Host: Rabbit Polyclonal
Stella is a gene specifically expressed in primordial germ cells, oocytes, preimplantation embryos, and pluripotent cells. It encodes a protein with a SAP-like domain and a splicing factor motif-like structure, suggesting possible roles in chromosomal organization or RNA processing. We show that while matings between heterozygous animals resulted in the birth of apparently normal stella null offspring, stella-deficient females displayed severely reduced fertility due to a lack of maternally inherited Stella-protein in their oocytes. Embryos without Stella are compromised in preimplantation development and rarely reach the blastocyst stage. Stella is thus one of few known mammalian maternal effect genes.
|Product By Gene ID
- Compaction-associated protein 1
- Stella related protein
- Dppa 3
- Developmental pluripotency-associated 3
- Developmental pluripotency associated protein 3
Bioinformatics Tool for STELLAR
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