SGK Products

Antibodies
SGK Antibody
SGK Antibody
NBP2-19010
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SGK Antibody (4D7-G3)
SGK Antibody (4D7-G3)
H00006446-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
SGK Antibody
SGK Antibody
NBP1-76578
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Proteins
SGK Recombinant Protein
SGK Recombinant Protein
NBP1-99461
Applications: WB, BA
SGK Recombinant Protein
SGK Recombinant Protein
NBP1-72474
Species: Hu
Applications: PAGE
SGK Peptide
SGK Peptide
NBP1-76578PEP
Species: Hu
Applications: AC
RNAi
SGK RNAi
SGK RNAi
H00006446-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
SGK RNAi
SGK RNAi
H00006446-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

SGK1 encodes a serine/threonine protein kinase that is highly similar to the rat serum-and glucocorticoid-induced protein kinase (SGK). This gene was identified in a screen of hepatocellular genes regulated in response to cellular hydration or swelling. Cellular hydration is a catabolic signal, stimulating glycogenolysis and proteolysis, and inhibiting protein and glycogen synthesis. This kinase has been shown to be important in activating certain potassium, sodium, and chloride channels. Expression of this gene in hepatocytes is stimulated by transforming growth factor-beta (TGF-beta) which participates in the pathophysiology of diabetic complications. Since both TGF-beta expression and SGK expression are elevated in diabetic nephropathy, this suggests an involvement of SGK in the development of this condition.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 6446
Alternate Names
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine-protein kinase Sgk1
  • SGK
  • serine/threonine protein kinase SGK
  • Serum/glucocorticoid-regulated kinase 1
  • serum/glucocorticoid regulated kinase
  • serum/glucocorticoid regulated kinase 1

Research Areas for SGK

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair

Bioinformatics Tool for SGK

Discover related pathways, diseases and genes to SGK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.