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Anophthalmos: Disease Bioinformatics

Research of Anophthalmos has been linked to Microphthalmos, Congenital Abnormality, Eye Abnormalities, Congenital Ocular Coloboma (disorder), Cleft Palate. The study of Anophthalmos has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Anophthalmos include Enucleation, Eye Development, Pathogenesis, Ossification, Pigmentation. These pathways complement our catalog of research reagents for the study of Anophthalmos including antibodies and ELISA kits against SOX2, OTX2, VSX2, RAX, PAX6.

Anophthalmos Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Anophthalmos below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 781 products for the study of Anophthalmos that can be applied to Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Chromatin Immunoprecipitation (ChIP) from our catalog of antibodies and ELISA kits.

MAB2018
Simple Western lane view shows lysates of BG01V human embryonic stem cells, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 50 kDa (as indicated) using 4 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). This experiment was conducted under reducing conditions and using the <br>12-230 kDa separation system.     Western  blot shows lysates of NTera‑2 human testicular embryonic carcinoma  cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell  line, and rat cortical stem cells. PVDF membrane was probed with  1 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog  # MAB2018) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody  (Catalog # <a class=

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, CyTOF-reported

     12 Reviews

124 Publications
AF1979
Otx2 was detected in immersion fixed NTera‑2 human testicular embryonic carcinoma cell line using Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow, upper panel; Catalog # <A class=NoLineLink href=    Otx2  was detected in immersion fixed paraffin-embedded sections of mouse embryo  (14 d.p.c.) using Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal  Antibody (Catalog # AF1979) at 1 µg/mL for 1 hour at room  temperature followed by incubation with the Anti-Goat IgG VisUCyte™  HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

     6 Reviews

42 Publications
NBP1-84476
Western Blot: CHX10 Antibody [NBP1-84476] - Analysis in control (vector only transfected HEK293T lysate) and vSX2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunohistochemistry-Paraffin: CHX10 Antibody [NBP1-84476] - Staining of human skeletal muscle shows no nuclear positivity in myocytes as expected.

Rabbit Polyclonal
Species Human, Rat
Applications WB, ICC/IF, IHC

5 Publications
H00030062-M02
Immunocytochemistry/Immunofluorescence: RAX Antibody (4F4) [H00030062-M02] - Analysis of monoclonal antibody to RAX on HeLa cell. Antibody concentration 10 ug/ml.Immunohistochemistry-Paraffin: RAX Antibody (4F4) [H00030062-M02] - Analysis of monoclonal antibody to RAX on formalin-fixed paraffin-embedded human adrenal gland. Antibody concentration 3 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
NB300-750
Western Blot: Pax6 Antibody [NB300-750] - Analysis of sheep retinal extractImmunocytochemistry/Immunofluorescence: Pax6 Antibody [NB300-750] - ARPE-19 monolayer on glass substrate. Fixative Methanol Blocking Goat Serum. Dilution 1:100. Incubation 1h @ RT. This image was submitted via customer Review.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

     4 Reviews

4 Publications
314-BP
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=Recombinant Human BMP-4 (Catalog #<BR>314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED<SUB>50</SUB> for this effect is 2.5-15 ng/mL.


Species Human

     8 Reviews

372 Publications
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

H00008575-M01
Western Blot: PACT Antibody (1B9-1A7) [H00008575-M01] - PRKRA monoclonal antibody (M01), clone 1B9-1A7. Analysis of PRKRA expression in human liver.Immunohistochemistry-Paraffin: PACT Antibody (1B9-1A7) [H00008575-M01] - Analysis of monoclonal antibody to PRKRA on formalin-fixed paraffin-embedded human tonsil tissue. Antibody concentration 5 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, IHC

1 Publication
NBP1-82478
Western Blot: SIX6 Antibody [NBP1-82478] - Analysis in control (vector only transfected HEK293T lysate) and SIX6 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).Immunocytochemistry/Immunofluorescence: SIX6 Antibody [NBP1-82478] - Staining of human cell line SH-SY5Y shows localization to nucleoplasm. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

H00064220-D01P
Western Blot: STRA6 Antibody [H00064220-D01P] - Analysis of STRA6 expression in mouse stomach.Western Blot: STRA6 Antibody [H00064220-D01P] - Analysis of STRA6 expression in transfected 293T cell line by STRA6 polyclonal antibody.Lane 1: STRA6 transfected lysate(73.50 KDa).Lane 2: Non-transfected lysate.

Rabbit Polyclonal
Species Human, Mouse, Yeast
Applications WB, IHC, IHC-P

6 Publications
NBP1-91934
Immunocytochemistry/Immunofluorescence: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human cell line LHCN-M2 shows localization to nucleoplasm, nuclear membrane & vesicles. Antibody staining is shown in green.Immunohistochemistry-Paraffin: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human stomach, lower shows strong membranous and cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
464-SH/CF
Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus (Catalog # 464-SH/CF) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The activity is more than 30-fold greater than the top competitor's Sonic Hedgehog.1 μg/lane of Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa.


Species Mouse

40 Publications
H00064093-M03
Western Blot: SMOC-1 Antibody (8F10) [H00064093-M03] - Analysis of SMOC1 expression in A-431 (Cat # L015V1).Immunocytochemistry/Immunofluorescence: SMOC-1 Antibody (8F10) [H00064093-M03] - Analysis of monoclonal antibody to SMOC1 on A-431 cell. Antibody concentration 10 ug/ml

Mouse Monoclonal
Species Human, Zebrafish
Applications WB, ELISA, ICC/IF

NBP1-89090
Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts as well as in Leydig cells.Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human skeletal muscle shows no nuclear positivity in striated muscle fibers as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

NBP1-92273
Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human liver, pancreas, pituitary gland and tonsil using Anti-POU1F1 antibody NBP1-92273 (A) shows similar protein distribution across tissues to independent antibody NBP2-55357 (B).Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human pituitary gland shows moderate to strong nuclear positivity in neuroendocrine cells in the anterior lobe.

Rabbit Polyclonal
Species Human, Mouse
Applications IHC, IHC-P

13 Publications
3 Publications
AF1067
    Western  blot shows lysates of human, mouse, and rat pituitary gland tissue. PVDF  membrane was probed with 0.5 µg/mL of Goat Anti-Human Growth Hormone  Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1067) followed by  HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=    Recombinant  Human Growth Hormone protein was serially diluted 2-fold and captured by  Mouse Anti-Human Growth Hormone Monoclonal Antibody (Catalog # <a class=

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, IHC

     3 Reviews

6 Publications
354-BP


Species Human

     2 Reviews

74 Publications