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Basal Laminar Drusen (disorder): Disease Bioinformatics

Research of Basal Laminar Drusen (disorder) has been linked to Retinal Drusen, Age Related Macular Degeneration, Retinal Detachment, Choroidal Neovascularization, Glomerulonephritis, Membranoproliferative. The study of Basal Laminar Drusen (disorder) has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Basal Laminar Drusen (disorder) include Pathogenesis, Aging, Pigmentation, Segmentation, Secretion. These pathways complement our catalog of research reagents for the study of Basal Laminar Drusen (disorder) including antibodies and ELISA kits against CFH, RPE, FBLN5, C3, FXN.

Basal Laminar Drusen (disorder) Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Basal Laminar Drusen (disorder) below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 792 products for the study of Basal Laminar Drusen (disorder) that can be applied to Chromatin Immunoprecipitation, Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry from our catalog of antibodies and ELISA kits.

AF4779
Complement Factor H was detected in immersion fixed paraffin-embedded sections of human liver using Goat Anti-Human Complement Factor H Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4779) at 10 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # <A class=

Goat Polyclonal
Species Human
Applications WB, IHC

     2 Reviews

NBP1-56853
Western Blot: RPE Antibody [NBP1-56853] - Human Muscle lysate, concentration 0.2-1 ug/ml.Immunocytochemistry/Immunofluorescence: RPE Antibody [NBP1-56853] - Antibody  0 Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver  Observed Staining: Cytoplasm but only in connective tissue cells in the interlobular septum, very low tissue distribution Primary Antibody

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

NBP2-76929
Western Blot: Fibulin 5/DANCE Antibody [NBP2-76929] - Western blot analysis of Fibulin 5 on human skin tissue lysate using anti-Fibulin 5 antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: Fibulin 5/DANCE Antibody [NBP2-76929] - ICC staining Fibulin 5 in SKOV-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

NB200-540
Flow (Intracellular): Complement C3 Antibody (11H9) [NB200-540] - An intracellular stain was performed on RAW 246.7 cells with Complement C3 (11H9-3-2) antibody NB200-540 (blue) and a matched isotype control NBP2-31382 (orange). Cells were either treated with 3uM Monensin for 3 hours to block the secretion of Complement C3 (B) or grown in normal media (A). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) PE-conjugated secondary antibody (F0102B, R&D Systems).Immunocytochemistry/Immunofluorescence: Complement C3 Antibody (11H9) [NB200-540] - C3 protein fragments deposited on kidney cells of MPL-lpr mouse. Staining with antibody 11H9. Glomerular staining pattern. Fixation in 4% paraformaldehyde in PBS pH 7.4. Vibratome sections of 4 um. Pretreated with 3% hydrogen peroxide for 20 min to quench endogenous peroxidases. Microwaved in antigen unmasking solution for 2-5 minutes as antigen retrieval.

Rat Monoclonal
Species Mouse
Applications Flow, IA, ICC/IF

     2 Reviews

6 Publications
NBP2-59478
Western Blot: Frataxin Antibody (10E11) [NBP2-59478] - Lane 1: 293T cell lysates, Lane 2: Frataxin transfected 293T cell lysatesImmunocytochemistry/Immunofluorescence: Frataxin Antibody (10E11) [NBP2-59478] - Analysis of Frataxin in A549 cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Frataxin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

NB100-2564
Western Blot: FACA/FANCA Antibody [NB100-2564] - Detection of FANC A in transfected COS1 cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

1 Publication
AF5486
<P align=left>Plexin A2 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=<P align=left>Plexin A2 was detected in immersion fixed HUVEC human umbilical vein endothelial cells using Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     1 Review

2 Publications
NBP1-07010

Rabbit Polyclonal
Species Human, Rat, Primate
Applications WB, ELISA, ICC/IF

     1 Review

NB110-60531
Immunohistochemistry-Paraffin: Apolipoprotein E/ApoE Antibody (WUE-4) [NB110-60531] - ApoE was detected in immersion fixed paraffin-embedded sections of human liver using anti-human mouse monoclonal antibody (Catalog # NB110-60531) at 1:200 dilution overnight at 4C. Tissue was stained using the VisuCyte anti-mouse HRP polymer detection reagent (Catalog # VC001) with DAB chromogen (brown) and counterstained with hematoxylin (blue). Images may not be copied, printed or otherwise disseminated without express written permission of Novus Biologicals a bio-techne brand.Western Blot: Apolipoprotein E/ApoE Antibody (WUE-4) [NB110-60531] - ApoE Antibody (WUE-4) [NB110-60531] - Detection of ApoE in human tissue lysate using NB110-60531. Lane 1: liver Lane 2: brain

Mouse Monoclonal
Species Human, Mouse, Rat (Negative)
Applications WB, ELISA, Flow

     2 Reviews

18 Publications
NBP1-89985
Western Blot: Complement Factor B Antibody [NBP1-89985] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.Immunocytochemistry/Immunofluorescence: Complement Factor B Antibody [NBP1-89985] - Staining of human cell line ASC TERT1 shows localization to endoplasmic reticulum. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

5 Publications
MAB1936

Mouse Monoclonal
Species Human
Applications WB, IP

     2 Reviews

1 Publication
NBP2-57871
Western Blot: Fibulin-3/EFEMP1 Antibody [NBP2-57871] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.Immunohistochemistry-Paraffin: Fibulin-3/EFEMP1 Antibody [NBP2-57871] - Staining of human liver shows low positivity in hepatocytes.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

NB300-137
Western Blot: Peripherin Antibody [NB300-137] - Analysis of tissue and cell lysates using Peripherin antibody, dilution 1:10000 in green: [1] protein standard, [2] rat spinal cord, [3] mouse spinal cord, [4] pig spinal cord, [5] cow spinal cord, [6] SH-SY5Y cells and [7] PC12 cells. The major band at ~57kDa corresponds to the major peripherin protein isoform, while other bands presumably represent protein products of alternate transcripts of the peripherin gene.Immunocytochemistry/Immunofluorescence: Peripherin Antibody [NB300-137] - Analysis of the widely used rat pheochromocytoma PC12 cell line stained with rabbit polyclonal Periphren antibody, dilution 1:2000 (Green). Hoechst staining of nuclear DNA (Blue). Peripherin, one of the Class III family of intermediate filament subunit proteins, is a major component of the PC12 cell forming a perinuclear cap, with some filaments visible in the cytoplasm.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     1 Review

6 Publications
NBP1-88115
Immunocytochemistry/Immunofluorescence: Fibulin 2 Antibody [NBP1-88115] - Staining of human cell line BJ shows localization to plasma membrane. Antibody staining is shown in green.Immunohistochemistry-Paraffin: Fibulin 2 Antibody [NBP1-88115] - Staining of human urinary bladder shows strong positivity in connective tissue.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
NBP2-67375
Western Blot: ERG Antibody (SP06-04) [NBP2-67375] - Analysis of ERG on Jurkat cell lysates using anti-ERG antibody at 1/1,000 dilution.Immunocytochemistry/Immunofluorescence: ERG Antibody (SP06-04) [NBP2-67375] - Staining ERG in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, ChIP, ICC/IF

NBP1-26612
Western Blot: MID1 Antibody [NBP1-26612] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at 1 ug/ml.

Rabbit Polyclonal
Species Human
Applications IP (-), WB

1 Publication
NB100-75341
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-AMD1 )ELISA: AMD1 Antibody [NB100-75341] - Direct Elisa Test. Protein as test antigen. Affi-pure IgY as primary antibody and Goat anti-IgY HRP as 2nd antibody. Fixed amount of antigen (5 ug/ml) and serial dilutions of antibody. ( anti-AMD1 )

Chicken Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA

H00002188-B01P
Western Blot: FANCF Antibody [H00002188-B01P] - Analysis of FANCF expression in transfected 293T cell line by FANCF polyclonal antibody.  Lane 1: FANCF transfected lysate(41.14 KDa). Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: FANCF Antibody [H00002188-B01P] - Analysis of purified antibody to FANCF on HeLa cell. (antibody concentration 10 ug/ml)

Mouse Polyclonal
Species Human
Applications WB, ICC/IF

1 Publication
NBP1-30032
Western Blot: ABCA4 Antibody (3F4) [NBP1-30032] - Characterization of ABCA4 mRNA expression and western blot analyses of ABCA4 protein levels in the canine retina. Western blot analyses of ABCA4 (above), GAPDH (middle), and RHO (below) protein levels in retinal tissue of dogs with the three different genotypes. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pgen.1007873), licensed under a CC-BY licence.Immunohistochemistry: ABCA4 Antibody (3F4) [NBP1-30032] - Fluorescence histochemistry of ABCA4, cone photoreceptors, and autofluorescence in the canine retina. Fluorescence micrographs showing ABCA4 expression (red), FITC-conjugated peanut agglutinin (PNA, green), and DAPI nuclear staining (blue) in heterozygous (ABCA4+/-) retina. PNA labels cone photoreceptors. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pgen.1007873), licensed under a CC-BY licence.

Mouse Monoclonal
Species Human, Mouse, Bovine
Applications WB, ICC/IF, IHC

4 Publications
NBP2-45731
Western Blot: beta-Galactosidase-1/GLB1 Antibody (OTI1C9) [NBP2-45731] - Analysis of extracts (35ug) from 9 different cell lines by using anti-GLB1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunohistochemistry: beta-Galactosidase-1/GLB1 Antibody (1C9) [NBP2-45731] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Mouse Monoclonal
Species Human, Canine, Monkey
Applications WB, IHC, IHC-P

2 Publications

Related Genes

Basal Laminar Drusen (disorder) has been researched against:

Related Pathways

Basal Laminar Drusen (disorder) has been linked to:

Alternate Names

Basal Laminar Drusen (disorder) is also known as Basal Laminar Drusen, Cuticular Drusen.