Host: Armenian Hamster Monoclonal
T cell receptor (TCR) is a heterodimer consisting of an 945; and a 946; chain (TCR 945/946) or a 947; and a 948; chain (TCR 947/948;). TCR 947/948; belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The 947/948; TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most 947/948; T cells are CD4/CD8-, some are CD8+. T cells expressing the 947/948; TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that 947/948; T cells also play a principal role in antigen presentation.
|Product By Gene ID
- T-cell receptor, alpha (V
- T-cell antigen receptor, alpha polypeptide
- T cell receptor alpha locus
Pathways for TCR delta/gamma
View related products by pathway and learn more about each of the pathways below.PathogenesisLocalization
Bioinformatics Tool for TCR delta/gamma
Discover related pathways, diseases and genes to TCR delta/gamma. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.