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Brain Diseases, Metabolic: Disease Bioinformatics

Metabolic brain diseases arise from disturbances in body chemistry due to an alteration in the metabolic cycle. A disturbance in the brain’s chemical environment in the form of a deficiency or the buildup of metabolites leading to the spread of toxins can lead to a metabolic disorder, which can be expressed in many forms such as impaired brain development, cerebral palsy and seizures. Metabolic brain diseases can occur in the fetus due to a nutritional deficiency or alcohol use of the mother. Metabolic brain diseases can also be passed on genetically, typically in an autosomal recessive manner. The majority of metabolic brain diseases occur in infants and children, but the possibility of a late onset also exists. Treatment for many metabolic brain diseases is still being researched, but many doctors will attempt to restore the chemical balance of the brain in order to reverse the effects of the symptoms.

Brain Diseases, Metabolic Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Brain Diseases, Metabolic below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 1183 products for the study of Brain Diseases, Metabolic that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

NBP2-12553
HPLC: Ceruloplasmin Native Protein [NBP2-12553]


Species Human

215-GM/CF
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.Recombinant Human GM-CSF (Catalog # 215-IL/CF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human

195 Publications
NBP2-42388
Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.

Mouse Monoclonal
Species Human
Applications WB, IHC, IHC-P

NBP2-48549
Western Blot: GCDH Antibody [NBP2-48549] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4Immunocytochemistry/Immunofluorescence: GCDH Antibody [NBP2-48549] - Staining of human cell line U-2 OS shows positivity in mitochondria.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-56503
Western Blot: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - Analysis using the Biotin conjugate of NB100-56503. Detection of Cytochrome C in 15 mgs of HeLa cell lysate using NB100-55775 at 1:1000. A 15 kDa band is detected.Immunocytochemistry/Immunofluorescence: Cytochrome c Antibody (7H8.2C12) [NB100-56503] - p73 was detected in immersion fixed Hela human cell line using Cytochrome C [7H8.2C12] Monoclonal Antibody (Catalog # NB100-56503) at 25 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Staining was observed in the cytoplasm and mitochondria.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

46 Publications
NBP1-87408
Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Analysis in human liver tissue.Immunocytochemistry/Immunofluorescence: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

2 Publications
NB100-65214

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications ELISA, ICC/IF, IHC

NBP2-34260
Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)SDS-Page: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260]

Mouse Monoclonal
Species Human, Mouse, Porcine
Applications WB, Flow, ICC/IF

     4 Reviews

NBP2-24916
Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

     1 Review

4 Publications
NBP1-87730
Western Blot: Methionyl tRNA synthetase Antibody [NBP1-87730] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: Methionyl tRNA synthetase Antibody [NBP1-87730] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
AF8198
 alpha ‑Defensin 1 was detected in formalin fixed paraffin-embedded sections of human small intestine using Sheep Anti-Human  alpha ‑Defensin 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8198) at 1 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=    Recombinant  Human  alpha ‑Defensin 1 protein was serially diluted 2-fold  and captured by Mouse Anti-Human  alpha ‑Defensin 1 Monoclonal  Antibody  (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications ELISA, IHC

NBP1-83790
Western Blot: DHRS4 Antibody [NBP1-83790] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG spImmunocytochemistry/Immunofluorescence: DHRS4 Antibody [NBP1-83790] - Staining of human cell line A-431 shows positivity in nuclear membrane and vesicles.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NB100-1598
Western Blot: CRIPTO Antibody [NB100-1598] - Analysis of Cripto in Dicer knockout mouse embryonic stem cell lysate.Immunocytochemistry/Immunofluorescence: CRIPTO Antibody [NB100-1598] - CRIPTO  antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

2 Publications
NBP1-32244
Western Blot: Calretinin Antibody [NBP1-32244] - Rat tissue extract (50 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Calretinin antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.Immunocytochemistry/Immunofluorescence: Calretinin Antibody [NBP1-32244] - U87-MG cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Calretinin protein stained by Calretinin antibody diluted at 1:200. Blue: Hoechst 33342 staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NB100-56605
Western Blot: Prion protein Antibody [NB100-56605] - Analysis of BSE in (A) recombinant fusion protein containing amino acids 162-170 and (B) fusion partner without these amino acids, using this antibody at 5 ug/ml.

Rabbit Polyclonal
Species Avian, Bovine, Sheep
Applications WB

MAB4909
Western blot shows lysates of human spleen tissue. PVDF Membrane was probed with 2 µg/mL of Mouse Anti-Human CD21 Monoclonal Antibody (Catalog # MAB4909) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 PE‑conjugated Monoclonal Antibody (Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, Flow, CyTOF-ready

1 Publication
AF2009
CD55/DAF was detected in immersion fixed paraffin-embedded sections of human colon cancer tissue using 15 µg/mL Goat Anti-Human CD55/DAF Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2009) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human
Applications WB, IHC

3 Publications

Related Genes

Brain Diseases, Metabolic has been researched against:

Related PTMs

Brain Diseases, Metabolic has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Brain Diseases, Metabolic is also known as Metabolic Encephalopathy, Brain Disease, Metabolic, Brain Metabolic Disorders, Brain Syndrome, Metabolic, Encephalopathies, Metabolic.