Applications: RNAi, RNAi SP
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turncomposed of alpha- and beta-tubulin polymers. Each microtubule is polarized, at one end alpha-subunits are exposed (-)and at the other beta-subunits are exposed (+). Microtubules act as a scaffold to determine cell shape, and provide abackbone for cell organelles and vesicles to move on, a process that requires motor proteins. The major microtubulemotor proteins are kinesin, which generally moves towards the (+) end of the microtubule, and dynein, which generallymoves towards the (-) end. Microtubules also form the spindle fibers for separating chromosomes during mitosis.
|Product By Gene ID
- putative tubulin-like protein alpha-4B
- tubulin, alpha 4b (pseudogene)
Research Areas for TUBA4B
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Bioinformatics Tool for TUBA4B
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