Thrombotic Thrombocytopenic Purpura (TTP) is a rare blood disorder where blood clots form in small vessels throughout the body. Thrombotic Thrombocytopenic Purpura is also associated with an overall decrease in number of platelets in the blood as they become involved in the clots. Bleeding may occur under the skin and appear like small bruises or a rash. Acquired Thrombotic Thrombocytopenic Purpura is different from inherited TTP because the ADAMTs13 gene is not faulty like it is in inherited TTP. Acquired TTP affects mainly adults but may be diagnosed in children. Treatments for this disorder include plasmapheresis which is relatively successful even though many with TTP will experience relapse in their lifetime.
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