WNV Core Products

Antibodies
WNV Core Antibody
WNV Core Antibody
NBP2-41054
Species: Vi
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
WNV Core Antibody
WNV Core Antibody
NBP1-76435
Species: Vi
Applications: ELISA
Host: Rabbit Polyclonal
Proteins
WNV Core Blocking Peptide
WNV Core Blocking Peptide
NBP1-76435PEP
Species: Vi
Applications: AC

Description

West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins (1) which play a major role for WNV entry into target cells (2,3). The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation (4).

Research Areas for WNV Core

Find related products by research area and learn more about each of the different research areas below.

Immunology
Virology, Bacteria and Parasites