Submit your image related to Diseases to be featured!

Get Social

Submit your Twitter account related to Brain Diseases, Metabolic, Inborn to be featured!

Blogs

Submit your blog on Brain Diseases, Metabolic, Inborn to be featured!

Events

Submit your event on Brain Diseases, Metabolic, Inborn to be featured!

Videos

Submit your video on Brain Diseases, Metabolic, Inborn to be featured!

Charities

Submit your charity on Brain Diseases, Metabolic, Inborn to be featured!

Brain Diseases, Metabolic, Inborn: Disease Bioinformatics

Inborn metabolic brain diseases arise from disturbances in body chemistry due to an alteration in the metabolic cycle. A disturbance in the brain’s chemical environment in the form of a deficiency or the buildup of metabolites leading to the spread of toxins can lead to a metabolic disorder, which can be expressed in many forms such as impaired brain development, cerebral palsy and seizures. Inborn metabolic brain diseases can occur in the fetus due to a nutritional deficiency or alcohol use of the mother. Metabolic brain diseases can also be passed on genetically, typically in an autosomal recessive manner, but can also arise from spontaneous mutations in utero. The majority of metabolic brain diseases occur in infants. Treatment for many metabolic brain diseases is still being researched, but many doctors will attempt to restore the chemical balance of the brain in order to reverse the effects of the symptoms.

Brain Diseases, Metabolic, Inborn Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Brain Diseases, Metabolic, Inborn below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 457 products for the study of Brain Diseases, Metabolic, Inborn that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-48549
Western Blot: GCDH Antibody [NBP2-48549] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: GCDH Antibody [NBP2-48549] - Staining of human cell line U-2 OS shows positivity in mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-14036
Western Blot: GAMT Antibody [NBP2-14036] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissueImmunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB110-39113
Western Blot: Glut1 Antibody [NB110-39113] - Analysis of GLUT1 on A. mouse kidney membrane protein and B. rat kidney membrane protein.Western Blot: Glut1 Antibody [NB110-39113] - Analysis of HeLa lysates using NB110-39113. Image courtesy of Gregg Semenza - publication number 21620138 (PMID).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ChIP, Flow

     6 Reviews

18 Publications
NBP2-49445
Immunocytochemistry/Immunofluorescence: L2HGDH Antibody [NBP2-49445] - Immunofluorescent staining of human cell line MCF7 shows localization to mitochondria.Immunohistochemistry-Paraffin: L2HGDH Antibody [NBP2-49445] - Staining of human duodenum shows strong positivity with a granular a pattern in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

215-GM/CF
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human GM-CSF (Catalog # 215-IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human

205 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-60082
Western Blot: SLC6A8 Antibody [NBP1-60082] - Sample Tissue: Human MDA-MB-435s, Human THP - 1 Antibody Dilution: 1.0 ug/mlImmunohistochemistry: SLC6A8 Antibody [NBP1-60082] - Paraffin Embedded Tissue: Human Muscle Cellular Data: Skeletal muscle cells Antibody Concentration: 4.0 - 8.0 ug/ml Magnification: 400X

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NBP1-32423
Western Blot: SUOX Antibody [NBP1-32423] - Sample (50 ug of whole cell lysate) A: mouse liver 7. 5% SDS PAGE; antibody diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SUOX Antibody [NBP1-32423] - Analysis of methanol-fixed HepG2, using antibody at 1:200 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

NBP1-32550
Western Blot: COX5A Antibody [NBP1-32550] - Sample(30 ug whole cell lysate)A:HeLa S3 B:Hep G2 15% SDS PAGE, antibody diluted at 1:5000.Immunocytochemistry/Immunofluorescence: COX5A Antibody [NBP1-32550] -  A431.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

2 Publications
NBP1-86996
Western Blot: ALDH5A1 Antibody [NBP1-86996] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: ALDH5A1 Antibody [NBP1-86996] - Immunofluorescent staining of human cell line CACO-2 shows localization to mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
NBP2-59438
Western Blot: CPOX Antibody (36B10) [NBP2-59438] - Lane 1: Recombinant protein CPOX, Lane 2: 293T cell lysates, Lane 3: HepG2 cell lysates, Lane 4: A549 cell lysates, Lane 5: Jurkat cell lysates, Lane 6: K562 cell lysates, Lane 7: LnCaP cell lysatesImmunocytochemistry/Immunofluorescence: CPOX Antibody (36B10) [NBP2-59438] - Analysis of CPOX in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CPOX antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NBP2-65875


Species Human

NBP1-81689
Western Blot: ETHE1 Antibody [NBP1-81689] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).Immunocytochemistry/Immunofluorescence: ETHE1 Antibody [NBP1-81689] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & mitochondria.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-24916
Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     1 Review

4 Publications
NBP1-76544
Immunocytochemistry/Immunofluorescence: GLS2 Antibody [NBP1-76544] - of GLS2 in Human Kidney cells. Dilution 20 ug/mL.Immunohistochemistry: GLS2 Antibody [NBP1-76544] - Immunohistochemistry of GLS2 in human kidney tissue with GLS2 antibody at 5 ug/mL.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

2 Publications
NBP2-03107
Western Blot: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] Analysis of extracts (35ug) from 9 different cell lines by using anti-Adenylosuccinate Lyase monoclonal antibody.Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] - Staining of paraffin-embedded Human lymphoma tissue using anti-Adenylosuccinate Lyase mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, Flow, IHC

NBP1-88866
Immunocytochemistry/Immunofluorescence: AGA Antibody [NBP1-88866] - Staining of human cell line U-2 OS shows positivity in vesicles and cytoskeleton (microtubules).Immunohistochemistry-Paraffin: AGA Antibody [NBP1-88866] - Staining of human skeletal muscle shows low expression as expected.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

NBP1-87311
Western Blot: PHGDH Antibody [NBP1-87311] - Analysis in human cell lines SK-MEL-30 and A-549. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-COX4I1.Immunocytochemistry/Immunofluorescence: PHGDH Antibody [NBP1-87311] - Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

6 Publications
NB110-41404
Western Blot: Glutamine Synthetase Antibody [NB110-41404] - Analysis of glutamine synthase. 40ug of lysates from mouse (Lanes M), rat (Lanes R), pig (Lanes P), bovine (Lanes B), or human (Lanes Hu) retina were probed. A 42 kDa band was identified in lysates from retinas of all species.Immunohistochemistry: Glutamine Synthetase Antibody [NB110-41404] - Localization of glutamine synthase in the retina. Paraffin sections of mouse (A, B), rat (C, D, G-I), or human (E, F) retina fixed in 4% paraformaldehyde were reacted with anti-glutamine synthase (red fluorescence staining in B, D, G, I, and brown immuno-peroxidase reaction [using ABC kit and visualization with DAB product in F]. Nuclei in some immunofluorescence experiments (A-D) were stained with DAPI (shown in cyan), and with nuclear fast red in E and F.  On inspection at low magnification, anti- glutamine synthase reacted with a single population of cells extending from the ganglion cell layer (GCL) through the inner nuclear layer (INL). No signal was detected in controls either pre-incubated with 100ug/ml of the immunizing peptide (A) or with pre-immune serum (C, E). The pattern of staining observed in all experiments is typicals. This finding was confirmed by co-localization (indicated by yellow in I) of glutamine synthase (red in G) with antoher marker of glutamine synthase (green in H).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC

     1 Review

2 Publications

Related Genes

Brain Diseases, Metabolic, Inborn has been researched against:

Related PTMs

Brain Diseases, Metabolic, Inborn has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Brain Diseases, Metabolic, Inborn is also known as Inborn Errors Of Metabolism, Brain, Inborn Metabolic Brain Diseases.