4-1A3) [NBP2-22527] - Analysis of 25 ug of various whole cell lysate per well.Immunocytochemistry/Immunofluorescence: RAP1A Antibody (1D4-1A3) [NBP2-22527] - Analysis of Rap1 (green) in HeLa cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% BSA/TBST for 15 minutes at room temperature. Cells were probed with a Rap1 monoclonal antibody at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488-conjugated goat anti-mouse IgG secondary antibody at a dilution of 1:400 for 30 minutes at room temperature. Nuclei (blue) were stained with Hoechst 33342 dye.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP1-32670
Western Blot: STK25 Antibody [NBP1-32670] - Sample (30 ug of whole cell lysate)A: Hela S310% SDS PAGE, antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: STK25 Antibody [NBP1-32670] - Analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

AF6805
Western blot shows lysates of human small intestine tissue, human testis tissue, human spleen tissue, and human prostate tissue. PVDF Membrane was probed with 2 µg/mL of Sheep Anti-Human ICAP‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6805) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <A class=NoLineLink href=ICAP-1 was detected in immersion fixed paraffin-embedded sections of human colon cancer tissue using Sheep Anti-Human ICAP-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6805) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications WB, IHC

1 Publication
295-OM


Species Human

     1 Review

44 Publications
NBP1-87833
Western Blot: MST3 Antibody [NBP1-87833] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: MST3 Antibody [NBP1-87833] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoli & cytosol.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

2 Publications
AF887
Western blot shows lysates of NIH‑3T3 mouse embryonic fibroblast cell line untreated (-) or treated (+) with 100 ng/mL Human PDGF (Catalog #<A class=NoLineLink href=Akt phosphorylated at S473 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using Rabbit Anti-Human/Mouse/Rat Phospho-Akt (S473) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF887) at 10 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, IHC

18 Publications
NBP2-25159
Western Blot: Rhodopsin Antibody (A531) [NBP2-25159] - Blot of bovine retinal extracts. The antibody stains a band corresponing to retinal Rhodopsin at about 35kDa. Bands about 70 kDa and 140 kDa are aggregated forms of Rhodopsin. Note, due to the highly hydrophobic nature of Rhodopsin, it is important not to boil a sample containing it in SDS-PAGE sample buffer, as this will result in more extensive aggregation of the Rhodopsin protein.Immunocytochemistry/Immunofluorescence: Rhodopsin Antibody (A531) [NBP2-25159] - Pig retinal section stained with NBP2-25159 (green) and counterstained with rabbit polyclonal antibody to NF-M NB300-133 (red) and DNA (blue). Rhodopsin is most abundant in the outer segments of retina (OS), NF-M is abundant in the optic nerve fiber layer (ONFL), but seen in processes and neurons in other regions also. Other layers are pigmented epithelium (PE), outer and inner nuclear layers (ONL, INL), outer and inner plexiform layers (OPL, IPL) and ganglion cell layer (GCL).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

1 Publication
NBP2-01462
Western Blot: RhoD Antibody (2F7) [NBP2-01462] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RhoD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RhoD.Immunocytochemistry/Immunofluorescence: RhoD Antibody (2F7) [NBP2-01462] Staining of COS7 cells transiently transfected by pCMV6-ENTRY RhoD.

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

H00051765-M02
Western Blot: MST4 Antibody (7H4) [H00051765-M02] - RP6-213H19 1 monoclonal antibody (M02), clone 7H4 Analysis of RP6-213H19 1 expression in HeLa.Immunocytochemistry/Immunofluorescence: MST4 Antibody (7H4) [H00051765-M02] - Analysis of monoclonal antibody to RP6-213H19.1 on HeLa cell. Antibody concentration 20 ug/ml.

Mouse Monoclonal
Species Human, Rat
Applications WB, ELISA, ICC/IF

AF1320
  Simple  Western lane view shows lysates of bEnd.3 mouse endothelioma cell line,  loaded at 0.2 mg/mL. A specific band was detected for Endoglin/CD105  at approximately 121 kDa (as indicated) using 5 µg/mL of  Goat Anti-Mouse Endoglin/CD105 Antigen Affinity-purified Polyclonal Antibody  <br>(Catalog # AF1320) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG  Secondary Antibody (Catalog # <a class=  Western  blot shows lysates of bEnd.3 mouse endothelioma cell line and <br>MS‑1  mouse pancreatic islet endothelial cell line. PVDF membrane was probed with  0.5 µg/mL of Goat Anti-Mouse Endoglin/CD105 Antigen  Affinity-purified Polyclonal Antibody (Catalog # AF1320) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, Simple Western, Flow

     3 Reviews

12 Publications
NB100-91273
Western Blot: RhoA Antibody [NB100-91273] - Rat spinal cord lysate using Rabbit antibody to Transforming protein RhoA: whole serum at 1:2000 dilution. One single band is detected.Immunocytochemistry/Immunofluorescence: RhoA Antibody [NB100-91273] - Rat trigeminal at 1:500 dilution using Rabbit antibody to Transforming protein RhoA: whole serum (NB100-91273, in red), Sheep antibody to extracellular, N-terminal part of Sortilin: whole serum (NB100-98771, in green), DAPI counter stained appearing in blue.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Total protein from human THP1 and US-OS cells and mouse Raw264.7 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-NOD2 in 1% non-fat milk in TBST and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

13 Publications
370-AL


Species Human

12 Publications
NB100-292
Western Blot: TERF2IP Antibody [NB100-292] - Detection of Human RAP1 by Western Blot. Samples: Whole cell lysate (15 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-RAP1 antibody NB100-292 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunohistochemistry: TERF2IP Antibody [NB100-292] - Samples: FFPE sections of human lung carcinoma.~~ Antibody: Affinity purified rabbit anti-RAP1 used at a dilution of 1:5,000 (0.2ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

18 Publications

Related Genes

Cavernous Hemangioma Of Brain has been researched against:

Related PTMs

Cavernous Hemangioma Of Brain has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Cavernous Hemangioma Of Brain is also known as Brain Cavernous Hemangioma, Brain Cavernous Hemangiomas, Cerebral Capillary Malformations, Cerebral Cavernous Malformation, Cerebral Cavernous Malformations.