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Acute Megakaryocytic Leukemias: Disease Bioinformatics

Acute Megakaryocytic Leukemia is a rare form of Acute Myeloid Leukemia most commonly found in adults. The blood cells don’t mature and crowd the normal formation and function of other cells. The disease is so rare that there is not much data collected, making it difficult to recognize the biological characteristics and responses to treatment options. Because of the rarity of Acute Megakaryocytic Leukemia, few patients survive past 3 years.

Acute Megakaryocytic Leukemias Bioinformatics Tool

Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Acute Megakaryocytic Leukemias below! For more information on how to use Laverne, please read the How to Guide.
Vizit™, under license from BioVista Inc.

Top Research Reagents

We have 2398 products for the study of Acute Megakaryocytic Leukemias that can be applied to Western Blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry, Immunohistochemistry from our catalog of antibodies and ELISA kits.

Western Blot: GATA-1 Antibody (4F5) [NBP1-47492] - Western blot analysis using GATA1 mouse mAb against K562 (1) cell lysate.Immunocytochemistry/Immunofluorescence: GATA-1 Antibody (4F5) [NBP1-47492] - Immunofluorescence analysis of K562(left) cells using GATA1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

1 Publication
Western Blot: FANCB Antibody [NBP1-84757] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18<br/>Lane 2: Human cell line RT-4Immunohistochemistry-Paraffin: FANCB Antibody [NBP1-84757] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Western Blot: Mkl1 Antibody [NBP1-88498] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)Immunocytochemistry/Immunofluorescence: Mkl1 Antibody [NBP1-88498] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

5 Publications
Western Blot: Jak2 Antibody [NBP1-22975] - Whole cell lysate from Jurkat and HeLa cells.Immunohistochemistry-Paraffin: Jak2 Antibody [NBP1-22975] - FFPE section of human ovarian carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Immunocytochemistry/Immunofluorescence: CD34 Antibody (MEC 14.7) [NB600-1071] - CD34 antibody was tested in WEHI-3 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).Immunohistochemistry: CD34 Antibody (MEC 14.7) [NB600-1071] - Immunohistochemical analysis of CD34 on mouse renal cancer xenograft.

Rat Monoclonal
Species Mouse
Applications WB, ELISA, Flow

15 Publications

Mouse Monoclonal
Species Human, Rat, Bovine
Applications WB, Func, IA

5 Publications
Western Blot: NOD2 Antibody (2D9) [NB100-524] - Western Blot Image of anti-NOD2 (2D9) Whole cell protein from THP-1 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2 ug/ml anti-NOD2 in 1% milk, and detected with an anti-mouse HRP secondary antibody using chemiluminescence.Immunocytochemistry/Immunofluorescence: NOD2 Antibody (2D9) [NB100-524] - A431 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-NOD2 (2D9) NB100-524 at a 1:200 dilution overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution. Actin was counterstained with Phalloidin 568 (Red) at a 1:200 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.

Mouse Monoclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

12 Publications
Western Blot: HLA DQA1 Antibody [NBP1-84550] - Lane 1: Marker [KDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line Daudi.Immunocytochemistry/Immunofluorescence: HLA DQA1 Antibody [NBP1-84550] - Staining of human cell line U-251MG shows positivity in cytoplasm.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Related Genes

Acute Megakaryocytic Leukemias has been researched against:

Related PTMs

Acute Megakaryocytic Leukemias has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Acute Megakaryocytic Leukemias is also known as Thrombocytic Leukemia, Acute Megakaryoblastic Leukaemia, Acute Megakaryoblastic Leukemia, Acute Megakaryoblastic Leukemia (fab Type M7), Acute Megakaryoblastic Leukemias.