Flow, AgAct, CyTOF-readyHost:
WB, Flow, AgAct, CyTOF-ready, ICCHost:
WB, Flow, AgAct, CyTOF-ready, ELISA(Cap)Host:
Applications: RNAi, RNAi SP
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM]
Research Areas for TREM-1
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for TREM-1
Discover related pathways, diseases and genes to TREM-1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related TREM-1 Blog Posts
Check out the latest blog posts on TREM-1.
Read more TREM-1 related blogs.
|Caspase 11: A novel non-canonical inflammasomes
Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands. This regulated process then transmits downstream signals through adaptor molecules ending with the caspase cysteine proteases. Caspas... Read more.