Synuclein-beta Products

Antibodies
Synuclein-beta Antibody
Synuclein-beta Antibody
NBP1-90342
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Synuclein-beta Antibody
Synuclein-beta Antibody
AF5528
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
Synuclein-beta Antibody (5165 ...
Synuclein-beta Antibody (516505)
MAB5528
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Lysates
Synuclein-beta Overexpression ...
Synuclein-beta Overexpression Lysa...
NBL1-16276
Applications: WB
Synuclein-beta Overexpression ...
Synuclein-beta Overexpression Lysa...
NBL1-16275
Applications: WB
Synuclein-beta Overexpression ...
Synuclein-beta Overexpression Lysa...
H00006620-T01
Applications: WB
Proteins
Synuclein-beta Recombinant Pr ...
Synuclein-beta Recombinant Protein...
NBP1-90342PEP
Species: Hu
Applications: AC
Synuclein-beta Recombinant Pr ...
Synuclein-beta Recombinant Protein
NBC1-18328
Species: Hu
Applications: PAGE

Description

Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies. Alpha-synuclein exists physiologically in both soluble and membrane-bound states, in unstructured and alpha-helical conformations, respectively. The physiological function of alpha-synuclein appears to require its translocation between these subcellular compartments and interconversion between the 2 conformations. Abnormal processing of alpha-synuclein is predicted to lead to pathological changes in its binding properties and function (1).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 6620
Alternate Names
  • beta-synuclein
  • synuclein, beta

Research Areas for Synuclein-beta

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Neuroscience

PTMs for Synuclein-beta

Learn more about PTMs related to Synuclein-beta.

Phosphorylation
Cleavage
Nitration
Biotinylation
Oxidation

Bioinformatics Tool for Synuclein-beta

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