UbcH5c/UBE2D3 Products

Description

Position of the Chimera RNAi. The related RNAi products listed were designed from different accesion number but sharing the same RNAi sequence. Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	7323
Alternate Names	E2(17)KB 3 E2(17)KB3 EC 6.3.2.19 MGC43926 MGC5416 UBC4/5 UBC5C UbcH5c UBE2D3 Ubiquitin carrier protein D3 ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2(17)KB 3 Ubiquitin-conjugating enzyme E2-17 kDa 3 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5) ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) Ubiquitin-protein ligase D3

Research Areas for UbcH5c/UBE2D3

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins