TRIAD3A Products

Antibodies
TRIAD3A Antibody
TRIAD3A Antibody
NB100-56891
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
TRIAD3A Antibody
TRIAD3A Antibody
NBP1-76592
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TRIAD3A Antibody
TRIAD3A Antibody
NB100-66362
Species: Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal

Description

Official Gene Symbol: TRIAD3 Gene ID: 54476 (Human) Gene Map Locus: 7p22.1 (Human) TRIADs are novel zinc finger proteins characterized by the presence of Cysteine rich TRIAD domain consisting of DRIL motif flanked by 2 RING fingers. TRIAD3, a 56KDa protein, is a novel member of this family. It contains 4 RLD domains in the centre and a proline-rich domain at the C-terminus. Localized in the cytoplasm, it interacts with RIP and inhibits TNF and IL1-induced NF-kappaB activation pathways. Reports suggest TRIAD3 acts as an E3-ubiquitin-protein ligase and promotes ubiquitination and degradation of TLR4 and TLR9, thereby regulating TLR signaling. It also interacts with HIV type I Vif protein and interferes in the early events of HIV-1 replication.

Bioinformatics

Entrez Mouse
Uniprot Human
Human
Product By Gene ID 54476
Alternate Names
  • Triad domain-containing protein 3
  • EC 6.3.2.-
  • U7I1
  • UBCE7IP1ubiquitin conjugating enzyme 7 interacting protein 1
  • ZINE3 ubiquitin-protein ligase RNF216
  • TRIAD3Zinc finger protein inhibiting NF-kappa-B
  • ring finger protein 216Ubiquitin-conjugating enzyme 7-interacting protein 1

PTMs for TRIAD3A

Learn more about PTMs related to TRIAD3A.

Ubiquitination
Reduction
Phosphorylation

Bioinformatics Tool for TRIAD3A

Discover related pathways, diseases and genes to TRIAD3A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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