TPSAB1 Products

Antibodies
TPSAB1 Antibody
TPSAB1 Antibody
NBP2-33551
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
TPSAB1 Recombinant Protein An ...
TPSAB1 Recombinant Protein Antigen
NBP2-33551PEP
Species: Hu
Applications: AC

Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 7177
Alternate Names
  • mast cell alpha II tryptase
  • EC 3.4.21
  • Tryptase-1
  • MGC104064
  • tryptase-III
  • EC 3.4.21.59
  • tryptase-I
  • TPSB1
  • tryptase-1
  • TPS2
  • tryptase beta-1
  • Tryptase I
  • tryptase beta I
  • Tryptase alpha-1
  • tryptase alpha/beta-1
  • tryptase beta 1
  • TPS1tryptase alpha II
  • mast cell beta I tryptase
  • tryptase alpha/beta 1

PTMs for TPSAB1

Learn more about PTMs related to TPSAB1.

Cleavage
Phosphorylation
Glycosylation
Sulphation
Methylation
Myristoylation

Bioinformatics Tool for TPSAB1

Discover related pathways, diseases and genes to TPSAB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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